// Created by libAntimony v2.8.0 model *MODEL1302180006() // Compartments and Species: compartment default, c1; substanceOnly species $s3 in c1, s27 in c1, s45 in c1, s47 in c1, s48 in c1; substanceOnly species s50 in c1, s51 in c1, s52 in c1, s57 in c1, s58 in c1; substanceOnly species s60 in c1, s61 in c1, s62 in c1, s63 in c1, s64 in c1; substanceOnly species s65 in c1, s66 in c1, s116 in c1, s117 in c1, s118 in c1; // Reactions: re37: s51 + s47 => s45; k4*s47*s51; re38: s48 + s51 -> s50; k3*s51*s48 - k3r*s50; re41: s52 -> s48; k1*s3*s52 - k1r*s48; re42: s48 => s47; k2*s3*s48 - k2r*s47; re50: s45 -> s50; k5*s45 - k2*s3*s50; re51: s45 + s57 => s58; k6*s45*s57; re52: s58 -> s61; k5*s58 - k2*s3*s61; re53: s61 => s50 + s57; k7*s61; re54: s60 -> s62; k5*s60 - k2*s3*s62; re55: s58 -> s60; (k10*s58*s27)/(s58 + Km10) - (V10r*s60)/(s60 + Km10r); re56: s61 -> s62; (k10*s61*s27)/(s61 + Km10) - (V10r*s62)/(s62 + Km10r); re69: s63 => s64; re69_kCaM*(s45 + s58) + re69_kp*(s62 + s65) + re69_kpCaM*s60; re70: s65 => s66; (V10r*s65)/(s65 + Km10r); re71: s66 => s51 + s57; k7*s66; re72: s62 -> s65 + s48; k3r*s62 - k3*s65*s48; re131: s51 => s116; kD*s51; re132: s45 => s117 + s47; kD*s45; re133: s50 => s117 + s48; kD*s50; re134: s66 => s57 + s118; kD*s66; re135: s65 => s118 + s57; kD*s65; re136: s61 => s57 + s48; kD*s61; re137: s62 => s57 + s48; kD*s62; re138: s58 => s57 + s47; kD*s58; re139: s60 => s57 + s47; kD*s60; // Species initializations: s3 = 117.2/c1; s3 has substance_per_volume; s27 = 1.723/c1; s27 has substance_per_volume; s45 = 0.0415/c1; s45 has substance_per_volume; s47 = 2.827/c1; s47 has substance_per_volume; s48 = 347.52/c1; s48 has substance_per_volume; s50 = 2.12/c1; s50 has substance_per_volume; s51 = 34.98/c1; s51 has substance_per_volume; s52 = 7635.36/c1; s52 has substance_per_volume; s57 = 199987/c1; s57 has substance_per_volume; s58 = 1.037/c1; s58 has substance_per_volume; s60 = 0.0089/c1; s60 has substance_per_volume; s61 = 10.98/c1; s61 has substance_per_volume; s62 = 0.106/c1; s62 has substance_per_volume; s63 = 500000/c1; s63 has substance_per_volume; s64 = 0; s64 has substance_per_volume; s65 = 0.643/c1; s65 has substance_per_volume; s66 = 0.083/c1; s66 has substance_per_volume; s116 = 0; s116 has substance_per_volume; s117 = 0; s117 has substance_per_volume; s118 = 0; s118 has substance_per_volume; // Compartment initializations: default = 1; default has volume; c1 = 1; c1 has volume; // Variable initializations: k1 = 0.004; k1 has inv_sec_sub; k1r = 10.3; k1r has inv_sec; k2 = 0.08; k2 has inv_sec_sub; k2r = 1152; k2r has inv_sec; k4 = 0.015; k4 has inv_sec_sub; k3 = 0.00015; k3 has inv_sec_sub; k3r = 1.5; k3r has inv_sec; k10 = 0.1; k10 has inv_sec; Km10 = 5; Km10 has substance; Km10r = 20; Km10r has substance; V10r = 4; V10r has sub_sec; k6 = 0.002; k6 has inv_sec_sub; k7 = 1.5; k7 has inv_sec; kD = 9.45e-005; kD has inv_sec; k5 = 115.2; k5 has inv_sec; re69_kCaM = 17; re69_kCaM has inv_sec; re69_kp = 5; re69_kp has inv_sec; re69_kpCaM = 17; re69_kpCaM has inv_sec; // Other declarations: const default, c1, k1, k1r, k2, k2r, k4, k3, k3r, k10, Km10, Km10r, V10r; const k6, k7, kD, k5; // Unit definitions: unit time_unit = second; unit substance = 1e-009 mole; unit area = metre^2; unit length = metre; unit volume = litre; unit sub_sec = 1e-009 mole / second; unit inv_sec = 1 / second; unit inv_sec_sub = 1 / (1e-009 mole * second); unit nM_inv_s = 1e-9 mole / second; unit inv_nM_s = 1 / (1e-9 mole * second); unit substance_per_volume = 1e-009 mole / litre; // Display Names: time_unit is "time"; c1 is "Cell"; s3 is "Ca_c"; s27 is "pp-AKT:PI3P"; s45 is "eNOS-CaM-Ca4"; s47 is "CaM-Ca4"; s48 is "CaM-Ca2"; s50 is "eNOS-CaM-Ca2"; s51 is "eNOS-Cav-1"; s52 is "Calmodulin"; s57 is "Hsp90"; s58 is "Hsp90-eNOS-CaM-Ca4"; s60 is "Hsp90-p-eNOS-CaM-Ca4"; s61 is "Hsp90-eNOS-CaM-Ca2"; s62 is "Hsp90-p-eNOS-CaM-Ca2"; s63 is "L-Arg"; s64 is "NO"; s65 is "Hsp90-p-eNOS"; s66 is "Hsp90-eNOS"; s116 is "sa49_degraded"; end