// Created by libAntimony v2.8.0
model *MODEL1304160000()

  // Compartments and Species:
  compartment cellvolume;
  species IR in cellvolume, IRp in cellvolume, IRins in cellvolume, IRip in cellvolume;
  species IRi in cellvolume, IRS1 in cellvolume, IRS1p in cellvolume, IRS1p307 in cellvolume;
  species IRS1307 in cellvolume, X in cellvolume, Xp in cellvolume, PKB in cellvolume;
  species PKB308p in cellvolume, PKB473p in cellvolume, PKB308p473p in cellvolume;
  species mTORC1 in cellvolume, mTORC1a in cellvolume, mTORC2 in cellvolume;
  species mTORC2a in cellvolume, AS160 in cellvolume, AS160p in cellvolume;
  species GLUT4m in cellvolume, GLUT4 in cellvolume, S6K in cellvolume, S6Kp in cellvolume;
  species S6 in cellvolume, S6p in cellvolume;

  // Assignment Rules:
  measuredIRp := scaleIR*(IRp + IRip);
  measuredIRint := IRi + IRip;
  measuredIRS1p := scaleIRS1*(IRS1p + IRS1p307);
  measuredIRS1307 := scaleIRS1307*(IRS1p307 + IRS1307);
  measuredPKB308p := scalePKB308*(PKB308p + PKB308p473p);
  measuredPKB473p := scalePKB473*(PKB473p + PKB308p473p);
  measuredAS160p := scaleAS160*AS160p;
  measuredmTORC1a := mTORC1a;
  measuredS6Kp := scaleS6K*S6Kp;
  measuredS6p := scaleS6*S6p;
  measuredmTORC2a := mTORC2a;
  glucoseuptake := k8*GLUT4m*gluc + glut1*gluc;

  // Reactions:
  v1a: IR => IRins; IR*k1a*insulin;
  v1basal: IR => IRp; k1basal*IR;
  v1c: IRins => IRp; IRins*k1c;
  v1d: IRp => IRip; IRp*k1d;
  v1e: IRip => IRi; IRip*k1f*Xp;
  v1g: IRp => IR; IRp*k1g;
  v1r: IRi => IR; IRi*k1r;
  v2a: IRS1 => IRS1p; IRS1*k2a*IRip;
  v2b: IRS1p => IRS1; IRS1p*k2b;
  v2c: IRS1p => IRS1p307; IRS1p*k2c*mTORC1a*diabetes;
  v2d: IRS1p307 => IRS1p; IRS1p307*k2d;
  v2f: IRS1p307 => IRS1307; IRS1p307*k2f;
  v2basal: IRS1 => IRS1307; IRS1*k2basal;
  v2g: IRS1307 => IRS1; IRS1307*k2g;
  v3a: X => Xp; X*k3a*IRS1p;
  v3b: Xp => X; Xp*k3b;
  v5a: mTORC1 => mTORC1a; mTORC1*(k5a1*PKB308p473p + k5a2*PKB308p);
  v5b: mTORC1a => mTORC1; mTORC1a*k5b;
  v5c: mTORC2 => mTORC2a; mTORC2*k5c*IRip;
  v5d: mTORC2a => mTORC2; k5d*mTORC2a;
  v4a: PKB => PKB308p; k4a*PKB*IRS1p;
  v4b: PKB308p => PKB; k4b*PKB308p;
  v4c: PKB308p => PKB308p473p; k4c*PKB308p*mTORC2a;
  v4e: PKB473p => PKB308p473p; k4e*PKB473p*IRS1p307;
  v4f: PKB308p473p => PKB473p; k4f*PKB308p473p;
  v4h: PKB473p => PKB; k4h*PKB473p;
  v6f1: AS160 => AS160p; AS160*(k6f1*PKB308p473p + (k6f2*PKB473p^n6)/(km6^n6 + PKB473p^n6));
  v6b1: AS160p => AS160; AS160p*k6b;
  v7f: GLUT4 => GLUT4m; GLUT4*k7f*AS160p;
  v7b: GLUT4m => GLUT4; GLUT4m*k7b;
  v9f1: S6K => S6Kp; (S6K*k9f1*mTORC1a^n9)/(km9^n9 + mTORC1a^n9);
  v9b1: S6Kp => S6K; S6Kp*k9b1;
  v9f2: S6 => S6p; S6*k9f2*S6Kp;
  v9b2: S6p => S6; S6p*k9b2;

