//Created by libAntimony v2.4
model dupont_1992b_1_1model__environment(time_)

  // Variable initializations:
  time_ = ;
end

model dupont_1992b_1_1model__parameters(kf, k, Y, Z, v2, v3)

  // Assignment Rules:
  v2 := (VM2 * power(Z, n)) / (power(KP, n) + power(Z, n));
  v3 := VM3 * (power(Y, m) / (power(KR, m) + power(Y, m))) * (power(Z, p) / (power(KA, p) + power(Z, p)));

  // Variable initializations:
  VM2 = 65;
  VM3 = 500;
  KR = 2;
  KA = 0.9;
  KP = 1;
  n = 2;
  m = 2;
  p = 4;
  kf = 1;
  k = 10;
  Y = ;
  Z = ;
end

model dupont_1992b_1_1model__cytosol(time_, v2, v3, kf, k, Y, Z)

  // Rate Rules:
  Z' = (((v0 + v1beta) - v2) + v3 + kf * Y) - k * Z;

  // Variable initializations:
  time_ = ;
  v0 = 1;
  v1beta = 2.4;
  v2 = ;
  v3 = ;
  kf = ;
  k = ;
  Y = ;
  Z = 0.2281;
end

model dupont_1992b_1_1model__insensitive_pool(time_, v2, v3, kf, Y)

  // Rate Rules:
  Y' = (v2 - v3) - kf * Y;

  // Variable initializations:
  time_ = ;
  v2 = ;
  v3 = ;
  kf = ;
  Y = 1.454;
end

model dupont_1992b_1_1model__kinase_reaction(vMK, Z, vK)

  // Assignment Rules:
  vK := vMK * (power(Z, q) / (power(Ka, q) + power(Z, q)));

  // Variable initializations:
  vMK = 100;
  Ka = 1;
  q = 4;
  Z = ;
end

model dupont_1992b_1_1model__phosphorylation(time_, vK, Z, vMK)

  // Sub-modules, and any changes to those submodules:
  kinase_reaction: dupont_1992b_1_1model__kinase_reaction(vMK, Z, vK);

  // Assignment Rules:
  vP := vMK * (0.89 / 20);

  // Rate Rules:
  Wstar' = (vP / WT) * (((vK / vP) * (1 - Wstar)) / ((K1 + 1) - Wstar) - Wstar / (K2 + Wstar));

  // Variable initializations:
  time_ = ;
  K1 = 0.01;
  K2 = 0.01;
  WT = 10;
  Wstar = 0.8916;
end

model *dupont_1992b_1_1model____main()

  // Sub-modules, and any changes to those submodules:
  environment: dupont_1992b_1_1model__environment(time_);
  parameters: dupont_1992b_1_1model__parameters(kf, k, Y, Z, v2, v3);
  cytosol: dupont_1992b_1_1model__cytosol(time_, v2, v3, kf, k, Y, Z);
  insensitive_pool: dupont_1992b_1_1model__insensitive_pool(time_, v2, v3, kf, Y);
  phosphorylation: dupont_1992b_1_1model__phosphorylation(time_, vK, Z, vMK);
end