k_on R_off f_prime A_1 g A_2 k_off f D f D h_prime A_2 f_prime h A_1 h A_1 h_prime g A_2 R_T D A_1 A_2 dSL_dt A_1 0 f D A_1 h_prime A_2 A_1 x_1 dSL_dt dSL_dt A_2 0 h A_1 A_2 x_2 x_0 dSL_dt g_0 sigma x_2 x_0 2 f_r 1 lambda_A1 x_1 x_0 nu 1 1 lambda_A2 x_2 x_0 nu 1 1 2 h_0 sigma x_1 2 A_1 R_T A_2 R_T E_1 x_1 E_2 x_2 e_cb A_1 e_cb A_2 21.2 time_ 0.001 time_ 0.002 0 dSL_dt f_prime_0 sigma x_1 2 h_prime_0 sigma x_2 2 x_1 2 sigma_plus x_2 x_0 sigma_minus x_2 x_0 0