// Created by libAntimony v2.8.0 model *Deineko2003_CellCycle() // Compartments and Species: compartment compartment_; species y1 in compartment_, y2 in compartment_, y3 in compartment_, y4 in compartment_; species y5 in compartment_, y6 in compartment_; // Assignment Rules: F6 := piecewise(0.044, time <= 60, 0); // Reactions: R1: => y1; (emax*k1*y1)/(k1*y1 + (k1_prime + k1_double_prime*y1)*y2); R2: y1 => ; phi1*y1; R3: => y2; k2*y1; R4: y2 => y3; k3*y2*y5; R5: y2 => ; phi2*y2; R6: y3 => ; phi3*y3; R7: => y4; k4*y1; R8: => y4; k4_double_prime*y6; R9: y4 => y5; k4i*y4*y5; R10: y5 => y4; k4a*y5; R11: y4 => ; phi4i*y4; R12: y5 => ; phi4a*y5; R13: => y6; k6*y1; R14: => y6; F6; R15: y6 => ; phi6*y6; // Species initializations: y1 = 0.014; y2 = 0.006; y3 = 0; y4 = 0; y5 = 0.0001; y6 = 0; // Compartment initializations: compartment_ = 1; // Variable initializations: emax = 2; k1 = 1; k1_prime = 1; k1_double_prime = 10; phi1 = 0.1; k2 = 1; k3 = 0.4; phi2 = 0.01; phi3 = 0.1; k4 = 0.09; k4_double_prime = 0.1; k4i = 1; k4a = 2; phi4i = 0.01; phi4a = 0.01; k6 = 0; phi6 = 0.1; // Other declarations: var F6; const compartment_, emax, k1, k1_prime, k1_double_prime, phi1, k2, k3, phi2; const phi3, k4, k4_double_prime, k4i, k4a, phi4i, phi4a, k6, phi6; // Display Names: y1 is "E2F"; y2 is "pRB"; y3 is "Phosphorylated pRB"; y4 is "inactive cycE_cdk2"; y5 is "active cycE_cdk2"; y6 is "AP-1"; end