// Created by libAntimony v2.8.0
model *Haberichter2007_cellcycle()

  // Compartments and Species:
  compartment X;
  species APCC in X, APCCYCdk1Y00YCdk1Y01YInt in X, APCCYCdk1Y10YCdk1Y11YInt in X;
  species APCCYCdk2Y000YCdk2Y002YInt in X, APCCYCdk2Y010YCdk2Y012YInt in X;
  species APCCYCdk2Y100YCdk2Y102YInt in X, APCCYCdk2Y110YCdk2Y112YInt in X;
  species APCCYCyclinAYInt in X, APCCYEmi1 in X, Cdk1Y00 in X, Cdk1Y01 in X;
  species Cdk1Y10 in X, Cdk1Y11 in X, Cdk1Y11YpRbY10YpRbY20YInt in X, Cdk1Y11YpRbY11YpRbY21YInt in X;
  species Cdk2Y000 in X, Cdk2Y001 in X, Cdk2Y002 in X, Cdk2Y010 in X, Cdk2Y011 in X;
  species Cdk2Y011YpRbY10YpRbY20YInt in X, Cdk2Y011YpRbY11YpRbY21YInt in X;
  species Cdk2Y012 in X, Cdk2Y012YpRbY10YpRbY20YInt in X, Cdk2Y012YpRbY11YpRbY21YInt in X;
  species Cdk2Y100 in X, Cdk2Y101 in X, Cdk2Y102 in X, Cdk2Y110 in X, Cdk2Y111 in X;
  species Cdk2Y112 in X, Cdk4Y00 in X, Cdk4Y01 in X, Cdk4Y01YpRbY00YpRbY10YInt in X;
  species Cdk4Y01YpRbY01YpRbY11YInt in X, Cdk4Y10 in X, Cdk4Y11 in X, CyclinA in X;
  species CyclinD in X, CyclinE in X, E2F in X, Emi1 in X, p27 in X, pRbY00 in X;
  species pRbY01 in X, pRbY10 in X, pRbY11 in X, pRbY20 in X, pRbY21 in X;
  species $totalYCyclinYD in X, $totalYCyclinYE in X, $totalYCyclinYA in X;
  species $totalYp27 in X, $hypophosphorylatedYpRb in X, $hyperphosphorylatedYpRb in X;
  species $totalYEmi1 in X, $activeYCdk2 in X;

  // Assignment Rules:
  totalYCyclinYD := CyclinD + Cdk4Y01 + Cdk4Y11;
  totalYCyclinYE := CyclinE + Cdk2Y001 + Cdk2Y011 + Cdk2Y101 + Cdk2Y111;
  totalYCyclinYA := CyclinA + Cdk1Y01 + Cdk1Y11 + Cdk2Y002 + Cdk2Y012 + Cdk2Y102 + Cdk2Y112;
  totalYp27 := p27 + Cdk4Y10 + Cdk4Y11 + Cdk2Y100 + Cdk2Y101 + Cdk2Y102 + Cdk2Y110 + Cdk2Y111 + Cdk2Y112;
  hypophosphorylatedYpRb := pRbY10 + pRbY11;
  hyperphosphorylatedYpRb := pRbY20 + pRbY21;
  totalYEmi1 := Emi1 + APCCYEmi1;
  activeYCdk2 := Cdk2Y011 + Cdk2Y012;
  ksYE2F := ks0YE2F + (ks1YE2F*E2F)/(ksMYE2F + E2F);