  // Species initializations:
  IR = 49.9344643421136;
  IRp = 0.000931221500588088;
  IRins = 0;
  IRip = 0.011815001204792;
  IRi = 0.0527894351383809;
  IRS1 = 86.2418960059256;
  IRS1p = 0.00095272377217019;
  IRS1p307 = 0.00891531075576947;
  IRS1307 = 13.7482359094757;
  X = 99.9986712896423;
  Xp = 0.00132871035763352;
  PKB = 78.0219322115859;
  PKB308p = 12.2197372437326;
  PKB473p = 9.6963389945784;
  PKB308p473p = 0.061992532897245;
  mTORC1 = 96.927052256569;
  mTORC1a = 3.07294774343092;
  mTORC2 = 99.9045223943705;
  mTORC2a = 0.0954776056294795;
  AS160 = 95.4699007486273;
  AS160p = 4.53009925137289;
  GLUT4m = 4.5880858350243;
  GLUT4 = 45.4119141649757;
  S6K = 99.8296860066098;
  S6Kp = 0.170313993390069;
  S6 = 98.2037625421647;
  S6p = 1.79623745783512;

  // Compartment initializations:
  cellvolume = 1;

  // Variable initializations:
  diabetes = 0.15;
  k1a = 0.6331;
  k1basal = 0.03683;
  k1c = 0.8768;
  k1d = 31.01;
  k1f = 1840;
  k1g = 1944;
  k1r = 0.5471;
  k2a = 3.227;
  k2c = 5759;
  k2basal = 0.04228;
  k2b = 3424;
  k2d = 280.8;
  k2f = 2.913;
  k2g = 0.2671;
  k3a = 0.001377;
  k3b = 0.09876;
  k4a = 5790;
  k4b = 34.8;
  k4c = 4.456;
  k4e = 42.84;
  k4f = 143.6;
  k4h = 0.5361;
  k5a1 = 1.842;
  k5a2 = 0.05506;
  k5b = 24.83;
  k5d = 1.06;
  km5 = 2.65;
  k5c = 0.08575;
  k6f1 = 2.652;
  k6f2 = 36.93;
  km6 = 30.54;
  n6 = 2.137;
  k6b = 65.18;
  k7f = 50.98;
  k7b = 2286;
  k8 = 724.2;
  glut1 = 7042;
  k9f1 = 0.1298;
  k9b1 = 0.04441;
  k9f2 = 3.329;
  k9b2 = 31;
  km9 = 5873;
  n9 = 0.9855;
  scaleIR = 5.202;
  scaleIRS1 = 0.3761;
  scaleIRS1ds = 14.89;
  scaleIRS1307 = 0.05866;
  scalePKB308 = 0.04356;
  scalePKB473 = 0.013;
  scaleAS160 = 0.026656;
  scaleGLUCOSE = 0.04051;
  scaleS6K = 0.7465;
  scaleS6 = 0.1149;
  gluc = 0.05;
  insulin = 10;

  // Other declarations:
  var measuredIRp, measuredIRint, measuredIRS1p, measuredIRS1307, measuredPKB308p;
  var measuredPKB473p, measuredAS160p, measuredmTORC1a, measuredS6Kp, measuredS6p;
  var measuredmTORC2a, glucoseuptake;
  const cellvolume, diabetes, k1a, k1basal, k1c, k1d, k1f, k1g, k1r, k2a;
  const k2c, k2basal, k2b, k2d, k2f, k2g, k3a, k3b, k4a, k4b, k4c, k4e, k4f;
  const k4h, k5a1, k5a2, k5b, k5d, km5, k5c, k6f1, k6f2, km6, n6, k6b, k7f;
  const k7b, k8, glut1, k9f1, k9b1, k9f2, k9b2, km9, n9, scaleIR, scaleIRS1;
  const scaleIRS1ds, scaleIRS1307, scalePKB308, scalePKB473, scaleAS160, scaleGLUCOSE;
  const scaleS6K, scaleS6, gluc, insulin;
end