// Created by libAntimony v2.8.0
function Constant_flux__irreversible(v)
  v;
end

function Loss_of_intracellular_choline_0(k1, a, b)
  k1*a*b;
end

function Effect_of_extracellular_ACh_0(k3, a)
  k3*a;
end

function Decrease_in_the_extracellular_concentration_of_beta_amyloid_0(k4, b)
  k4*b;
end


model *MODEL1410200001()

  // Compartments and Species:
  compartment Brain;
  species a in Brain, b in Brain, $aRel in Brain;

  // Assignment Rules:
  aRel := a/50;

  // Reactions:
  Loss_of_intracellular_choline: a => ; Brain*Loss_of_intracellular_choline_0(k1, a, b);
  Abeta_formation_from_APP:  => b; Brain*Constant_flux__irreversible(k2);
  Effect_of_extracellular_ACh: b => ; Brain*Effect_of_extracellular_ACh_0(k3, a);
  Decrease_in_the_extracellular_concentration_of_beta_amyloid: b => ; Brain*Decrease_in_the_extracellular_concentration_of_beta_amyloid_0(k4, b);

  // Species initializations:
  a = 50;
  b = 0;

  // Compartment initializations:
  Brain = 1;

  // Variable initializations:
  k1 = 0.007;
  k2 = 0.33;
  k3 = 0.0042;
  k4 = 0.01;

  // Other declarations:
  const Brain, k1, k2, k3, k4;

  // Unit definitions:
  unit volume = 1e-3 litre;
  unit time_unit = 86400 second;
  unit substance = 1e-3 mole;

  // Display Names:
  time_unit is "time";
  Loss_of_intracellular_choline is "Loss of intracellular choline";
  Abeta_formation_from_APP is "Abeta formation from APP";
  Effect_of_extracellular_ACh is "Effect of extracellular ACh";
  Decrease_in_the_extracellular_concentration_of_beta_amyloid is "Decrease in the extracellular concentration of beta-amyloid";
end