0.001 i_NaT i_NaP i_leakNa i_KDR i_KA i_leakK i_leakf i_NaKATPase_n i_app Cm 4500 time_ t0 time_ t1 0 alpha_m 1 m beta_m m 0.32 Vm_n 51.9 0.25 Vm_n 12.975 1 0.28 Vm_n 24.89 0.2 Vm_n 4.978 1 alpha_h 1 h beta_h h 0.128 0.056 Vm_n 2.94 4 0.2 Vm_n 6 1 gNaT m 3 h Vm_n ENa_n gNaT m 3 h Vm_n ENa_n F alpha_m 1 m beta_m m 1 tau_activation 1 0.143 Vm_n 5.67 1 1 tau_activation 0.143 Vm_n 5.67 0.143 Vm_n 5.67 1 alpha_h 1 h beta_h h 5.12 -8 0.056 Vm_n 2.94 1.6 -6 0.2 Vm_n 8 1 gNaP m 2 h Vm_n ENa_n gNaP m 2 h Vm_n ENa_n F alpha_n 1 n beta_n n 0.016 Vm_n 34.9 0.2 Vm_n 6.98 1 0.25 0.025 Vm_n 1.25 gKDR n 2 Vm_n EK_n gKDR n 2 Vm_n EK_n F alpha_m 1 m beta_m m 0.02 Vm_n 56.9 0.1 Vm_n 5.69 1 0.0175 Vm_n 29.9 0.1 Vm_n 2.99 1 alpha_h 1 h beta_h h 0.016 0.056 Vm_n 4.61 0.5 0.2 Vm_n 11.98 1 gKA m 2 h Vm_n EK_n gKA m 2 h Vm_n EK_n F J_NaKATPase_n F I_NaKATPase_n_max Nan_ 1.5 Nan_ 1.5 KmNa 1.5 Ko Ko KmK gleakNa Vm_n ENa_n gleakNa Vm_n ENa_n F gleakK Vm_n EK_n gleakK Vm_n EK_n F gleakf Vm_n Ef_n gNa ENa_g gK EK_g gCl ECl_g gNBC ENBC_g gNa gK gCl gNBC F J_NaKATPase_g gNa gK gCl gNBC gNa Vm_g ENa_g F gK Vm_g EK_g F I_NaKATPase_g_max Nag 1.5 Nag 1.5 KmNa 1.5 Ko Ko KmK gNBC Vm_g ENBC_g F Ko P_Ko 10 Ko P_Ko 10 0.03 10 Psi gNKCC1 Ko Kg Nao Nag Clo Clg 2 F Ko P_Ko 0 dN_Nag_dt 0.01 J_Na 3 J_NaKATPase_g J_NKCC1 J_NBC dN_Kg_dt 0.01 J_K 2 J_NaKATPase_g J_NKCC1 10 Lp Nag Kg Clg HCO3g Xg wg Nao Ko Clo HCO3o P_wg P_wo wg 0.01 3 J_NaKATPase_n J_NaT J_NaP J_leakNa 100 dN_Nag_dt -0.01 J_NaT J_NaP J_leakNa 3 J_NaKATPase_n dN_Kg_dt -0.01 2 J_NBC Psi Nao Nan_ Psi Ko Kn Psi Nao Nag Psi Ko Kg -1 Psi Clo Clg Psi Nao Nag HCO3o HCO3g 2 P_wg P_Clg P_wo P_Clo P_wn P_Cln wg Clg P_wn Cln wo P_Cln Nan_ P_Nan Kn P_Kn Nag Kg HCO3g rho Xg wg P_wn P_Nan P_wg P_Nag P_wo P_Nao N_Nao N_Nag P_wn N_Nao wo N_Nag wg P_wn P_Kn P_wg P_Kg P_wo P_Ko N_Ko N_Kg P_wn N_Ko wo N_Kg wg P_wg P_HCO3g P_wo P_HCO3o N_HCO3o wg N_HCO3o wo P_Nao P_Ko P_HCO3o P_Clo P_Vm_g Psi P_HCO3o P_Nao P_Nag P_Vm_g Psi 1000 R T F