// Created by libAntimony v2.8.0 model *MODEL1403050000() // Compartments and Species: compartment cell; species CD95 in cell, FADD in cell, p55free in cell, Bid in cell, PrNES_mCherry in cell; species PrER_mGFP in cell, DISC in cell, DISCp55 in cell, p30 in cell, p43 in cell; species p18 in cell, p18inactive in cell, tBid in cell, PrNES in cell, mCherry in cell; species PrER in cell, mGFP in cell, CD95L in cell; // Assignment Rules: CD95act := (CD95^3*KDL^2*CD95L)/((CD95L + KDL)*(CD95^2*KDL^2 + KDR*CD95L^2 + 2*KDR*KDL*CD95L + KDR*KDL^2)); // Reactions: reaction_1: FADD => DISC; kon_FADD*CD95act*FADD*cell; reaction_2: DISC => FADD; koff_FADD*DISC*cell; reaction_3: p55free + DISC => DISCp55; kDISC*p55free*DISC*cell; reaction_4: DISCp55 => p30; kD216*DISCp55*cell; reaction_5: p43 => p18 + DISC; kD216*p43*cell; reaction_6: DISCp55 => p43; kD374trans_p55*DISCp55*(DISCp55 + p30)*cell; reaction_7: DISCp55 => p43; kD374trans_p43*DISCp55*p43*cell; reaction_8: p30 => p18 + DISC; kD374trans_p55*p30*(DISCp55 + p30)*cell; reaction_9: p30 => p18 + DISC; kD374trans_p43*p30*p43*cell; reaction_10: p18 => p18inactive; kdiss_p18*p18*cell; reaction_11: Bid => tBid; kBid*Bid*(p43 + p18)*cell; reaction_12: PrNES_mCherry => PrNES + mCherry; kD374probe*PrNES_mCherry*(p43 + p18)*cell; reaction_13: PrER_mGFP => PrER + mGFP; kD374probe*PrER_mGFP*p18*cell; // Species initializations: CD95 = 116; FADD = 93; p55free = 155; Bid = 236; PrNES_mCherry = 973; PrER_mGFP = 5178; DISC = 0; DISCp55 = 0; p30 = 0; p43 = 0; p18 = 0; p18inactive = 0; tBid = 0; PrNES = 0; mCherry = 0; PrER = 0; mGFP = 0; CD95L = 16.6; // Compartment initializations: cell = 1; // Variable initializations: kon_FADD = 0.000811711012144556; koff_FADD = 0.00566528253772301; kDISC = 0.000491828591049766; kD216 = 0.0114186392006403; kD374trans_p55 = 0.000446994772958953; kD374trans_p43 = 0.00343995957326369; kdiss_p18 = 0.0949914492651531; kBid = 0.00052867403363568; kD374probe = 0.00152252549827479; KDR = 8.98496674617627; KDL = 15.421878766215; // Other declarations: var CD95act; const cell, kon_FADD, koff_FADD, kDISC, kD216, kD374trans_p55, kD374trans_p43; const kdiss_p18, kBid, kD374probe, KDR, KDL; end