  ksYEmi1 := ks0YEmi1 + (ks1YEmi1*E2F)/(ksMYEmi1 + E2F);
  ksYCyclinA := ks0YCyclinA + (ks1YCyclinA*E2F)/(ksMYCyclinA + E2F);
  ksYCyclinE := ks0YCyclinE + (ks1YCyclinE*E2F)/(ksMYCyclinE + E2F);

  // Reactions:
  rxnY001:  => CyclinD; ksYCyclinD*X;
  rxnY002: CyclinD => ; kdYCyclinD*CyclinD*X;
  rxnY003: Cdk4Y01 => Cdk4Y00; kdYCyclinD*Cdk4Y01*X;
  rxnY004: Cdk4Y11 => Cdk4Y10; kdYCyclinD*Cdk4Y11*X;
  rxnY005:  => p27; ksYp27*X;
  rxnY006: p27 => ; kdYp27*p27*X;
  rxnY007: Cdk4Y10 => Cdk4Y00; kdYp27*Cdk4Y10*X;
  rxnY008: Cdk4Y11 => Cdk4Y01; kdYp27*Cdk4Y11*X;
  rxnY009: Cdk2Y100 => Cdk2Y000; kdYp27*Cdk2Y100*X;
  rxnY010: Cdk2Y101 => Cdk2Y001; kdYp27*Cdk2Y101*X;
  rxnY011: Cdk2Y102 => Cdk2Y002; kdYp27*Cdk2Y102*X;
  rxnY012: Cdk2Y110 => Cdk2Y010; kdYp27*Cdk2Y110*X;
  rxnY013: Cdk2Y111 => Cdk2Y011; kd1Yp27*Cdk2Y111*X;
  rxnY014: Cdk2Y112 => Cdk2Y012; kdYp27*Cdk2Y112*X;
  rxnY015:  => CyclinE; ksYCyclinE*X;
  rxnY016: CyclinE => ; kdYCyclinE*CyclinE*X;
  rxnY017: Cdk2Y001 => Cdk2Y000; kdYCyclinE*Cdk2Y001*X;
  rxnY018: Cdk2Y101 => Cdk2Y100; kdYCyclinE*Cdk2Y101*X;
  rxnY019: Cdk2Y011 => Cdk2Y010; kdYCyclinE*Cdk2Y011*X;
  rxnY020: Cdk2Y111 => Cdk2Y110; kdYCyclinE*Cdk2Y111*X;
  rxnY021:  => CyclinA; ksYCyclinA*X;
  rxnY022: CyclinA => ; kdYCyclinA*CyclinA*X;
  rxnY023: Cdk1Y01 => Cdk1Y00; kdYCyclinA*Cdk1Y01*X;
  rxnY024: Cdk1Y11 => Cdk1Y10; kdYCyclinA*Cdk1Y11*X;
  rxnY025: Cdk2Y002 => Cdk2Y000; kdYCyclinA*Cdk2Y002*X;
  rxnY026: Cdk2Y102 => Cdk2Y100; kdYCyclinA*Cdk2Y102*X;
  rxnY027: Cdk2Y012 => Cdk2Y010; kdYCyclinA*Cdk2Y012*X;
  rxnY028: Cdk2Y112 => Cdk2Y110; kdYCyclinA*Cdk2Y112*X;
  rxnY029:  => E2F; ksYE2F*X;
  rxnY030: E2F => ; kd0YE2F*E2F*X;
  rxnY031: pRbY01 => pRbY00; kdYE2F*pRbY01*X;
  rxnY032: pRbY11 => pRbY10; kdYE2F*pRbY11*X;
  rxnY033: pRbY21 => pRbY20; kdYE2F*pRbY21*X;
  rxnY034:  => Emi1; ksYEmi1*X;
  rxnY035: Emi1 => ; kdYEmi1*Emi1*X;
  rxnY036: APCCYEmi1 => APCC; kdYEmi1*APCCYEmi1*X;
  rxnY037: Cdk4Y00 + CyclinD => Cdk4Y01; kbYCyclinDYYCdk4*Cdk4Y00*CyclinD*X;
