// Created by libAntimony v2.8.0 model *model_0000001() // Compartments and Species: compartment Spine; species D in Spine, CDK5 in Spine, D_CDK5 in Spine, D75 in Spine, CK1 in Spine; species D_CK1 in Spine, D137 in Spine, PKA in Spine, D_PKA in Spine, D34 in Spine; species D34_CDK5 in Spine, D34_CK1 in Spine, PP2B in Spine, D34_PP2B in Spine; species D34_75 in Spine, D34_137 in Spine, D75CK1 in Spine, D75_PKA in Spine; species PP2A in Spine, D75_PP2A in Spine, PP2AP in Spine, D75_PP2AP in Spine; species D75_137 in Spine, D137_CDK5 in Spine, D137_PKA in Spine, D137_PP2C in Spine; species PP2C in Spine, D34_75_CK1 in Spine, D34_137_CDK5 in Spine, D34_75_137 in Spine; species D75_137_PKA in Spine, D34_75_PP2B in Spine, D34_137_PP2B in Spine; species D34_75_137_PP2B in Spine, D34_75_PP2A in Spine, D75_137_PP2A in Spine; species D34_75_134_PP2A in Spine, D34_75_PP2AP in Spine, D75_137_PP2AP in Spine; species D34_75_137_PP2AP in Spine, D34_137_PP2C in Spine, D75_137_PP2C in Spine; species PDE in Spine, PP2Binactive in Spine, D34_75_137_PP2C in Spine, CK1P in Spine; species CK1P_PP2B in Spine, PDE_PKA in Spine, PDEP in Spine, PP2A_PKA in Spine; species Ca in Spine, PP2BinactiveCa2 in Spine, R2C2 in Spine, cAMP in Spine; species cAMP_R2C2 in Spine, cAMP2_R2C2 in Spine, cAMP3_R2C2 in Spine, cAMP4_R2C2 in Spine; species cAMP4_R2C in Spine, cAMP4_R2 in Spine, cAMP_PDE in Spine, AMP in Spine; species cAMP_PDEP in Spine, $Empty in Spine; // Reactions: von1: D + CDK5 => D_CDK5; Spine*von1_kon1*D*CDK5; voff1: D_CDK5 => D + CDK5; Spine*D_CDK5*voff1_koff1; vcat1: D_CDK5 => D75 + CDK5; Spine*D_CDK5*vcat1_kcat1; von2: D + CK1 => D_CK1; Spine*D*CK1*von2_kon2; voff2: D_CK1 => D + CK1; Spine*voff2_koff2*D_CK1; vcat2: D_CK1 => D137 + CK1; Spine*vcat2_kcat2*D_CK1; von3: D + PKA => D_PKA; Spine*D*PKA*von3_kon3; voff3: D_PKA => D + PKA; Spine*D_PKA*voff3_koff3; vcat3: D_PKA => D34 + PKA; Spine*D_PKA*vcat3_kcat3; von4: D34 + CDK5 => D34_CDK5; Spine*D34*CDK5*von4_kon4; von5: D34 + CK1 => D34_CK1; Spine*D34*CK1*von5_kon5; von6: D34 + PP2B => D34_PP2B; Spine*D34*PP2B*von6_kon6; voff4: D34_CDK5 => D34 + CDK5; Spine*D34_CDK5*voff4_koff4; vcat4: D34_CDK5 => D34_75 + CDK5; Spine*D34_CDK5*vcat4_kcat4; voff5: D34_CK1 => D34 + CK1; Spine*D34_CK1*voff5_koff5; vcat5: D34_CK1 => D34_137 + CK1; Spine*D34_CK1*vcat5_kcat5; vcat6: D34_PP2B => D + PP2B; Spine*D34_PP2B*vcat6_kcat6; voff6: D34_PP2B => D34 + PP2B; Spine*D34_PP2B*voff6_koff6; von7: D75 + CK1 => D75CK1; Spine*D75*CK1*von7_kon7; von8: D75 + PKA => D75_PKA; Spine*D75*PKA*von8_kon8; von9: D75 + PP2A => D75_PP2A; Spine*D75*PP2A*von9_kon9; von10: D75 + PP2AP => D75_PP2AP; Spine*D75*PP2AP*von10_kon10; voff7: D75CK1 => D75 + CK1; Spine*D75CK1*voff7_koff7; vcat7: D75CK1 => CK1 + D75_137; Spine*D75CK1*vcat7_kcat7; vcat8: D75_PKA => D34_75 + PKA; Spine*D75_PKA*vcat8_kcat8; voff8: D75_PKA => D75 + PKA; Spine*D75_PKA*voff8_koff8; vcat9: D75_PP2A => D + PP2A; Spine*D75_PP2A*vcat9_kcat9; voff9: D75_PP2A => D75 + PP2A; Spine*D75_PP2A*voff9_koff9; vcat10: D75_PP2AP => D + PP2AP; Spine*D75_PP2AP*vcat10_kcat10; voff10: D75_PP2AP => D75 + PP2AP; Spine*D75_PP2AP*voff10_koff10; von11: D137 + CDK5 => D137_CDK5; Spine*D137*CDK5*von11_kon11; von12: D137 + PKA => D137_PKA; Spine*D137*PKA*von12_kon12; von13: D137 + PP2C => D137_PP2C; Spine*D137*PP2C*von13_kon13; voff11: D137_CDK5 => D137 + CDK5; Spine*D137_CDK5*voff11_koff11; vcat11: D137_CDK5 => D75_137 + CDK5; Spine*D137_CDK5*vcat11_kcat11; voff12: D137_PKA => D137 + PKA; Spine*D137_PKA*voff12_koff12; vcat12: D137_PKA => D34_137 + PKA; Spine*D137_PKA*vcat12_kcat12; vcat13: D137_PP2C => D + PP2C; Spine*D137_PP2C*vcat13_kcat13; voff13: D137_PP2C => D137 + PP2C; Spine*D137_PP2C*voff13_koff13; von14: D34_75 + CK1 => D34_75_CK1; Spine*D34_75*CK1*von14_kon14; von18: D34_137 + CDK5 => D34_137_CDK5; Spine*D34_137*CDK5*von18_kon18; voff18: D34_137_CDK5 => D34_137 + CDK5; Spine*D34_137_CDK5*voff18_koff18; voff14: D34_75_CK1 => D34_75 + CK1; Spine*D34_75_CK1*voff14_koff14; vcat14: D34_75_CK1 => D34_75_137 + CK1; Spine*D34_75_CK1*vcat14_kcat14; vcat18: D34_137_CDK5 => D34_75_137 + CDK5; Spine*D34_137_CDK5*vcat18_kcat18; von21: D75_137 + PKA => D75_137_PKA; Spine*D75_137*PKA*von21_kon21; vcat21: D75_137_PKA => D34_75_137 + PKA; Spine*D75_137_PKA*vcat21_kcat21; voff21: D75_137_PKA => D75_137 + PKA; Spine*D75_137_PKA*voff21_koff21; von17: D34_75 + PP2B => D34_75_PP2B; Spine*D34_75*PP2B*von17_kon17; voff17: D34_75_PP2B => D34_75 + PP2B; Spine*D34_75_PP2B*voff17_koff17; vcat17: D34_75_PP2B => D75 + PP2B; Spine*D34_75_PP2B*vcat17_kcat17; von19: D34_137 + PP2B => D34_137_PP2B; Spine*D34_137*PP2B*von19_kon19; vcat19: D34_137_PP2B => D137 + PP2B; Spine*D34_137_PP2B*vcat19_kcat19; voff19: D34_137_PP2B => D34_137 + PP2B; Spine*D34_137_PP2B*voff19_koff19; von27: D34_75_137 + PP2B => D34_75_137_PP2B; Spine*D34_75_137*PP2B*von27_kon27; voff27: D34_75_137_PP2B => D34_75_137 + PP2B; Spine*D34_75_137_PP2B*voff27_koff27; vcat27: D34_75_137_PP2B => D75_137 + PP2B; Spine*D34_75_137_PP2B*vcat27_kcat27; von15: D34_75 + PP2A => D34_75_PP2A; Spine*D34_75*PP2A*von15_kon15; vcat15: D34_75_PP2A => D34 + PP2A; Spine*D34_75_PP2A*vcat15_kcat15; voff15: D34_75_PP2A => D34_75 + PP2A; Spine*D34_75_PP2A*voff15_koff15; von22: D75_137 + PP2A => D75_137_PP2A; Spine*D75_137*PP2A*von22_kon22; vcat22: D75_137_PP2A => D137 + PP2A; Spine*D75_137_PP2A*vcat22_kcat22; voff22: D75_137_PP2A => D75_137 + PP2A; Spine*D75_137_PP2A*voff22_koff22; von25: D34_75_137 + PP2A => D34_75_134_PP2A; Spine*D34_75_137*PP2A*von25_kon25; vcat25: D34_75_134_PP2A => D34_137 + PP2A; Spine*D34_75_134_PP2A*vcat25_kcat25; voff25: D34_75_134_PP2A => D34_75_137 + PP2A; Spine*D34_75_134_PP2A*voff25_koff25; von16: D34_75 + PP2AP => D34_75_PP2AP; Spine*D34_75*PP2AP*von16_kon16; vcat16: D34_75_PP2AP => D34 + PP2AP; Spine*D34_75_PP2AP*vcat16_kcat16; voff16: D34_75_PP2AP => D34_75 + PP2AP; Spine*D34_75_PP2AP*voff16_koff16; von23: D75_137 + PP2AP => D75_137_PP2AP; Spine*D75_137*PP2AP*von23_kon23; vcat23: D75_137_PP2AP => D137 + PP2AP; Spine*D75_137_PP2AP*vcat23_kcat23; voff23: D75_137_PP2AP => D75_137 + PP2AP; Spine*D75_137_PP2AP*voff23_koff23; vcat26: D34_75_137_PP2AP => D34_137 + PP2AP; Spine*D34_75_137_PP2AP*vcat26_kcat26; von26: D34_75_137 + PP2AP => D34_75_137_PP2AP; Spine*D34_75_137*PP2AP*von26_kon26; voff26: D34_75_137_PP2AP => D34_75_137 + PP2AP; Spine*D34_75_137_PP2AP*voff26_koff26; von20: D34_137 + PP2C => D34_137_PP2C; Spine*D34_137*PP2C*von20_kon20; vcat20: D34_137_PP2C => D34 + PP2C; Spine*D34_137_PP2C*vcat20_kcat20; voff20: D34_137_PP2C => D34_137 + PP2C; Spine*D34_137_PP2C*voff20_koff20; von24: D75_137 + PP2C => D75_137_PP2C; Spine*D75_137*PP2C*von24_kon24; vcat24: D75_137_PP2C => D75 + PP2C; Spine*D75_137_PP2C*vcat24_kcat24; voff24: D75_137_PP2C => D75_137 + PP2C; Spine*D75_137_PP2C*voff24_koff24; von28: D34_75_137 + PP2C => D34_75_137_PP2C; Spine*D34_75_137*PP2C*von28_kon28; vcat28: D34_75_137_PP2C => D34_75 + PP2C; Spine*D34_75_137_PP2C*vcat28_kcat28; voff28: D34_75_137_PP2C => D34_75_137 + PP2C; Spine*D34_75_137_PP2C*voff28_koff28; von29: CK1P + PP2B => CK1P_PP2B; Spine*CK1P*PP2B*von29_kon29; voff29: CK1P_PP2B => CK1P + PP2B; Spine*CK1P_PP2B*voff29_koff29; vcat29: CK1P_PP2B => CK1 + PP2B; Spine*CK1P_PP2B*vcat29_kcat29; vcat30: CK1 => CK1P; Spine*CK1*vcat30_kcat30; von31: PDE + PKA => PDE_PKA; Spine*PDE*PKA*von31_kon31; vcat31: PDE_PKA => PDEP + PKA; Spine*PDE_PKA*vcat31_kcat31; voff31: PDE_PKA => PDE + PKA; Spine*PDE_PKA*voff31_koff31; vcat32: PDEP => PDE; Spine*PDEP*vcat32_kcat32; von33: PP2A + PKA => PP2A_PKA; Spine*PP2A*PKA*von33_kon33; voff33: PP2A_PKA => PP2A + PKA; Spine*PP2A_PKA*voff33_koff33; vcat33: PP2A_PKA => PP2AP + PKA; Spine*PP2A_PKA*vcat33_kcat33; vcat34: PP2AP => PP2A; Spine*PP2AP*vcat34_kcat34; von35: PP2Binactive + 2Ca => PP2BinactiveCa2; Spine*PP2Binactive*Ca*Ca*von35_kon35; von36: PP2BinactiveCa2 + 2Ca => PP2B; Spine*PP2BinactiveCa2*Ca*Ca*von36_kon36; voff35: PP2BinactiveCa2 => PP2Binactive + 2Ca; Spine*PP2BinactiveCa2*voff35_koff35; voff36: PP2B => PP2BinactiveCa2 + 2Ca; Spine*PP2B*voff36_koff36; von37: R2C2 + cAMP => cAMP_R2C2; Spine*R2C2*cAMP*von37_kon37; von38: cAMP_R2C2 + cAMP => cAMP2_R2C2; Spine*cAMP_R2C2*cAMP*von38_kon38; von39: cAMP2_R2C2 + cAMP => cAMP3_R2C2; Spine*cAMP2_R2C2*cAMP*von39_kon39; von40: cAMP3_R2C2 + cAMP => cAMP4_R2C2; Spine*cAMP3_R2C2*cAMP*von40_kon40; voff37: cAMP_R2C2 => R2C2 + cAMP; Spine*cAMP_R2C2*voff37_koff37; voff38: cAMP2_R2C2 => cAMP_R2C2 + cAMP; Spine*cAMP2_R2C2*voff38_koff38; voff39: cAMP3_R2C2 => cAMP2_R2C2 + cAMP; Spine*cAMP3_R2C2*voff39_koff39; voff40: cAMP4_R2C2 => cAMP3_R2C2 + cAMP; Spine*cAMP4_R2C2*voff40_koff40; von41: cAMP4_R2C + PKA => cAMP4_R2C2; Spine*cAMP4_R2C*PKA*von41_kon41; voff41: cAMP4_R2C2 => cAMP4_R2C + PKA; Spine*cAMP4_R2C2*voff41_koff41; von42: cAMP4_R2 + PKA => cAMP4_R2C; Spine*cAMP4_R2*PKA*von42_kon42; von43: cAMP4_R2C => cAMP4_R2 + PKA; Spine*cAMP4_R2C*von43_kon43; von44: cAMP + PDE => cAMP_PDE; Spine*cAMP*PDE*von44_kon44; voff44: cAMP_PDE => cAMP + PDE; Spine*cAMP_PDE*voff44_koff44; vcat44: cAMP_PDE => AMP + PDE; Spine*cAMP_PDE*vcat44_kcat44; von45: cAMP + PDEP => cAMP_PDEP; Spine*cAMP*PDEP*von45_kon45; voff45: cAMP_PDEP => cAMP + PDEP; Spine*cAMP_PDEP*voff45_koff45; vcat45: cAMP_PDEP => AMP + PDEP; Spine*cAMP_PDEP*vcat45_kcat45; v57: $Empty => Ca; Spine*k57; v58: Ca => $Empty; Spine*Ca*v58_k58; // Events: cAMP_pulse: at time >= cAMP_delay: cAMP = 6.600000e-006; ca_on1: at time >= cAMP_delay + cAMP_Ca_delay: k57 = kon_high; ca_on2: at time >= cAMP_delay + cAMP_Ca_delay + 1*(spike_duration + spike_interval): k57 = kon_high; ca_off1: at time >= cAMP_delay + cAMP_Ca_delay + spike_duration: k57 = kon_low; Ca_on3: at time >= cAMP_delay + cAMP_Ca_delay + 2*(spike_duration + spike_interval): k57 = kon_high; ca_on4: at time >= cAMP_delay + cAMP_Ca_delay + 3*(spike_duration + spike_interval): k57 = kon_high; ca_on5: at time >= cAMP_delay + cAMP_Ca_delay + 4*(spike_duration + spike_interval): k57 = kon_high; ca_on6: at time >= cAMP_delay + cAMP_Ca_delay + 5*(spike_duration + spike_interval): k57 = kon_high; ca_on7: at time >= cAMP_delay + cAMP_Ca_delay + 6*(spike_duration + spike_interval): k57 = kon_high; ca_on8: at time >= cAMP_delay + cAMP_Ca_delay + 7*(spike_duration + spike_interval): k57 = kon_high; ca_on9: at time >= cAMP_delay + cAMP_Ca_delay + 8*(spike_duration + spike_interval): k57 = kon_high; ca_on10: at time >= cAMP_delay + cAMP_Ca_delay + 9*(spike_duration + spike_interval): k57 = kon_high; ca_off2: at time >= cAMP_delay + cAMP_Ca_delay + spike_duration + 1*(spike_interval + spike_duration): k57 = kon_low; ca_off3: at time >= cAMP_delay + cAMP_Ca_delay + spike_duration + 2*(spike_interval + spike_duration): k57 = kon_low; ca_off4: at time >= cAMP_delay + cAMP_Ca_delay + spike_duration + 3*(spike_interval + spike_duration): k57 = kon_low; ca_off5: at time >= cAMP_delay + cAMP_Ca_delay + spike_duration + 4*(spike_interval + spike_duration): k57 = kon_low; ca_off6: at time >= cAMP_delay + cAMP_Ca_delay + spike_duration + 5*(spike_interval + spike_duration): k57 = kon_low; ca_off7: at time >= cAMP_delay + cAMP_Ca_delay + spike_duration + 6*(spike_interval + spike_duration): k57 = kon_low; ca_off8: at time >= cAMP_delay + cAMP_Ca_delay + spike_duration + 7*(spike_interval + spike_duration): k57 = kon_low; ca_off9: at time >= cAMP_delay + cAMP_Ca_delay + spike_duration + 8*(spike_interval + spike_duration): k57 = kon_low; ca_off10: at time >= cAMP_delay + cAMP_Ca_delay + spike_duration + 9*(spike_interval + spike_duration): k57 = kon_low; // Species initializations: D = 4.98e-006; CDK5 = 2e-007; D_CDK5 = 0; D75 = 0; CK1 = 1.66e-007; D_CK1 = 0; D137 = 0; PKA = 0; D_PKA = 0; D34 = 0; D34_CDK5 = 0; D34_CK1 = 0; PP2B = 0; D34_PP2B = 0; D34_75 = 0; D34_137 = 0; D75CK1 = 0; D75_PKA = 0; PP2A = 2e-007; D75_PP2A = 0; PP2AP = 0; D75_PP2AP = 0; D75_137 = 0; D137_CDK5 = 0; D137_PKA = 0; D137_PP2C = 0; PP2C = 1.33e-007; D34_75_CK1 = 0; D34_137_CDK5 = 0; D34_75_137 = 0; D75_137_PKA = 0; D34_75_PP2B = 0; D34_137_PP2B = 0; D34_75_137_PP2B = 0; D34_75_PP2A = 0; D75_137_PP2A = 0; D34_75_134_PP2A = 0; D34_75_PP2AP = 0; D75_137_PP2AP = 0; D34_75_137_PP2AP = 0; D34_137_PP2C = 0; D75_137_PP2C = 0; PDE = 2e-006; PP2Binactive = 3.32e-007; D34_75_137_PP2C = 0; CK1P = 0; CK1P_PP2B = 0; PDE_PKA = 0; PDEP = 0; PP2A_PKA = 0; Ca = 0; PP2BinactiveCa2 = 0; R2C2 = 6.64e-006; cAMP = 0; cAMP_R2C2 = 0; cAMP2_R2C2 = 0; cAMP3_R2C2 = 0; cAMP4_R2C2 = 0; cAMP4_R2C = 0; cAMP4_R2 = 0; cAMP_PDE = 0; AMP = 0; cAMP_PDEP = 0; Empty = 0; // Compartment initializations: Spine = 1e-015; // Variable