Ik Ica Ikca Ikatp cm n_infinity n tau_n 1 1 vn Vm sn gK n Vm VK 1 1 v Vm sm gCa m_infinity Vm VCa gkCa 1 kd c 2 Vm VK gkATP_ katpo Vm VK topo bottomo 0.08 1 2 mgadp 17 0.89 mgadp 17 2 1 mgadp 17 2 1 adp3m 26 atp4m 1 0.165 adp 0.135 adp 0.05 atp kGPDH FBP 1 JGK_ms JPFK_ms JPFK_ms 0.5 JGPDH 0.3 G6P lambda VmaxPFK topa16 VmaxPFK topb bottom16 kappa JPFK atp 2 k4 1 topa1 bottom1 weight2 topa2 weight3 F6P 2 k3 1 bottom2 weight3 F6P atp 2 f43 k3 k4 1 2 topa3 weight4 bottom3 weight4 FBP k2 topa4 bottom4 weight5 FBP atp 2 k2 k4 f42 1 topa5 bottom5 weight6 FBP F6P 2 k2 k3 f23 1 topa6 weight7 bottom6 weight7 FBP F6P 2 atp 2 k2 k3 k4 f23 f42 f43 1 2 topa7 weight8 bottom7 weight8 AMP k1 topa8 bottom8 weight9 AMP atp 2 k1 k4 f41 1 topa9 bottom9 weight10 AMP F6P 2 k1 k3 f13 1 topa10 weight11 bottom10 weight11 AMP F6P 2 atp 2 k1 k3 k4 f13 f41 f43 1 2 topa11 weight12 bottom11 weight12 AMP FBP k1 k2 topa12 bottom12 weight13 AMP FBP atp 2 k1 k2 k4 f42 f41 1 topa13 bottom13 weight14 AMP FBP F6P 2 k1 k2 k3 f23 f13 1 topa14 bottom14 weight15 AMP FBP F6P 2 atp 2 k1 k2 k3 k4 f23 f13 f42 f41 f43 1 2 topa15 weight16 bottom15 weight16 weight15 p1 p2 NADHm NADm Cam p3 Cam JGPDH JGPDHbas gamma JPDH JO p4 NADHm p5 NADHm 1 delta_psi p6 p7 NADmtot NADHm JHres JHatp JANT JHleak JNaCa 2 Juni Cmito p8 NADHm p9 NADHm 1 delta_psi p10 p11 p16 p13 p13 ATPm 1 p14 delta_psi p15 3 JF1F0 kappa JGK p17 delta_psi p18 p19 RATm RATm p20 -0.5 FRT delta_psi ATPm ADPm p21 delta_psi p22 c 2 p23 c Cam p24 delta_psi fmito Jmito JNaCa Juni gamma JANT JF1F0 Amtot ADPm delta JANT Jhyd khyd c khydbas atp atot adp fcyt Jmem Jer delta Jmito 4.5 -6 alpha Ica kPMCA c Cbas pleak Caer c kSERCA c Jleak JSERCA fer Vc_Ver Jer 3.9 53.2