  rxnY038: Cdk4Y01 => Cdk4Y00 + CyclinD; kuYCyclinDYYCdk4*Cdk4Y01*X;
  rxnY039: Cdk4Y10 + CyclinD => Cdk4Y11; kbYCyclinDYYCdk4*Cdk4Y10*CyclinD*X;
  rxnY040: Cdk4Y11 => Cdk4Y10 + CyclinD; kuYCyclinDYYCdk4*Cdk4Y11*X;
  rxnY041: Cdk4Y00 + p27 => Cdk4Y10; kbYp27YYCdk4*Cdk4Y00*p27*X;
  rxnY042: Cdk4Y10 => Cdk4Y00 + p27; kuYp27YYCdk4*Cdk4Y10*X;
  rxnY043: Cdk4Y01 + p27 => Cdk4Y11; kbYp27YYCdk4*Cdk4Y01*p27*X;
  rxnY044: Cdk4Y11 => Cdk4Y01 + p27; kuYp27YYCdk4*Cdk4Y11*X;
  rxnY045: Cdk2Y000 + p27 => Cdk2Y100; kbYp27YYCdk2*Cdk2Y000*p27*X;
  rxnY046: Cdk2Y100 => Cdk2Y000 + p27; kuYp27YYCdk2*Cdk2Y100*X;
  rxnY047: Cdk2Y001 + p27 => Cdk2Y101; kbYp27YYCdk2*Cdk2Y001*p27*X;
  rxnY048: Cdk2Y101 => Cdk2Y001 + p27; kuYp27YYCdk2*Cdk2Y101*X;
  rxnY049: Cdk2Y002 + p27 => Cdk2Y102; kbYp27YYCdk2*Cdk2Y002*p27*X;
  rxnY050: Cdk2Y102 => Cdk2Y002 + p27; kuYp27YYCdk2*Cdk2Y102*X;
  rxnY051: Cdk2Y010 + p27 => Cdk2Y110; kbYp27YYCdk2*Cdk2Y010*p27*X;
  rxnY052: Cdk2Y110 => Cdk2Y010 + p27; kuYp27YYCdk2*Cdk2Y110*X;
  rxnY053: Cdk2Y011 + p27 => Cdk2Y111; kbYp27YYCdk2*Cdk2Y011*p27*X;
  rxnY054: Cdk2Y111 => Cdk2Y011 + p27; kuYp27YYCdk2*Cdk2Y111*X;
  rxnY055: Cdk2Y012 + p27 => Cdk2Y112; kbYp27YYCdk2*Cdk2Y012*p27*X;
  rxnY056: Cdk2Y112 => Cdk2Y012 + p27; kuYp27YYCdk2*Cdk2Y112*X;
  rxnY057: Cdk2Y000 => Cdk2Y010; kYact*Cdk2Y000*X;
  rxnY058: Cdk2Y100 => Cdk2Y110; kYact*Cdk2Y100*X;
  rxnY059: Cdk2Y001 => Cdk2Y011; kYact*Cdk2Y001*X;
  rxnY060: Cdk2Y101 => Cdk2Y111; kYact*Cdk2Y101*X;
  rxnY061: Cdk2Y002 => Cdk2Y012; kYact*Cdk2Y002*X;
  rxnY062: Cdk2Y102 => Cdk2Y112; kYact*Cdk2Y102*X;
  rxnY063: Cdk2Y000 + CyclinE => Cdk2Y001; kbYCyclinEYYCdk2*Cdk2Y000*CyclinE*X;
  rxnY064: Cdk2Y001 => Cdk2Y000 + CyclinE; kuYCyclinEYYCdk2*Cdk2Y001*X;
  rxnY065: Cdk2Y100 + CyclinE => Cdk2Y101; kbYCyclinEYYCdk2*Cdk2Y100*CyclinE*X;
  rxnY066: Cdk2Y101 => Cdk2Y100 + CyclinE; kuYCyclinEYYCdk2*Cdk2Y101*X;
  rxnY067: Cdk2Y010 + CyclinE => Cdk2Y011; kbYCyclinEYYCdk2*Cdk2Y010*CyclinE*X;
  rxnY068: Cdk2Y011 => Cdk2Y010 + CyclinE; kuYCyclinEYYCdk2*Cdk2Y011*X;