initializations: cAMP_delay = 400; cAMP_Ca_delay = 50; k57 = 2.5e-008; kon_high = 6.6e-006; spike_duration = 2; spike_interval = 2; kon_low = 2.5e-008; von1_kon1 = 5600000; voff1_koff1 = 12; vcat1_kcat1 = 3; von2_kon2 = 4400000; voff2_koff2 = 12; vcat2_kcat2 = 3; von3_kon3 = 5600000; voff3_koff3 = 10.8; vcat3_kcat3 = 2.7; von4_kon4 = 5600000; von5_kon5 = 4400000; von6_kon6 = 10000000; voff4_koff4 = 12; vcat4_kcat4 = 3; voff5_koff5 = 12; vcat5_kcat5 = 3; vcat6_kcat6 = 4; voff6_koff6 = 16; von7_kon7 = 4400000; von8_kon8 = 5600000; von9_kon9 = 3800000; von10_kon10 = 17000000; voff7_koff7 = 12; vcat7_kcat7 = 3; vcat8_kcat8 = 0; voff8_koff8 = 10.8; vcat9_kcat9 = 10; voff9_koff9 = 24; vcat10_kcat10 = 24; voff10_koff10 = 40; von11_kon11 = 5600000; von12_kon12 = 5600000; von13_kon13 = 7500000; voff11_koff11 = 12; vcat11_kcat11 = 3; voff12_koff12 = 10.8; vcat12_kcat12 = 2.7; vcat13_kcat13 = 3; voff13_koff13 = 12; von14_kon14 = 4400000; von18_kon18 = 5600000; voff18_koff18 = 12; voff14_koff14 = 12; vcat14_kcat14 = 3; vcat18_kcat18 = 3; von21_kon21 = 5600000; vcat21_kcat21 = 0; voff21_koff21 = 10.8; von17_kon17 = 10000000; voff17_koff17 = 1600; vcat17_kcat17 = 4; von19_kon19 = 75000; vcat19_kcat19 = 0.03; voff19_koff19 = 0.12; von27_kon27 = 75000; voff27_koff27 = 120; vcat27_kcat27 = 0.03; von15_kon15 = 3800000; vcat15_kcat15 = 10; voff15_koff15 = 24; von22_kon22 = 3800000; vcat22_kcat22 = 10; voff22_koff22 = 24; von25_kon25 = 3800000; vcat25_kcat25 = 10; voff25_koff25 = 24; von16_kon16 = 17000000; vcat16_kcat16 = 24; voff16_koff16 = 40; von23_kon23 = 17000000; vcat23_kcat23 = 24; voff23_koff23 = 40; vcat26_kcat26 = 24; von26_kon26 = 17000000; voff26_koff26 = 40; von20_kon20 = 7500000; vcat20_kcat20 = 3; voff20_koff20 = 12; von24_kon24 = 7500000; vcat24_kcat24 = 3; voff24_koff24 = 12; von28_kon28 = 7500000; vcat28_kcat28 = 3; voff28_koff28 = 12; von29_kon29 = 30000000; voff29_koff29 = 24; vcat29_kcat29 = 6; vcat30_kcat30 = 1; von31_kon31 = 6000000; vcat31_kcat31 = 9; voff31_koff31 = 36; vcat32_kcat32 = 0.1; von33_kon33 = 10000000; voff33_koff33 = 16; vcat33_kcat33 = 4; vcat34_kcat34 = 5; von35_kon35 = 1e+015; von36_kon36 = 3e+015; voff35_koff35 = 1; voff36_koff36 = 1; von37_kon37 = 54000000; von38_kon38 = 54000000; von39_kon39 = 75000000; von40_kon40 = 75000000; voff37_koff37 = 33; voff38_koff38 = 33; voff39_koff39 = 110; voff40_koff40 = 32.5; von41_kon41 = 18000000; voff41_koff41 = 60; von42_kon42 = 18000000; von43_kon43 = 60; von44_kon44 = 2520000; voff44_koff44 = 40; vcat44_kcat44 = 10; von45_kon45 = 5040000; voff45_koff45 = 80; vcat45_kcat45 = 20; v58_k58 = 1.7; // Other declarations: var k57; const Spine, cAMP_delay, cAMP_Ca_delay, kon_high, spike_duration, spike_interval; const kon_low; // Display Names: D34_75 is "D34:75"; D34_137 is "D34:137"; D75CK1 is "D75_CK1"; D75_137 is "D75:137"; D34_75_CK1 is "D34:75_CK1"; D34_137_CDK5 is "D34:137_CDK5"; D34_75_137 is "D34:75:137"; D75_137_PKA is "D75:137_PKA"; D34_75_PP2B is "D34:75_PP2B"; D34_137_PP2B is "D34:137_PP2B"; D34_75_137_PP2B is "D34:75:137_PP2B"; D34_75_PP2A is "D34:75_PP2A"; D75_137_PP2A is "D75:137_PP2A"; D34_75_134_PP2A is "D34:75:137_PP2A"; D34_75_PP2AP is "D34:75_PP2AP"; D75_137_PP2AP is "D75:137_PP2AP"; D34_75_137_PP2AP is "D34:75:137_PP2AP"; D34_137_PP2C is "D34:137_PP2C"; D75_137_PP2C is "D75:137_PP2C"; D34_75_137_PP2C is "D34:75:137_PP2C"; k57 is "ca_in"; ca_off1 is "ca_off"; von1 is "D_CDK5_binding"; voff1 is "D_CDK5_unbinding"; vcat1 is "DPhospho_by_CDK5_on_75"; von2 is "DCDK1_binding"; voff2 is "D_CDK1_unbinding"; vcat2 is "D_Phospho_by_CK1_on_137"; von3 is "D_PKA_binding"; voff3 is "D_PKA_unbinding"; vcat3 is "D_Phospho_by_PKA_on_34"; von4 is "D34_CDK5_binding"; von5 is "D34_CK1_binding"; von6 is "D34_PP2B_binding"; voff4 is "D34_CDK5_unbinding"; vcat4 is "D34_Phospho_by_CDK5_on_75"; voff5 is "D34_CK1_unbinding"; vcat5 is "D34_Phospho_by_CK1_on_137"; vcat6 is "D34_Dephospho_by_PP2B"; voff6 is "D34_PP2B_unbinding"; von7 is "D75_CK1_binding"; von8 is "D75_PKA_binding"; von9 is "D75_PP2A_binding"; von10 is "D75_PP2AP_binding"; voff7 is "D75_CK1_unbinding"; vcat7 is "D75_Phospho_by_CK1_on_137"; vcat8 is "D75_Phospho_by_PKA_on_34"; voff8 is "D75_PKA_unbinding"; vcat9 is "D75_dephospho_by_PP2A"; voff9 is "D75_PP2A_unbinding"; vcat10 is "D75_dephospho_by_PP2AP"; voff10 is "D75_PP2AP_unbinding"; von11 is "D137_CDK5_binding"; von12 is "D137_PKA_binding"; von13 is "D137_PP2C_binding"; voff11 is "D137_CDK5_unbinding"; vcat11 is "D137_Phospho_by_CDK5_on_75"; voff12 is "D137_PKA_unbinding"; vcat12 is "D137_phospho_by_PKA_on_34"; vcat13 is "D137_dephospho_by_PP2C"; voff13 is "D137_PP2C_unbinding"; von14 is "D34:75_CK1_binding"; von18 is "D34:137_CDK5_binding"; voff18 is "D34:137_CDK5_unbinding"; voff14 is "D34:75_CK1_unbinding"; vcat14 is "D34:75_phospho_by_CK1_on_137"; vcat18 is "D34:137_phospho_by_CDK5_on_75"; von21 is "D75:137_PKA_binding"; vcat21 is "D75:137_phospho_by_PKA_on_34"; voff21 is "D75:137_PKA_unbinding"; von17 is "D34:75_PP2B_binding"; voff17 is "D34:75_PP2B_unbinding"; vcat17 