$\mathrm{V\_IN}-\mathrm{V\_HK}$ $\mathrm{V\_HK}-\mathrm{V\_PFK}+\mathrm{V\_G6PDH}$ $\mathrm{V\_PFK}-\mathrm{V\_ALD}$ $2\mathrm{V\_ALD}-\mathrm{V\_GAPDH}$ $\mathrm{V\_GAPDH}-\mathrm{V\_PGK}$ $\mathrm{V\_PGK}-\mathrm{V\_PK}$ $\mathrm{V\_PK}-\mathrm{V\_TCA}+\mathrm{V\_ADH}$ $\mathrm{V\_PGK}+\mathrm{V\_PK}+\mathrm{PO}\mathrm{V\_TCA}-\mathrm{V\_HK}+\mathrm{V\_PFK}+\mathrm{V\_ATPase}$ $\mathrm{Cn}-\mathrm{ATP}+\mathrm{AMP}$ $\mathrm{CMTP}-\mathrm{CT}+\mathrm{CP}$ $-(\mathrm{kpol}\mathrm{CT}\mathrm{CP}^2+\mathrm{kf}\mathrm{CD}+\mathrm{kb}\mathrm{CT}\mathrm{GDP})$ $\mathrm{kpol}\mathrm{CT}\mathrm{CP}^2-\mathrm{kdp}\mathrm{CP}$ $0.1\mathrm{kp2}\mathrm{PKt}\mathrm{CP}-\mathrm{kp3}\mathrm{PKp}+\mathrm{k4}\mathrm{PKp}\mathrm{GTP}$ $\mathrm{C\_PK}-\mathrm{PKp}$ $\mathrm{V\_IN\_max}(\frac{\mathrm{G\_o}}{(\mathrm{KG\_in}+\mathrm{G\_o})(1+\frac{\mathrm{G6P}}{\mathrm{Ke\_in}})}-\frac{G}{(\mathrm{KG\_in}+G)(1+\frac{\mathrm{G6P}}{\mathrm{Ke\_in}})})$ $\frac{\mathrm{V\_HK\_max}\times 1}{1+\frac{\mathrm{KG\_s}\mathrm{KATP\_m}}{G\mathrm{ATP}}+\frac{\mathrm{KG\_m}}{G}+\frac{\mathrm{KATP\_m}}{\mathrm{ATP}}}$ $\frac{\frac{\frac{\mathrm{V\_PFK\_max}\mathrm{gr}\mathrm{G6P}}{\mathrm{KG6P\_r}}\mathrm{ATP}}{\mathrm{KATP\_r}}(1+\frac{\mathrm{G6P}}{\mathrm{KG6P\_r}}+\frac{\mathrm{ATP}}{\mathrm{KATP\_r}}+\frac{\frac{\mathrm{gr}\mathrm{G6P}}{\mathrm{KG6P\_r}}\mathrm{ATP}}{\mathrm{KATP\_r}})^{(\mathrm{n1}-1)}}{(1+\frac{\mathrm{G6P}}{\mathrm{KG6P\_r}}+\frac{\mathrm{ATP}}{\mathrm{KATP\_r}}+\frac{\frac{\mathrm{gr}\mathrm{G6P}}{\mathrm{KG6P\_r}}\mathrm{ATP}}{\mathrm{KATP\_r}})^{\mathrm{n1}}+\mathrm{Lo}\left(\frac{1+\frac{\mathrm{cAMP}\mathrm{AMP}}{\mathrm{KAMP\_r}}}{1+\frac{\mathrm{AMP}}{\mathrm{KAMP\_r}}}\right)^{\mathrm{n1}}(1+\frac{\mathrm{cG6P}\mathrm{G6P}}{\mathrm{KG6P\_r}}+\frac{\mathrm{cATP}\mathrm{ATP}}{\mathrm{KATP\_r}}+\frac{\frac{\mathrm{gr}\mathrm{cG6P}\mathrm{G6P}}{\mathrm{KG6P\_r}}\mathrm{cATP}\mathrm{ATP}}{\mathrm{KATP\_r}})^{\mathrm{n1}}}$ $\frac{\mathrm{V\_G6PDH\_max}}{\frac{\mathrm{KG6P}\mathrm{KNADP}}{\mathrm{G6P}\mathrm{NADP}}+\frac{\mathrm{KG6P}}{\mathrm{G6P}}+\frac{\mathrm{KNADP}}{\mathrm{NADP}}+1}+\frac{\mathrm{V\_G6PDH\_max\_II}}{\frac{\mathrm{KG6P}\mathrm{KNADP\_}\mathrm{KTUB}}{\mathrm{G6P}\mathrm{NADP}\mathrm{TUB}}+\frac{\mathrm{KG6P}\mathrm{KNADP\_}}{\mathrm{G6P}\mathrm{NADP}}+\frac{\mathrm{KNADP\_}\mathrm{KTUB}}{\mathrm{NADP}\mathrm{TUB}}+\frac{\mathrm{KG6P}\mathrm{KTUB}}{\mathrm{G6P}\mathrm{TUB}}+\frac{\mathrm{KTUB}}{\mathrm{TUB}}+\frac{\mathrm{KG6P}}{\mathrm{G6P}}+\frac{\mathrm{KNADP\_}}{\mathrm{NADP}}+1}$ $\mathrm{CT}+\mathrm{CD}$ $\frac{\frac{\mathrm{V\_ALD\_max}\mathrm{FDP}}{\mathrm{KFDP\_m}}-\frac{\mathrm{V\_ALD\_max\_r}\mathrm{G3P}}{\mathrm{KG3P\_m}}}{1+\frac{\mathrm{FDP}}{\mathrm{KFDP\_m}}+\frac{\mathrm{G3P}}{\mathrm{KG3P\_m}}}$ $\frac{\mathrm{V\_GAPDH\_max}}{1+\frac{\mathrm{KG3P}}{\mathrm{G3P}}+\frac{\mathrm{KNAD}}{\mathrm{NAD}}(1+\frac{\mathrm{AMP}}{\mathrm{K1}}+\frac{\mathrm{ADP}}{\mathrm{K2}}+\frac{\mathrm{ATP}}{\mathrm{K3}})+\frac{\mathrm{KG3P}\mathrm{KNAD}}{\mathrm{G3P}\mathrm{NAD}}(1+\frac{\mathrm{NADH}}{\mathrm{KNADH\_i}})+1+\frac{\mathrm{AMP}}{\mathrm{K1}}+\frac{\mathrm{ADP}}{\mathrm{K2}}+\frac{\mathrm{ATP}}{\mathrm{K3}}}$ $\frac{\mathrm{V\_PGK\_max}\mathrm{DPG}}{\mathrm{KDPG\_m}+\mathrm{DPG}}$ $\frac{\frac{\mathrm{V\_PK\_max}}{1+\frac{\mathrm{KpH}}{H}}(\mathrm{gr\_PK}\frac{\mathrm{PEP}}{\mathrm{KPEP\_r}}\frac{\mathrm{ADP}}{\mathrm{KADP\_r}}R^{(n-1)}+\mathrm{Lo\_PK}\left(\frac{1+\frac{\mathrm{cFDP}\mathrm{FDP}}{\mathrm{KFDP\_r}}}{1+\frac{\mathrm{FDP}}{\mathrm{KFDP\_r}}}\right)^n\frac{\mathrm{FDP}}{\mathrm{KFDP\_r}}\mathrm{gt\_PK}\frac{\mathrm{cPEP}\mathrm{PEP}}{\mathrm{KPEP\_r}}\frac{\mathrm{cADP}\mathrm{ADP}}{\mathrm{KADP\_r}}T^{(n-1)})}{R^n+\mathrm{Lo\_PK}\left(\frac{1+\frac{\mathrm{cFDP}\mathrm{FDP}}{\mathrm{KFDP\_r}}}{1+\frac{\mathrm{FDP}}{\mathrm{KFDP\_r}}}\right)^{n}T^n}$ $1+\frac{\mathrm{PEP}}{\mathrm{KPEP\_r}}+\frac{\mathrm{ADP}}{\mathrm{KADP\_r}}+\frac{\frac{\mathrm{gr\_PK}\mathrm{PEP}}{\mathrm{KPEP\_r}}\mathrm{ADP}}{\mathrm{KADP\_r}}$ $1+\frac{\mathrm{cPEP}\mathrm{PEP}}{\mathrm{KPEP\_r}}+\frac{\mathrm{cADP}\mathrm{ADP}}{\mathrm{KADP\_r}}+\frac{\frac{\mathrm{gt\_PK}\mathrm{cPEP}\mathrm{PEP}}{\mathrm{KPEP\_r}}\mathrm{cADP}\mathrm{ADP}}{\mathrm{KADP\_r}}$ $4+\frac{\mathrm{PKp}}{\mathrm{C\_PK}}$ $\mathrm{V\_PKt\_max}+\frac{(\mathrm{V\_PKp\_max}-\mathrm{V\_PKt\_max})\mathrm{PKp}}{\mathrm{C\_PK}}$ $\frac{\mathrm{V\_TCA\_max}\mathrm{Py}^2}{\mathrm{KPy\_m}^2+\mathrm{Py}^2}$ $\frac{\mathrm{V\_ADH\_max}\mathrm{Py}}{\mathrm{KPy\_\_m}+\mathrm{Py}}$ $\mathrm{KATP}\mathrm{ATP}$