  rxnY069: Cdk2Y110 + CyclinE => Cdk2Y111; kbYCyclinEYYCdk2*Cdk2Y110*CyclinE*X;
  rxnY070: Cdk2Y111 => Cdk2Y110 + CyclinE; kuYCyclinEYYCdk2*Cdk2Y111*X;
  rxnY071: Cdk2Y000 + CyclinA => Cdk2Y002; kbYCyclinAYYCdk2*Cdk2Y000*CyclinA*X;
  rxnY072: Cdk2Y002 => Cdk2Y000 + CyclinA; kuYCyclinAYYCdk2*Cdk2Y002*X;
  rxnY073: Cdk2Y100 + CyclinA => Cdk2Y102; kbYCyclinAYYCdk2*Cdk2Y100*CyclinA*X;
  rxnY074: Cdk2Y102 => Cdk2Y100 + CyclinA; X*kuYCyclinAYYCdk2*Cdk2Y102;
  rxnY075: Cdk2Y010 + CyclinA => Cdk2Y012; X*kbYCyclinAYYCdk2*Cdk2Y010*CyclinA;
  rxnY076: Cdk2Y012 => Cdk2Y010 + CyclinA; X*kuYCyclinAYYCdk2*Cdk2Y012;
  rxnY077: Cdk2Y110 + CyclinA => Cdk2Y112; X*kbYCyclinAYYCdk2*Cdk2Y110*CyclinA;
  rxnY078: Cdk2Y112 => Cdk2Y110 + CyclinA; X*kuYCyclinAYYCdk2*Cdk2Y112;
  rxnY079: Cdk1Y00 => Cdk1Y10; X*kYact*Cdk1Y00;
  rxnY080: Cdk1Y01 => Cdk1Y11; X*kYact*Cdk1Y01;
  rxnY081: Cdk1Y00 + CyclinA => Cdk1Y01; X*kbYCyclinAYYCdk1*Cdk1Y00*CyclinA;
  rxnY082: Cdk1Y01 => Cdk1Y00 + CyclinA; X*kuYCyclinAYYCdk1*Cdk1Y01;
  rxnY083: Cdk1Y10 + CyclinA => Cdk1Y11; X*kbYCyclinAYYCdk1*Cdk1Y10*CyclinA;
  rxnY084: Cdk1Y11 => Cdk1Y10 + CyclinA; X*kuYCyclinAYYCdk1*Cdk1Y11;
  rxnY085: pRbY00 + Cdk4Y01 => Cdk4Y01YpRbY00YpRbY10YInt; X*kbYD4YYpRb*pRbY00*Cdk4Y01;
  rxnY086: Cdk4Y01YpRbY00YpRbY10YInt => pRbY00 + Cdk4Y01; X*kuYD4YYpRb*Cdk4Y01YpRbY00YpRbY10YInt;
  rxnY087: Cdk4Y01YpRbY00YpRbY10YInt => pRbY10 + Cdk4Y01; X*kupYD4YYpRb*Cdk4Y01YpRbY00YpRbY10YInt;
  rxnY088: pRbY01 + Cdk4Y01 => Cdk4Y01YpRbY01YpRbY11YInt; X*kbYD4YYpRb*pRbY01*Cdk4Y01;
  rxnY089: Cdk4Y01YpRbY01YpRbY11YInt => pRbY01 + Cdk4Y01; X*kuYD4YYpRb*Cdk4Y01YpRbY01YpRbY11YInt;
  rxnY090: Cdk4Y01YpRbY01YpRbY11YInt => pRbY11 + Cdk4Y01; X*kupYD4YYpRb*Cdk4Y01YpRbY01YpRbY11YInt;
  rxnY091: pRbY10 + Cdk2Y011 => Cdk2Y011YpRbY10YpRbY20YInt; X*kbYE2YYpRb*pRbY10*Cdk2Y011;
  rxnY092: Cdk2Y011YpRbY10YpRbY20YInt => pRbY10 + Cdk2Y011; X*kuYE2YYpRb*Cdk2Y011YpRbY10YpRbY20YInt;
  rxnY093: Cdk2Y011YpRbY10YpRbY20YInt => pRbY20 + Cdk2Y011; X*kupYE2YYpRb*Cdk2Y011YpRbY10YpRbY20YInt;
