// Created by libAntimony v2.8.0 model *MODEL1212040001() // Compartments and Species: compartment compartment_; species R in compartment_, L in compartment_, RL in compartment_, Gabg in compartment_; species RGabg in compartment_, RGabgL in compartment_, GaGTP in compartment_; species Gbg in compartment_, RGS in compartment_, RGSGaGTP in compartment_; species GaGDPP in compartment_, Effector in compartment_, GaGTPEffector in compartment_; species inertGaGTP in compartment_, RGSinertGaGTP in compartment_, GaGDP in compartment_; species P in compartment_, z1 in compartment_, z2 in compartment_, z3 in compartment_; // Reactions: R1: R + L => RL; compartment_*R*L*R1_k1; R2: R + Gabg => RGabg; compartment_*R*Gabg*R2_k2; R3: RL + Gabg => RGabgL; compartment_*RL*Gabg*R3_k3; R4: RGabg + L => RGabgL; compartment_*RGabg*L*R4_k4; R5: RGabgL => RL + GaGTP + Gbg; compartment_*RGabgL*R5_k5; R6: Gabg => GaGTP + Gbg; compartment_*Gabg*R6_k6; R7: GaGTP + RGS => RGSGaGTP; compartment_*GaGTP*RGS*R7_k7; R8: RGSGaGTP => GaGDPP + RGS; compartment_*RGSGaGTP*R8_k8; R9: GaGTP => GaGDPP; compartment_*GaGTP*R9_k9; R10: Effector + GaGTP => GaGTPEffector; compartment_*Effector*GaGTP*R10_k10; R11: GaGTPEffector => inertGaGTP + Effector; compartment_*GaGTPEffector*R11_k11; R12: inertGaGTP + RGS => RGSinertGaGTP; compartment_*inertGaGTP*RGS*R12_k12; R13: RGSinertGaGTP => GaGDPP + RGS; compartment_*RGSinertGaGTP*R13_k13; R14: inertGaGTP => GaGDPP; compartment_*inertGaGTP*R14_k14; R15: GaGDPP => GaGDP + P; compartment_*GaGDPP*R15_k15; R16: GaGDP + Gbg => Gabg; compartment_*GaGDP*Gbg*R16_k16; R17: P => ; compartment_*P*R17_k17; R18: => z1; compartment_*GaGTPEffector*ka; R19: z1 => z2; compartment_*z1*ka; R20: z2 => z3; compartment_*z2*ka; R21: z3 => ; compartment_*z3*ka; // Events: Ligand_addition: at time >= 14: L = L + Ligand_conc; // Species initializations: R = 205; R has nanoMolar; L = 0; L has nanoMolar; RL = 0; RL has nanoMolar; Gabg = 0; Gabg has nanoMolar; RGabg = 0; RGabg has nanoMolar; RGabgL = 0; RGabgL has nanoMolar; GaGTP = 0; GaGTP has nanoMolar; Gbg = 205; Gbg has nanoMolar; RGS = 60; RGS has nanoMolar; RGSGaGTP = 0; RGSGaGTP has nanoMolar; GaGDPP = 0; GaGDPP has nanoMolar; Effector = 205; Effector has nanoMolar; GaGTPEffector = 0; GaGTPEffector has nanoMolar; inertGaGTP = 0; inertGaGTP has nanoMolar; RGSinertGaGTP = 0; RGSinertGaGTP has nanoMolar; GaGDP = 205; GaGDP has nanoMolar; P = 0; P has nanoMolar; z1 = 0; z1 has nanoMolar; z2 = 0; z2 has nanoMolar; z3 = 0; z3 has nanoMolar; // Compartment initializations: compartment_ = 1; // Variable initializations: Ligand_conc = 0.1; Ligand_conc has nanoMolar; ka = 1.5; ka has FirstOrder; R1_k1 = 0.0025; R1_k1 has SecondOrder; R2_k2 = 0.005; R2_k2 has SecondOrder; R3_k3 = 0.02; R3_k3 has SecondOrder; R4_k4 = 0.005; R4_k4 has SecondOrder; R5_k5 = 50; R5_k5 has FirstOrder; R6_k6 = 0.2; R6_k6 has FirstOrder; R7_k7 = 500; R7_k7 has SecondOrder; R8_k8 = 2.5; R8_k8 has FirstOrder; R9_k9 = 0.005; R9_k9 has FirstOrder; R10_k10 = 10; R10_k10 has SecondOrder; R11_k11 = 1; R11_k11 has FirstOrder; R12_k12 = 50; R12_k12 has SecondOrder; R13_k13 = 0.3; R13_k13 has FirstOrder; R14_k14 = 0.005; R14_k14 has FirstOrder; R15_k15 = 1000; R15_k15 has FirstOrder; R16_k16 = 1000; R16_k16 has SecondOrder; R17_k17 = 10; R17_k17 has FirstOrder; // Other declarations: const compartment_, Ligand_conc, ka; // Unit definitions: unit nanoMolar = 1e-9 mole / litre; unit hour = 3600 second; unit FirstOrder = 1 / 3600 second; unit SecondOrder = litre / (1e-9 mole * 3600 second); unit nanoMolar_volume = 1e-9 mole; // Display Names: nanoMolar is "nM"; hour is "hr"; FirstOrder is "1/hr"; SecondOrder is "1/(nM*hr)"; compartment_ is "cell"; R1 is "Receptor-Ligand association"; R2 is "Receptor-Gprotein association"; R3 is "RL-Gprotein association"; R4 is "RGabg-Ligand association"; R5 is "Galpha activation by receptor"; R6 is "Galpha activation spontaneous"; R7 is "Galpha-RGS association"; R8 is "Galpha deactivation by RGS"; R9 is "Galpha deactivation spontaneous"; R10 is "Galpha-Effector association"; R11 is "Galpha becomes inert"; R12 is "inertGalpha-RGS association"; R13 is "inertGalpha deactivation by RGS"; R14 is "inertGalpha deactivation spontaneous"; R15 is "Phosphate release"; R16 is "Gprotein subunits association"; R17 is "Phosphate degradation"; R18 is "Delay 1"; R19 is "Delay 2"; R20 is "Delay 3"; R21 is "Delay 4"; end