$\mathrm{D\_OB\_u}\mathrm{pi\_TGF\_beta\_act}-\mathrm{D\_OB\_p}\mathrm{pi\_TGF\_beta\_rep}\mathrm{OB\_p}+\mathrm{pd\_OB\_p}$ $\mathrm{D\_OB\_p}\mathrm{pi\_TGF\_beta\_rep}\mathrm{OB\_p}-\mathrm{A\_OB\_a}\mathrm{OB\_a}+\mathrm{pd\_OB\_a}$ $\mathrm{D\_OC\_p}\mathrm{pi\_RANKL\_act}-\mathrm{A\_OC\_a}\mathrm{pi\_TGF\_beta\_act}\mathrm{OC\_a}+\mathrm{pd\_OC\_a}$ $\begin{cases}2.1E-2 & \text{if $(\mathrm{time\_}> 0)\land (\mathrm{time\_}\le 100)$}\\ 2.1E-3 & \text{otherwise}\end{cases}$ $\mathrm{k\_form}(\mathrm{OB\_a}-\mathrm{OB\_a\_initial})-\mathrm{k\_res}(\mathrm{OC\_a}-\mathrm{OC\_a\_initial})$ $\frac{\mathrm{alpha}\mathrm{OC\_a}}{\mathrm{KD\_TGF\_activate}+\mathrm{alpha}\mathrm{OC\_a}}$ $\frac{1}{1+\frac{\mathrm{alpha}\mathrm{OC\_a}}{\mathrm{KD\_TGF\_repress}}}$ $\frac{\mathrm{PTH\_tot}}{\mathrm{PTH\_tot}+\mathrm{KD\_PTH\_activate}}$ $\frac{1}{1+\frac{\mathrm{PTH\_tot}}{\mathrm{KD\_PTH\_repress}}}$ $\frac{\mathrm{beta\_PTH}+\mathrm{P\_PTH\_d}}{\mathrm{Deg\_PTH}}$ $\frac{\mathrm{P\_OPG\_d}+\mathrm{OPG\_eff}}{\frac{\mathrm{OPG\_eff}}{\mathrm{OPG\_max}}+\mathrm{Deg\_OPG}}$ $(\mathrm{beta1\_OB\_p\_OPG}\mathrm{beta\_OPG}\mathrm{OB\_p}+\mathrm{beta2\_OB\_a\_OPG}\mathrm{beta\_OPG}\mathrm{OB\_a})\mathrm{pi\_PTH\_rep}$ $\mathrm{Deg\_OPG}\mathrm{OPG}$ $\mathrm{OPG\_eff}(1-\frac{\mathrm{OPG}}{\mathrm{OPG\_max}})+\mathrm{P\_OPG\_d}$ $\frac{\mathrm{RANKL\_RANK}}{\mathrm{KD\_RANKL\_activate}+\mathrm{RANKL\_RANK}}$ $\frac{\mathrm{beta\_RANKL}+\mathrm{P\_RANKL\_d}}{\mathrm{RANKL\_tot}(\frac{\mathrm{beta\_RANKL}}{\mathrm{RANKL\_eff}}+\mathrm{Deg\_RANKL})}$ $(\mathrm{K\_RANKL\_OB\_p}\mathrm{OB\_p}+\mathrm{K\_RANKL\_OB\_a}\mathrm{OB\_a})\mathrm{pi\_PTH\_act}$ $1+\mathrm{K\_A2\_RANKL}\mathrm{RANK}+\mathrm{K\_A1\_RANKL}\mathrm{OPG}$ $\mathrm{R1\_OB\_p\_RANKL}\mathrm{R\_RANKL}$ $\mathrm{R2\_OB\_a\_RANKL}\mathrm{R\_RANKL}$ $\mathrm{K\_A1\_RANKL}\mathrm{OPG}\mathrm{RANKL}$ $\mathrm{K\_A2\_RANKL}\mathrm{RANKL}\mathrm{RANK}$ $\mathrm{beta\_RANKL}(1-\mathrm{RANKL}\frac{\mathrm{RANKL\_tot}}{\mathrm{RANKL\_eff}})-\mathrm{Deg\_RANKL}\mathrm{RANKL}\mathrm{RANKL\_tot}+\mathrm{P\_RANKL\_d}$