//Created by libAntimony v2.4 model bi_model_1999_version01__environment(t) // Variable initializations: t = ; end model bi_model_1999_version01__CaIP3(t) // Rate Rules: Ca' = ((-(((Ca_pump * Vmax1 * Ca) / (km1 + Ca) - Extracell_Leak * Ca_ext * p2) - Cap_channel_star * p4 * Ca_ext) + Stores_Leak * Ca_stores * p3 + IP3R_star * Ca_stores * p4) - Ca * Ca * Ca_transp * kf7) + Ca2Ca_transp * kb7; Ca2Ca_transp' = (Ca * Ca * Ca_transp * kf7 - Ca2Ca_transp * kb7) - Ca2Ca_transp * kf6; Ca_stores' = ((- Stores_Leak * Ca_stores * p3 - IP3R_star * Ca_stores * p4) - Ca_stores * Cap_channel_star * kf8) + Cap_channel * kb8 + Ca2Ca_transp * kf6; Ca_transp' = - Ca * Ca * Ca_transp * kf7 + Ca2Ca_transp * kb7 + Ca2Ca_transp * kf6; IP3R' = IP3R_star * kb9 - IP3 * IP3 * IP3 * IP3R * kf9; IP3R_star' = (- IP3R_star * kb9 + IP3 * IP3 * IP3 * IP3R * kf9) - IP3R_star * Ca_stores * p5; IP3' = IP3R_star * kb9 - IP3 * IP3 * IP3 * IP3R * kf9; Ca_ext' = ((Ca_pump * Vmax1 * Ca) / (km1 + Ca) - Extracell_Leak * Ca_ext * p2) - Cap_channel_star * p4 * Ca_ext; Cap_channel' = Ca_stores * Cap_channel_star * kf8 - Cap_channel * kb8; Cap_channel_star' = (- Ca_stores * Cap_channel_star * kf8 + Cap_channel * kb8) - Cap_channel_star * p4 * Ca_ext; // Variable initializations: t = ; km1 = 0.2; Vmax1 = 72; kf6 = 25; kf7 = 0.00000001; kb7 = 144; kf8 = 0.000000000012; kb8 = 1; kf9 = 0.00000000000000000001; kb9 = 1; p2 = 0.004; p3 = 8; p4 = 0.005; p5 = 19.2; Ca = 0.08; Ca2Ca_transp = 0.08; Ca_stores = 6.3328; Stores_Leak = 0.001; Ca_transp = 0.0083838; IP3R = 0.016643; IP3R_star = ; IP3 = ; Ca_pump = 0.00083333; Ca_ext = 4000; Extracell_Leak = 0.00083333; Cap_channel = 0.00083333; Cap_channel_star = ; end model *bi_model_1999_version01____main() // Sub-modules, and any changes to those submodules: environment: bi_model_1999_version01__environment(t); CaIP3: bi_model_1999_version01__CaIP3(t); end