//Created by libAntimony v2.4 model schlosser_model_2000__environment(time_) // Variable initializations: time_ = ; end model schlosser_model_2000__RP_LH(rel_LH_E2_P4_RP_LH, E2, E2_dE, P4, P4_dP, time_) // Assignment Rules: rel_LH_E2_P4_RP_LH := (kLH_rel * (1.0 + CLH_P * P4) * RP_LH) / (1.0 + CLH_E * E2); syn_LH_E2_P4 := (V0_LH + (V1_LH * power(E2_dE, h)) / (power(Km_LH, h) + power(E2_dE, h))) / (1.0 + P4_dP / Ki_LHP); // Rate Rules: RP_LH' = syn_LH_E2_P4 - rel_LH_E2_P4_RP_LH; // Variable initializations: RP_LH = 467.0; V0_LH = 1400.0; V1_LH = 95900.0; h = 8.0; Km_LH = 360.0; Ki_LHP = 26.0; kLH_rel = 3.0; CLH_P = 0.024; CLH_E = 0.008; E2 = ; E2_dE = ; P4 = ; P4_dP = ; time_ = ; end model schlosser_model_2000__LH(rel_LH_E2_P4_RP_LH, time_) // Assignment Rules: clear_LH := kLH_cl * LH; // Rate Rules: LH' = rel_LH_E2_P4_RP_LH / v_dis - clear_LH; // Variable initializations: LH = 40.0; v_dis = 2.5; kLH_cl = 14.0; rel_LH_E2_P4_RP_LH = ; time_ = ; end model schlosser_model_2000__RP_FSH(rel_FSH_E2_P4_RP_FSH, Ih_dIh, E2, P4, time_) // Assignment Rules: rel_FSH_E2_P4_RP_FSH := (kFSH_rel * (1.0 + CFSH_P * P4) * RP_FSH) / (1.0 + CFSH_E * power(E2, 2.0)); syn_FSH_Ih := V_FSH / (1.0 + Ih_dIh / Ki_FSH_Ih); // Rate Rules: RP_FSH' = syn_FSH_Ih - rel_FSH_E2_P4_RP_FSH; // Variable initializations: RP_FSH = 0.0; V_FSH = 4400.0; Ki_FSH_Ih = 1176.5; kFSH_rel = 45.0; CFSH_P = 3.0; CFSH_E = 0.005; Ih_dIh = ; E2 = ; P4 = ; time_ = ; end model schlosser_model_2000__FSH(rel_FSH_E2_P4_RP_FSH, time_) // Assignment Rules: clear_FSH := kFSH_cl * FSH; // Rate Rules: FSH' = rel_FSH_E2_P4_RP_FSH / v_dis - clear_FSH; // Variable initializations: FSH = 150.0; v_dis = 2.5; kFSH_cl = 8.21; rel_FSH_E2_P4_RP_FSH = ; time_ = ; end model schlosser_model_2000__E2(E2, time_) // Assignment Rules: E2 := (300.0 - (240.0 * power(time_ + 1.0, 2.0)) / (3.0 + power(time_ + 1.0, 2.0))) + 90.0 * exp(-(power(time_ - 8.0, 2.0) / 10.0)); // Variable initializations: time_ = ; end model schlosser_model_2000__E2_dE(E2_dE, time_) // Assignment Rules: E2_dE := (300.0 - (240.0 * power((time_ + 1.0) - dE, 2.0)) / (3.0 + power((time_ + 1.0) - dE, 2.0))) + 90.0 * exp(-(power(time_ - (dE + 8.0), 2.0) / 10.0)); // Variable initializations: dE = 0.42; time_ = ; end model schlosser_model_2000__P4(P4, time_) // Assignment Rules: P4 := 52.0 * exp(-(power(time_ - 7.0, 2.0) / 18.0)); // Variable initializations: time_ = ; end model schlosser_model_2000__P4_dP(P4_dP, time_) // Assignment Rules: P4_dP := 52.0 * exp(-(power(time_ - (dP + 7.0), 2.0) / 18.0)); // Variable initializations: dP = 2.9; time_ = ; end model schlosser_model_2000__Ih(Ih, time_) // Assignment Rules: Ih := 300.0 + 1330.0 * exp(-(power(time_ - 7.0, 2.0) / 19.0)); // Variable initializations: time_ = ; end model schlosser_model_2000__Ih_dIh(Ih_dIh, time_) // Assignment Rules: Ih_dIh := 300.0 + 1330.0 * exp(-(power(time_ - (7.0 + dIh), 2.0) / 19.0)); // Variable initializations: dIh = 2.0; time_ = ; end model *schlosser_model_2000____main() // Sub-modules, and any changes to those submodules: environment: schlosser_model_2000__environment(time_); RP_LH: schlosser_model_2000__RP_LH(rel_LH_E2_P4_RP_LH, E20, E2_dE0, P40, P4_dP0, time_); LH: schlosser_model_2000__LH(rel_LH_E2_P4_RP_LH, time_); RP_FSH: schlosser_model_2000__RP_FSH(rel_FSH_E2_P4_RP_FSH, Ih_dIh0, E20, P40, time_); FSH: schlosser_model_2000__FSH(rel_FSH_E2_P4_RP_FSH, time_); E2: schlosser_model_2000__E2(E20, time_); E2_dE: schlosser_model_2000__E2_dE(E2_dE0, time_); P4: schlosser_model_2000__P4(P40, time_); P4_dP: schlosser_model_2000__P4_dP(P4_dP0, time_); Ih: schlosser_model_2000__Ih(Ih0, time_); Ih_dIh: schlosser_model_2000__Ih_dIh(Ih_dIh0, time_); end