  rxnY094: pRbY11 + Cdk2Y011 => Cdk2Y011YpRbY11YpRbY21YInt; X*kbYE2YYpRb*pRbY11*Cdk2Y011;
  rxnY095: Cdk2Y011YpRbY11YpRbY21YInt => pRbY11 + Cdk2Y011; X*kuYE2YYpRb*Cdk2Y011YpRbY11YpRbY21YInt;
  rxnY096: Cdk2Y011YpRbY11YpRbY21YInt => pRbY21 + Cdk2Y011; X*kupYE2YYpRb*Cdk2Y011YpRbY11YpRbY21YInt;
  rxnY097: pRbY10 + Cdk2Y012 => Cdk2Y012YpRbY10YpRbY20YInt; X*kbYA2YYpRb*pRbY10*Cdk2Y012;
  rxnY098: Cdk2Y012YpRbY10YpRbY20YInt => pRbY10 + Cdk2Y012; X*kuYA2YYpRb*Cdk2Y012YpRbY10YpRbY20YInt;
  rxnY099: Cdk2Y012YpRbY10YpRbY20YInt => pRbY20 + Cdk2Y012; X*kupYA2YYpRb*Cdk2Y012YpRbY10YpRbY20YInt;
  rxnY100: pRbY11 + Cdk2Y012 => Cdk2Y012YpRbY11YpRbY21YInt; X*kbYA2YYpRb*pRbY11*Cdk2Y012;
  rxnY101: Cdk2Y012YpRbY11YpRbY21YInt => pRbY11 + Cdk2Y012; X*kuYA2YYpRb*Cdk2Y012YpRbY11YpRbY21YInt;
  rxnY102: Cdk2Y012YpRbY11YpRbY21YInt => pRbY21 + Cdk2Y012; X*kupYA2YYpRb*Cdk2Y012YpRbY11YpRbY21YInt;
  rxnY103: pRbY10 + Cdk1Y11 => Cdk1Y11YpRbY10YpRbY20YInt; X*kbYA1YYpRb*pRbY10*Cdk1Y11;
  rxnY104: Cdk1Y11YpRbY10YpRbY20YInt => pRbY10 + Cdk1Y11; X*kuYA1YYpRb*Cdk1Y11YpRbY10YpRbY20YInt;
  rxnY105: Cdk1Y11YpRbY10YpRbY20YInt => pRbY20 + Cdk1Y11; X*kupYA1YYpRb*Cdk1Y11YpRbY10YpRbY20YInt;
  rxnY106: pRbY11 + Cdk1Y11 => Cdk1Y11YpRbY11YpRbY21YInt; X*kbYA1YYpRb*pRbY10*Cdk1Y11;
  rxnY107: Cdk1Y11YpRbY11YpRbY21YInt => pRbY11 + Cdk1Y11; X*kuYA1YYpRb*Cdk1Y11YpRbY11YpRbY21YInt;
  rxnY108: Cdk1Y11YpRbY11YpRbY21YInt => pRbY21 + Cdk1Y11; X*kupYA1YYpRb*Cdk1Y11YpRbY11YpRbY21YInt;
  rxnY109: pRbY20 => pRbY00; X*ktYpRbYYDephos*pRbY20;
  rxnY110: pRbY21 => pRbY01; X*ktYpRbYYDephos*pRbY21;
  rxnY111: pRbY00 + E2F => pRbY01; X*kbYE2FYYpRb*pRbY00*E2F;
  rxnY112: pRbY01 => pRbY00 + E2F; X*kuYE2FYYpRb*pRbY01;
  rxnY113: pRbY10 + E2F => pRbY11; X*kbYE2FYYpRb*pRbY10*E2F;
  rxnY114: pRbY11 => pRbY10 + E2F; X*kuYE2FYYpRb*pRbY11;
  rxnY115: pRbY21 => pRbY20 + E2F; X*kuYE2FYYpRb*pRbY21;
  rxnY116: APCC + Emi1 => APCCYEmi1; X*kbYEmi1YYAPCC*APCC*Emi1;
