//Created by libAntimony v2.4
model bi_model_1999_version01__environment(t)

  // Variable initializations:
  t = ;
end

model bi_model_1999_version01__PIPtoDAG(t, CaPLCg, CaPLCg_star)

  // Rate Rules:
  PIP2' = (- CaPLCg * Vmax2 * PIP2) / (km2 + PIP2) - (CaPLCg_star * Vmax6 * PIP2) / (km6 + PIP2);
  DAG' = (CaPLCg * Vmax2 * PIP2) / (km2 + PIP2) + (CaPLCg_star * Vmax6 * PIP2) / (km6 + PIP2);
  IP3' = (CaPLCg * Vmax2 * PIP2) / (km2 + PIP2) + (CaPLCg_star * Vmax6 * PIP2) / (km6 + PIP2);

  // Variable initializations:
  t = ;
  km2 = 97;
  km6 = 19.79166667;
  Vmax2 = 14;
  Vmax6 = 57;
  PIP2 = 10;
  DAG = 0;
  IP3 = 0;
  CaPLCg = ;
  CaPLCg_star = ;
end

model bi_model_1999_version01__PLC(t, CaPLCg, CaPLCg_star, EGF_EGFR)

  // Rate Rules:
  PLCg' = - Ca * PLCg * kf1 + CaPLCg * kb1;
  PLCg_star' = - Ca * PLCg_star * kf5 + kb5 * CaPLCg_star;
  CaPLCg' = (-(- Ca * PLCg * kf1 + CaPLCg * kb1) + kf3 * CaPLCg_star) - (Vmax4 * EGF_EGFR * CaPLCg) / (km4 + CaPLCg);
  CaPLCg_star' = (-(kf3 * CaPLCg_star - (Vmax4 * EGF_EGFR * CaPLCg) / (km4 + CaPLCg)) + Ca * PLCg_star * kf5) - kb5 * CaPLCg_star;
  Ca' = (- Ca * PLCg * kf1 + CaPLCg * kb1 + kb5 * CaPLCg_star) - Ca * PLCg_star * kf5;

  // Variable initializations:
  t = ;
  kf1 = 0.0003;
  kb1 = 10;
  kf3 = 0.05;
  kf5 = 0.00002;
  kb5 = 10;
  km4 = 0.33333333333;
  Vmax4 = 0.2;
  PLCg = 0.82;
  PLCg_star = 0;
  CaPLCg = 0;
  CaPLCg_star = 0;
  EGF_EGFR = ;
  Ca = 0.1;
end

model bi_model_1999_version01__UndefinedVariables(EGF_EGFR)

  // Variable initializations:
  EGF_EGFR = 0.1;
end

model *bi_model_1999_version01____main()

  // Sub-modules, and any changes to those submodules:
  environment: bi_model_1999_version01__environment(t);
  PIPtoDAG: bi_model_1999_version01__PIPtoDAG(t, CaPLCg, CaPLCg_star);
  PLC: bi_model_1999_version01__PLC(t, CaPLCg, CaPLCg_star, EGF_EGFR);
  UndefinedVariables: bi_model_1999_version01__UndefinedVariables(EGF_EGFR);
end