-1 Cm i_Na i_Ca_L i_Ca_T i_Kr i_Ks i_K_Na i_K_ATP i_to i_K1 i_Kp i_NaCa i_p_Ca i_Na_b i_Ca_b i_NaK i_ns_Ca I_st stim_amplitude time_ stim_start time_ stim_end time_ stim_start time_ stim_start stim_period stim_period stim_duration 0 -1 Cm i_Na i_Ca_L i_Ca_T i_Kr i_Ks i_K_Na i_K_ATP i_to i_K1 i_Kp i_NaCa i_p_Ca i_Na_b i_Ca_b i_NaK i_ns_Ca I_st alpha_2 beta_13 P_O_Na beta_2 P_IF alpha_13 P_C1 beta_12 alpha_13 beta_3 P_C1 alpha_12 P_C2 beta_13 P_O_Na alpha_3 P_IF beta_11 alpha_12 P_C2 alpha_11 P_C3 beta_12 P_C1 beta_11 P_C2 alpha_11 P_C3 beta_2 alpha_3 alpha_4 P_IF beta_3 P_C1 beta_4 P_IS alpha_2 P_O_Na alpha_4 P_IF beta_4 P_IS 3802 0.1027 V 17 0.2 V 150 191.7 V 20.3 3802 0.1027 V 15 0.23 V 150 200 V 5 20.3 3802 0.1027 V 12 0.25 V 150 220 V 10 20.3 9178 V 29.68 alpha_13 alpha_2 alpha_3 beta_13 beta_3 3.7933 -7 V 5.2 8.4 0.02 V alpha_2 100 alpha_3 g_Na P_O_Na V E_Na R T F Nao Nai alpha_d 1 d beta_d d d_infinity tau_d 1 d_infinity tau_d 1 1 E0_d 6.24 0.001 0.035 6.24 E0_d 1 -5 0.001 d_infinity 1 E0_d 6.24 0.035 E0_d V 10 alpha_f 1 f beta_f f f_infinity tau_f 1 f_infinity tau_f 1 1 V 32 8 0.6 1 50 V 20 0.001 0.0197 0.0337 V 10 2 0.02 1 1 Cai Km_Ca i_CaCa i_CaK i_CaNa d f f_Ca I_CaCa d f f_Ca I_CaK d f f_Ca I_CaNa P_Ca 2 2 V F 2 R T gamma_Cai Cai 2 V F R T gamma_Cao Cao 2 V F R T 1 P_K 1 2 V F 2 R T gamma_Ki Ki 1 V F R T gamma_Ko Ko 1 V F R T 1 P_Na 1 2 V F 2 R T gamma_Nai Nai 1 V F R T gamma_Nao Nao 1 V F R T 1 b_inf b tau_b 1 1 V 14 10.8 0.0037 0.0061 1 V 25 4.5 g_inf g tau_g 1 1 V 60 5.6 -0.000875 V 0.012 V 0 0.012 g_CaT b b g V E_Ca beta_beta beta_i P_O alpha_alpha P_C1 alpha_i P_I beta_in alpha_alpha alpha_alpha P_C1 alpha_in P_C2 beta_beta P_O mu P_I beta alpha_in P_C2 alpha P_C3 beta_in P_C1 beta P_C2 alpha P_C3 mu alpha_i P_I alpha_alpha P_C1 beta_i P_O 55.5 0.05547153 V 12 2.357 -0.036588 V 65.5 0.05547153 V 36 2.9357 -0.02158 V 439 -0.02352 V 25 4.5 Ko 656 0.000942 V 4.5 Ko 0.3 alpha_i beta_beta alpha_alpha alpha_alpha beta_i i_Kr_factor g_Kr P_O V E_Kr 2.7 0.0135 Ko 0.59 R T F Ko Ki xs1_infinity xs1 tau_xs1 1 1 V 1.5 16.7 0.001 7.19 -5 V 30 1 -0.148 V 30 0.000131 V 30 0.0687 V 30 1 xs2_infinity xs2 tau_xs2 1 1 V 1.5 16.7 4 0.001 7.19 -5 V 30 1 -0.148 V 30 0.000131 V 30 0.0687 V 30 1 g_Ks xs1 xs2 V E_Ks 0.433 1 0.6 1 3.8 -5 Cai 1.4 R T F Ko PNaK Nao Ki PNaK Nai alpha_K1 alpha_K1 beta_K1 1020 1 0.2385 