  rxnY117: APCCYEmi1 => APCC + Emi1; X*kuYEmi1YYAPCC*APCCYEmi1;
  rxnY118: CyclinA + APCC => APCCYCyclinAYInt; X*kbYAPCCYYCyclinA*CyclinA*APCC;
  rxnY119: APCCYCyclinAYInt => CyclinA + APCC; X*kuYAPCCYYCyclinA*APCCYCyclinAYInt;
  rxnY120: APCCYCyclinAYInt => APCC; X*kudYAPCCYYCyclinA*APCCYCyclinAYInt;
  rxnY121: Cdk2Y002 + APCC => APCCYCdk2Y000YCdk2Y002YInt; X*kbYAPCCYYCyclinA*Cdk2Y002*APCC;
  rxnY122: APCCYCdk2Y000YCdk2Y002YInt => Cdk2Y002 + APCC; X*kuYAPCCYYCyclinA*APCCYCdk2Y000YCdk2Y002YInt;
  rxnY123: APCCYCdk2Y000YCdk2Y002YInt => Cdk2Y000 + APCC; X*kudYAPCCYYCyclinA*APCCYCdk2Y000YCdk2Y002YInt;
  rxnY124: Cdk2Y102 + APCC => APCCYCdk2Y100YCdk2Y102YInt; X*kbYAPCCYYCyclinA*Cdk2Y102*APCC;
  rxnY125: APCCYCdk2Y100YCdk2Y102YInt => Cdk2Y102 + APCC; X*kuYAPCCYYCyclinA*APCCYCdk2Y100YCdk2Y102YInt;
  rxnY126: APCCYCdk2Y100YCdk2Y102YInt => Cdk2Y100 + APCC; X*kudYAPCCYYCyclinA*APCCYCdk2Y100YCdk2Y102YInt;
  rxnY127: Cdk2Y012 + APCC => APCCYCdk2Y010YCdk2Y012YInt; X*kbYAPCCYYCyclinA*Cdk2Y102*APCC;
  rxnY128: APCCYCdk2Y010YCdk2Y012YInt => Cdk2Y012 + APCC; X*kuYAPCCYYCyclinA*APCCYCdk2Y010YCdk2Y012YInt;
  rxnY129: APCCYCdk2Y010YCdk2Y012YInt => Cdk2Y010 + APCC; X*kudYAPCCYYCyclinA*APCCYCdk2Y010YCdk2Y012YInt;
  rxnY130: Cdk2Y112 + APCC => APCCYCdk2Y110YCdk2Y112YInt; X*kbYAPCCYYCyclinA*Cdk2Y112*APCC;
  rxnY131: APCCYCdk2Y110YCdk2Y112YInt => Cdk2Y112 + APCC; X*kuYAPCCYYCyclinA*APCCYCdk2Y110YCdk2Y112YInt;
  rxnY132: APCCYCdk2Y110YCdk2Y112YInt => Cdk2Y110 + APCC; X*kudYAPCCYYCyclinA*APCCYCdk2Y110YCdk2Y112YInt;
  rxnY133: Cdk1Y01 + APCC => APCCYCdk1Y00YCdk1Y01YInt; X*kbYAPCCYYCyclinA*Cdk1Y01*APCC;
  rxnY134: APCCYCdk1Y00YCdk1Y01YInt + APCC => Cdk1Y01; X*kuYAPCCYYCyclinA*APCCYCdk1Y00YCdk1Y01YInt;
  rxnY135: APCCYCdk1Y00YCdk1Y01YInt => Cdk1Y00 + APCC; X*kudYAPCCYYCyclinA*APCCYCdk1Y00YCdk1Y01YInt;
  rxnY136: Cdk1Y11 + APCC => APCCYCdk1Y10YCdk1Y11YInt; X*kbYAPCCYYCyclinA*Cdk1Y11*APCC;
  rxnY137: APCCYCdk1Y10YCdk1Y11YInt + APCC => Cdk1Y11; X*kuYAPCCYYCyclinA*APCCYCdk1Y10YCdk1Y11YInt;