is "D34:75_dephopsho_by_PP2B_on_34"; von19 is "D34:137_PP2B_binding"; vcat19 is "D34:137_dephospho_by_PP2B_on_34"; voff19 is "D34:137_PP2B_unbinding"; von27 is "D34:75:137_PP2B_binding"; voff27 is "D34:75:137_PP2B_unbinding"; vcat27 is "D34:75:137_dephospho_by_PP2B_on_34"; von15 is "D34:75_PP2A_binding"; vcat15 is "D34:75_dephospho_by_PP2A_on_75"; voff15 is "D34:75_PP2A_unbinding"; von22 is "D75:137_PP2A_binding"; vcat22 is "D75:137_dephospho_by_PP2A_on_75"; voff22 is "D75:137_PP2A_unbinding"; von25 is "D34:75:137_PP2A_binding"; vcat25 is "D34:75:137_dephospho_by_PP2A_on_75"; voff25 is "D34:75:137_PP2A_unbinding"; von16 is "D34:75_PP2AP_binding"; vcat16 is "D34:75_dephospho_by_PP2AP_on_75"; voff16 is "D34:75_PP2AP_unbinding"; von23 is "D75:137_PP2AP_binding"; vcat23 is "D75:137_dephospho_by_PP2AP_on_75"; voff23 is "D75:137_PP2AP_unbinding"; vcat26 is "D34:75:137_dephospho_by_PP2AP_on 75"; von26 is "D34:75:137_PP2AP_binding"; voff26 is "D34:75:137_PP2AP_unbinding"; von20 is "D34:137_PP2C_binding"; vcat20 is "D34:137_dephospho_by_PP2C_on_137"; voff20 is "D34:137_PP2C_unbinding"; von24 is "D75:137_PP2C_binding"; vcat24 is "D75:137_dephospho_by_PP2C_137"; voff24 is "D75:137_PP2C_unbinding"; von28 is "D34:75:137_PP2C_binding"; vcat28 is "D34:75:137_dephospho_by_PP2C_on_137"; voff28 is "D34:75:137_PP2C_unbinding"; von29 is "CK1P_PP2B_binding"; voff29 is "CK1P_PP2B_unbinding"; vcat29 is "CK1P_dephospho_by_PP2B"; vcat30 is "CK1_phosphorylation"; von31 is "PDE_PKA_binding"; vcat31 is "PDE_phospho_by_PKA"; voff31 is "PDE_PKA_unbinding"; vcat32 is "PDEP_dephospho"; von33 is "PP2A_PKA_binding"; voff33 is "PP2A_PKA_unbinding"; vcat33 is "PP2A_phospho_by_PKA"; vcat34 is "PP2AP_dephospho"; von35 is "PP2Binactive_Ca_binding"; von36 is "PP2B_activation"; voff35 is "PP2BinactiveCa2_Ca_unbinding"; voff36 is "PP2B_inactivation"; von37 is "R2C2_cAMP_binding"; von38 is "cAMP_R2C2_binding_by_cAMP"; von39 is "cAMP2_R2C2_binding_by_cAMP"; von40 is "cAMP3_R2C2_binding_by_cAMP"; voff37 is "cAMP_R2C2_unbinding"; voff38 is "cAMP2_R2C2_unbinding"; voff39 is "cAMP3_R2C2_unbinding"; voff40 is "cAMP4_R2C2_unbinding"; von41 is "cAMP4_R2C_PKA_binding"; voff41 is "cAMP4_R2C2_PKA_unbinding"; von42 is "cAMP4_R2_PKA_binding"; von43 is "cAMP4_R2C_PKA_unbinding"; von44 is "cAMP_PDE_binding"; voff44 is "cAMP_PDE_unbinding"; vcat44 is "cAMP_PDE_degradation"; von45 is "cAMP_PDEP_binding"; voff45 is "cAMP_PDEP_unbinding"; vcat45 is "cAMP_PDEP_degradation"; v57 is "Ca_in"; v58 is "Ca_destroy"; end