V E_K 59.215 1000 0.49124 0.08032 V E_K 5.476 0.06175 V E_K 594.31 1 -0.5143 V E_K 4.753 g_K1 K1_infinity V E_K R T F Ko Ki 0.75 Ko 5.4 g_Kp Kp V E_K 1 1 7.488 V 5.98 g_K_Na pona pov V E_K 0 0.12848 0.85 1 kdKNa Nai nKNa 0.8 0.65 1 V 125 15 GKbaraATP V E_K i_K_ATP_on 0.000193 nicholsarea 1 1 ATPi kATP hATP g_K_ATP pATP Ko 4 nATP zdv_ss zdv tau_zdv 10000 V 40 25 1 V 40 25 10000 V 90 25 1 V 90 25 1 alpha_zdv beta_zdv alpha_zdv alpha_zdv beta_zdv ydv_ss ydv tau_ydv 15 1 V 60 5 100 V 25 5 1 V 25 5 1 alpha_ydv beta_ydv alpha_ydv alpha_ydv beta_ydv g_to zdv 3 ydv rvdv V E_K 0 0.5 V 100 I_pCa Cai K_mpCa Cai g_Nab V E_Na g_Cab V E_Ca R T 2 F Cao Cai I_NaK f_NaK 1 1 K_mNai Nai 2 Ko Ko K_mKo 1 1 0.1245 -0.1 V F R T 0.0365 sigma V F R T 1 7 Nao 67.3 1 i_ns_Na i_ns_K I_ns_Na 1 1 K_m_ns_Ca Cai 3 I_ns_K 1 1 K_m_ns_Ca Cai 3 0 1.75 -7 P_ns_Ca 1 2 V F 2 R T gamma_Nai Nai 1 V F R T gamma_Nao Nao 1 V F R T 1 P_ns_Ca 1 2 V F 2 R T gamma_Ki Ki 1 V F R T gamma_Ko Ko 1 V F R T 1 c1 gamma 1 V F R T V F R T Nai 3 Cao Nao 3 Cai 1 c2 gamma 1 V F R T V F R T Nai 3 Cao Nao 3 Cai G_rel Ca_JSR Cai I_up Cai Cai K_mup K_leak Ca_NSR Ca_NSR Ca_JSR tau_tr G_rel_max Cainfluxtrack delta_Ca_ith K_mrel Cainfluxtrack delta_Ca_ith 1 APtrack2 APtrack2 Cainfluxtrack delta_Ca_ith G_rel_overload 1 OVRLDtrack2 OVRLDtrack2 Cainfluxtrack delta_Ca_ith OVRLDtrack2 0 0 I_up Ca_NSR_max 1 1 CMDN_max K_mCMDN K_mCMDN Cai 2 Tn_max K_mTn K_mTn Cai 2 A_cap i_CaCa i_Ca_T 2 i_NaCa i_p_Ca i_Ca_b 2 V_myo F i_rel V_JSR V_myo i_leak i_up V_NSR V_myo 1 1 CSQN_max K_mCSQN K_mCSQN Ca_JSR 2 i_tr i_rel i_tr V_JSR V_NSR i_leak i_up 0.0048 0.68 V_myo 0.0552 0.68 V_myo 100000 1 APtrack 500 APtrack dVdt 150000 -500 APtrack 100000 1 APtrack2 500 APtrack2 APtrack 0.2 APtrack 0.18 -500 APtrack2 100000 1 APtrack3 500 APtrack3 APtrack 0.2 APtrack 0.18 -10 APtrack3 A_cap i_CaCa i_Ca_T i_NaCa i_p_Ca i_Ca_b 2 V_myo F APtrack 0.2 0 APtrack2 0.01 APtrack 0.2 -500 Cainfluxtrack 50000 1 OVRLDtrack 1 1 K_mCSQN Ca_NSR CSQNthresh OVRLDtrack3 0.37 APtrack3 0.37 -500 OVRLDtrack 50000 1 OVRLDtrack2 OVRLDtrack Logicthresh OVRLDtrack2 Logicthresh -500 OVRLDtrack2 50000 1 OVRLDtrack3 OVRLDtrack Logicthresh OVRLDtrack3 Logicthresh -10 OVRLDtrack3 0 i_Na i_CaNa i_Na_b i_ns_Na i_NaCa 3 i_NaK 3 A_cap V_myo F 0 i_CaK i_Kr i_Ks i_K1 i_Kp i_K_Na i_K_ATP i_to i_ns_K i_NaK 2 A_cap V_myo F 0.68 volume