  rxnY138: APCCYCdk1Y10YCdk1Y11YInt => Cdk1Y10 + APCC; X*kudYAPCCYYCyclinA*APCCYCdk1Y10YCdk1Y11YInt;

  // Events:
  modifier_activation: at time > 240.0637: kYact = k1Yact;

  // Species initializations:
  APCC = 24582.9/X;
  APCCYCdk1Y00YCdk1Y01YInt = 104.388/X;
  APCCYCdk1Y10YCdk1Y11YInt = 0;
  APCCYCdk2Y000YCdk2Y002YInt = 52.8191/X;
  APCCYCdk2Y010YCdk2Y012YInt = 0;
  APCCYCdk2Y100YCdk2Y102YInt = 90.5091/X;
  APCCYCdk2Y110YCdk2Y112YInt = 0;
  APCCYCyclinAYInt = 8.79462/X;
  APCCYEmi1 = 5160.61/X;
  Cdk1Y00 = 98550.6/X;
  Cdk1Y01 = 1345.01/X;
  Cdk1Y10 = 0;
  Cdk1Y11 = 0;
  Cdk1Y11YpRbY10YpRbY20YInt = 0;
  Cdk1Y11YpRbY11YpRbY21YInt = 0;
  Cdk2Y000 = 33942/X;
  Cdk2Y001 = 2176.46/X;
  Cdk2Y002 = 680.557/X;
  Cdk2Y010 = 0;
  Cdk2Y011 = 0;
  Cdk2Y011YpRbY10YpRbY20YInt = 0;
  Cdk2Y011YpRbY11YpRbY21YInt = 0;
  Cdk2Y012 = 0;
  Cdk2Y012YpRbY10YpRbY20YInt = 0;
  Cdk2Y012YpRbY11YpRbY21YInt = 0;
  Cdk2Y100 = 58162/X;
  Cdk2Y101 = 3729.51/X;
  Cdk2Y102 = 1166.18/X;
  Cdk2Y110 = 0;
  Cdk2Y111 = 0;
  Cdk2Y112 = 0;
  Cdk4Y00 = 46551.9/X;
  Cdk4Y01 = 6547.64/X;
  Cdk4Y01YpRbY00YpRbY10YInt = 0;
  Cdk4Y01YpRbY01YpRbY11YInt = 0;
  Cdk4Y10 = 41117.2/X;
  Cdk4Y11 = 5783.23/X;
  CyclinA = 113.316/X;
  CyclinD = 14753.7/X;
  CyclinE = 191.985/X;
  E2F = 546.211/X;
  Emi1 = 248.046/X;
  p27 = 14150.9/X;
  pRbY00 = 30000/X;
  pRbY01 = 0;
  pRbY10 = 28583.4/X;
  pRbY11 = 1416.59/X;
  pRbY20 = 0;
  pRbY21 = 0;

  // Compartment initializations:
  X = 1;

  // Variable initializations:
  kYact = 0;
  k1Yact = 0.01075;
  ks0YE2F = 6.927086;
  ks1YE2F = 65.44282;
  ksMYE2F = 9818.78;
  ks0YEmi1 = 2.004744;
  ks1YEmi1 = 1788.517;
  ksMYEmi1 = 9608.162;
  ks0YCyclinA = 499.9437;
  ks1YCyclinA = 7999.996;
  ksMYCyclinA = 4064.384;
  ks0YCyclinE = 254.0742;
  ks1YCyclinE = 980.611;
  ksMYCyclinE = 9992.647;
  ksYCyclinD = 1354.231;
  ksYp27 = 195.4716;
  kdYp27 = 0.001575;
  kd1Yp27 = 0.071149;
  kdYE2F = 0.006465;
  kd0YE2F = 0.002229;
  kdYEmi1 = 0.018158;
  kbYCyclinDYYCdk4 = 1.43e-006;
