//Created by libAntimony v2.4
model fallon_lauffenburger_2000__environment(time_)

  // Variable initializations:
  time_ = ;
end

model fallon_lauffenburger_2000__Rs(Rs, L, Cs, Vs, kf, kr, kt, ksyn, time_)

  // Rate Rules:
  Rs' = ((kr + ksyn) * Cs + Vs) - (kf * L * Rs + kt * Rs);

  // Variable initializations:
  Rs = 1500;
  L = ;
  Cs = ;
  Vs = ;
  kf = ;
  kr = ;
  kt = ;
  ksyn = ;
  time_ = ;
end

model fallon_lauffenburger_2000__Cs(Cs, L, Rs, kf, kr, ke, time_)

  // Rate Rules:
  Cs' = kf * L * Rs - (kr + ke) * Cs;

  // Variable initializations:
  Cs = 1;
  L = ;
  Rs = ;
  kf = ;
  kr = ;
  ke = ;
  time_ = ;
end

model fallon_lauffenburger_2000__Ri(Ri, Li, Ci, Rs, kfe, kre, kt, kh, time_)

  // Rate Rules:
  Ri' = (kre * Ci + kt * Rs) - (kfe * Li * Ri + kh * Ri);

  // Variable initializations:
  Ri = 300;
  Li = ;
  Ci = ;
  Rs = ;
  kfe = ;
  kre = ;
  kt = ;
  kh = ;
  time_ = ;
end

model fallon_lauffenburger_2000__Ci(Ci, Li, Ri, Cs, kfe, kre, ke, kh, time_)

  // Rate Rules:
  Ci' = (kfe * Li * Ri + ke * Cs) - (kre + kh) * Ci;

  // Variable initializations:
  Ci = 1;
  Li = ;
  Ri = ;
  Cs = ;
  kfe = ;
  kre = ;
  ke = ;
  kh = ;
  time_ = ;
end

model fallon_lauffenburger_2000__Li(Li, Ci, Ri, kfe, kre, kx, Ve, NA, time_)

  // Rate Rules:
  Li' = (kre * Ci - kfe * Li * Ri) / (Ve * NA) - kx * Li;

  // Variable initializations:
  Li = 0.01;
  Ci = ;
  Ri = ;
  kfe = ;
  kre = ;
  kx = ;
  Ve = ;
  NA = ;
  time_ = ;
end

model fallon_lauffenburger_2000__Ld(Ld, Ci, kh, time_)

  // Rate Rules:
  Ld' = kh * Ci;

  // Variable initializations:
  Ld = 1;
  Ci = ;
  kh = ;
  time_ = ;
end

model fallon_lauffenburger_2000__L(L, Rs, Cs, Li, Y, kf, kr, kx, Ve, NA, time_)

  // Rate Rules:
  L' = (((kr * Cs + kx * Li * Ve * NA) - kf * L * Rs) * Y) / NA;

  // Variable initializations:
  L = 10;
  Rs = ;
  Cs = ;
  Li = ;
  Y = ;
  kf = ;
  kr = ;
  kx = ;
  Ve = ;
  NA = ;
  time_ = ;
end

model fallon_lauffenburger_2000__Y(Y, Cs, time_)

  // Rate Rules:
  Y' = piecewise( ((600 * Cs) / (250 + Cs) - 200) * 1E3 , (600 * Cs) / (250 + Cs) - 200 > 0 , 0 );

  // Variable initializations:
  Y = 2.5e8;
  Cs = ;
  time_ = ;
end

model fallon_lauffenburger_2000__model_parameters(kr, kf, kre, kfe, kt, Vs, ksyn, ke, kx, kh, Ve, NA)

  // Assignment Rules:
  kf := piecewise( kr / 11.1 , IL2 == 1 , kr / 8.2 );
  kre := piecewise( kr * 8 , IL2 == 1 , kr * 5 );
  kfe := piecewise( kre / 1000 , IL2 == 1 , kre / 3000 );

  // Variable initializations:
  kr = 0.0138;
  kt = 0.007;
  Vs = 11;
  ksyn = 0.0011;
  ke = 0.04;
  kx = 0.15;
  kh = 0.035;
  Ve = 1e-14;
  NA = 6.022e11;
  IL2 = 1;
end

model *fallon_lauffenburger_2000____main()

  // Sub-modules, and any changes to those submodules:
  environment: fallon_lauffenburger_2000__environment(time_);
  Rs: fallon_lauffenburger_2000__Rs(Rs0, L0, Cs0, Vs, kf, kr, kt, ksyn, time_);
  Cs: fallon_lauffenburger_2000__Cs(Cs0, L0, Rs0, kf, kr, ke, time_);
  Ri: fallon_lauffenburger_2000__Ri(Ri0, Li0, Ci0, Rs0, kfe, kre, kt, kh, time_);
  Ci: fallon_lauffenburger_2000__Ci(Ci0, Li0, Ri0, Cs0, kfe, kre, ke, kh, time_);
  Li: fallon_lauffenburger_2000__Li(Li0, Ci0, Ri0, kfe, kre, kx, Ve, NA, time_);
  Ld: fallon_lauffenburger_2000__Ld(Ld0, Ci0, kh, time_);
  L: fallon_lauffenburger_2000__L(L0, Rs0, Cs0, Li0, Y0, kf, kr, kx, Ve, NA, time_);
  Y: fallon_lauffenburger_2000__Y(Y0, Cs0, time_);
  model_parameters: fallon_lauffenburger_2000__model_parameters(kr, kf, kre, kfe, kt, Vs, ksyn, ke, kx, kh, Ve, NA);
end