//Created by libAntimony v2.4
model bi_model_1999_version01__environment(t)

  // Variable initializations:
  t = ;
end

model bi_model_1999_version01__PLA2(t, CaPLA2, PIP2CaPLA2, PIP2PLA2, DAGCaPLA2, CaPLA2_star)

  // Rate Rules:
  PIP2_star' = - PIP2_star * CaPLA2 * kf5 + PIP2CaPLA2 * kb5;
  PLA2_cyt' = ((((PLA2_star * kf10 - PIP2_star * PLA2_cyt * kf1) + PIP2PLA2 * kb1) - Ca * PLA2_cyt * kf3) + CaPLA2 * kb3) - (MAPK * Vmax9 * PLA2_cyt) / (km9 + PLA2_cyt);
  PLA2_star' = ((- PLA2_star * kf10 + (MAPK * Vmax9 * PLA2_cyt) / (km9 + PLA2_cyt)) - Ca * PLA2_star * kf11) + CaPLA2_star * kb11;
  Ca' = ((- Ca * PLA2_star * kf11 + CaPLA2_star * kb11) - Ca * PLA2_cyt * kf3) + CaPLA2 * kb3;
  CaPLA2' = ((((Ca * PLA2_cyt * kf3 - CaPLA2 * kb3) - DAG * CaPLA2 * kf7) + DAGCaPLA2 * kb7) - PIP2_star * CaPLA2 * kf5) + PIP2CaPLA2 * kb5;
  DAG' = - DAG * CaPLA2 * kf7 + DAGCaPLA2 * kb7;
  PIP2CaPLA2' = PIP2_star * CaPLA2 * kf5 - PIP2CaPLA2 * kb5;
  PIP2PLA2' = PIP2_star * PLA2_cyt * kf1 - PIP2PLA2 * kb1;
  DAGCaPLA2' = DAG * CaPLA2 * kf7 - DAGCaPLA2 * kb7;
  CaPLA2_star' = Ca * PLA2_star * kf11 - CaPLA2_star * kb11;

  // Variable initializations:
  t = ;
  kf1 = 0.000000002;
  kb1 = 0.5;
  kf3 = 0.00000016667;
  kb3 = 0.1;
  kf5 = 0.00000002;
  kb5 = 0.1;
  kf7 = 0.000000005;
  kb7 = 4;
  kf10 = 0.17;
  kb10 = 0;
  kf11 = 0.00001;
  kb11 = 0.1;
  km9 = 25.64166667;
  Vmax9 = 20;
  PIP2_star = 2.5;
  PLA2_cyt = 0.4;
  MAPK = 0.1;
  PLA2_star = 0;
  Ca = 0.1;
  CaPLA2 = 0;
  DAG = 0.01;
  PIP2CaPLA2 = 0;
  PIP2PLA2 = 0;
  DAGCaPLA2 = 0;
  CaPLA2_star = 0;
end

model bi_model_1999_version01__AA(t, CaPLA2, DAGCaPLA2, CaPLA2_star, PIP2PLA2, PIP2CaPLA2)

  // Rate Rules:
  AA' = - AA * kf13 + (CaPLA2_star * Vmax12 * APC) / (km12 + APC) + (CaPLA2 * Vmax4 * APC) / (km4 + APC) + (DAGCaPLA2 * Vmax8 * APC) / (km8 + APC) + (PIP2CaPLA2 * Vmax6 * APC) / (km6 + APC) + (PIP2PLA2 * Vmax2 * APC) / (km2 + APC);
  APC' = AA * kf13 - ((CaPLA2_star * Vmax12 * APC) / (km12 + APC) + (CaPLA2 * Vmax4 * APC) / (km4 + APC) + (DAGCaPLA2 * Vmax8 * APC) / (km8 + APC) + (PIP2CaPLA2 * Vmax6 * APC) / (km6 + APC) + (PIP2PLA2 * Vmax2 * APC) / (km2 + APC));

  // Variable initializations:
  t = ;
  kf13 = 0.4;
  kb13 = 0;
  km2 = 20;
  km4 = 20;
  km6 = 20;
  km8 = 20;
  km12 = 20;
  Vmax2 = 11.04;
  Vmax4 = 5.4;
  Vmax6 = 36;
  Vmax8 = 60;
  Vmax12 = 120;
  CaPLA2 = ;
  DAGCaPLA2 = ;
  CaPLA2_star = ;
  PIP2PLA2 = ;
  PIP2CaPLA2 = ;
  AA = 0;
  APC = 30;
end

model *bi_model_1999_version01____main()

  // Sub-modules, and any changes to those submodules:
  environment: bi_model_1999_version01__environment(t);
  PLA2: bi_model_1999_version01__PLA2(t, CaPLA2, PIP2CaPLA2, PIP2PLA2, DAGCaPLA2, CaPLA2_star);
  AA: bi_model_1999_version01__AA(t, CaPLA2, DAGCaPLA2, CaPLA2_star, PIP2PLA2, PIP2CaPLA2);
end