  kbYp27YYCdk4 = 6.34e-006;
  kbYp27YYCdk2 = 1.23e-005;
  timeYModifier = 240.0637;
  kbYCyclinEYYCdk2 = 5.01e-005;
  kbYCyclinAYYCdk2 = 9.52e-005;
  kbYCyclinAYYCdk1 = 6.48e-005;
  kbYD4YYpRb = 3.15e-005;
  kupYD4YYpRb = 1.694662;
  kbYE2YYpRb = 5.74e-005;
  kupYE2YYpRb = 4.78271;
  kbYA2YYpRb = 6.25e-005;
  kupYA2YYpRb = 0.200091;
  kbYA1YYpRb = 6.73e-005;
  kupYA1YYpRb = 0.202132;
  ktYpRbYYDephos = 0.023194;
  kbYE2FYYpRb = 9.66e-006;
  kbYEmi1YYAPCC = 0.0001;
  kbYAPCCYYCyclinA = 1.61e-005;
  kudYAPCCYYCyclinA = 4.999555;
  kdYCyclinD = 0.05;
  kdYCyclinE = 0.05;
  kdYCyclinA = 0.05;
  kuYCyclinDYYCdk4 = 0.1;
  kuYp27YYCdk4 = 0.1;
  kuYCyclinEYYCdk2 = 0.1;
  kuYp27YYCdk2 = 0.1;
  kuYCyclinAYYCdk2 = 0.1;
  kuYCyclinAYYCdk1 = 0.1;
  kuYD4YYpRb = 0.1;
  kuYE2YYpRb = 0.1;
  kuYA2YYpRb = 0.1;
  kuYA1YYpRb = 0.1;
  kuYE2FYYpRb = 0.1;
  kuYEmi1YYAPCC = 0.1;
  kuYAPCCYYCyclinA = 0.1;

  // Other declarations:
  var kYact, ksYE2F, ksYEmi1, ksYCyclinA, ksYCyclinE;
  const X, k1Yact, ks0YE2F, ks1YE2F, ksMYE2F, ks0YEmi1, ks1YEmi1, ksMYEmi1;
  const ks0YCyclinA, ks1YCyclinA, ksMYCyclinA, ks0YCyclinE, ks1YCyclinE, ksMYCyclinE;
  const ksYCyclinD, ksYp27, kdYp27, kd1Yp27, kdYE2F, kd0YE2F, kdYEmi1, kbYCyclinDYYCdk4;
  const kbYp27YYCdk4, kbYp27YYCdk2, timeYModifier, kbYCyclinEYYCdk2, kbYCyclinAYYCdk2;
  const kbYCyclinAYYCdk1, kbYD4YYpRb, kupYD4YYpRb, kbYE2YYpRb, kupYE2YYpRb;
  const kbYA2YYpRb, kupYA2YYpRb, kbYA1YYpRb, kupYA1YYpRb, ktYpRbYYDephos;
  const kbYE2FYYpRb, kbYEmi1YYAPCC, kbYAPCCYYCyclinA, kudYAPCCYYCyclinA, kdYCyclinD;
  const kdYCyclinE, kdYCyclinA, kuYCyclinDYYCdk4, kuYp27YYCdk4, kuYCyclinEYYCdk2;
  const kuYp27YYCdk2, kuYCyclinAYYCdk2, kuYCyclinAYYCdk1, kuYD4YYpRb, kuYE2YYpRb;
  const kuYA2YYpRb, kuYA1YYpRb, kuYE2FYYpRb, kuYEmi1YYAPCC, kuYAPCCYYCyclinA;

  // Unit definitions:
  unit time_unit = 60 second;
  unit substance = item;

  // Display Names:
  time_unit is "min";
  substance is "#";
  X is "cell";
  modifier_activation is "modifier activation";
end