$-(\mathrm{i\_Na}+\mathrm{i\_Nab}+\mathrm{i\_NaK}+\mathrm{i\_Kr}+\mathrm{i\_Ks}+\mathrm{i\_tos}+\mathrm{i\_tof}+\mathrm{i\_K1}+\mathrm{i\_Kp}+\mathrm{i\_NaCa}+\mathrm{i\_Cl\_Ca}+\mathrm{i\_Clb}+\mathrm{i\_CaL}+\mathrm{i\_Cab}+\mathrm{i\_Cap}+\mathrm{i\_Stim})$ $\begin{cases}-\mathrm{stim\_amplitude} & \text{if $(\mathrm{time\_}-\lfloor \frac{\mathrm{time\_}}{\mathrm{stim\_period}}\rfloor \mathrm{stim\_period}\ge \mathrm{stim\_start})\land (\mathrm{time\_}-\lfloor \frac{\mathrm{time\_}}{\mathrm{stim\_period}}\rfloor \mathrm{stim\_period}\le \mathrm{stim\_start}+\mathrm{stim\_duration})$}\\ 0 & \text{otherwise}\end{cases}$ $\frac{\frac{\mathrm{Cm\_per\_area}\times 2\mathrm{cell\_radius}}{10000}\pi \mathrm{cell\_length}}{10000}$ $\frac{3.141592654\left(\frac{\mathrm{cell\_radius}}{1000}\right)^2\mathrm{cell\_length}}{1000^3}$ $0.035\mathrm{Vol\_Cell}$ $0.02\mathrm{Vol\_Cell}$ $0.00051\mathrm{Vol\_Cell}$ $0.65\mathrm{Vol\_Cell}$ $\mathrm{Vol\_Cell}-\mathrm{Vol\_SR}+\mathrm{Vol\_SL}+\mathrm{Vol\_jct}+\mathrm{Vol\_cytosol}$ $\frac{RT}{F}\ln \left(\frac{\mathrm{Nao}}{\mathrm{Na\_jct}}\right)$ $\frac{RT}{F}\ln \left(\frac{\mathrm{Nao}}{\mathrm{Na\_SL}}\right)$ $\frac{RT}{2F}\ln \left(\frac{\mathrm{Cao}}{\mathrm{Ca\_jct}}\right)$ $\frac{RT}{2F}\ln \left(\frac{\mathrm{Cao}}{\mathrm{Ca\_SL}}\right)$ $\frac{RT}{F}\ln \left(\frac{\mathrm{Ko}}{\mathrm{Ki}}\right)$ $\frac{-RT}{F}\ln \left(\frac{\mathrm{Clo}}{\mathrm{Cli}}\right)$ $\frac{\mathrm{m\_infinity}-m}{\mathrm{tau\_m}}$ $\frac{\frac{0.32(V+47.13)}{1}}{1-e^{-0.1(V+47.13)}}$ $0.08e^{\frac{-V}{11}}$ $\frac{1}{\mathrm{alpha\_m}+\mathrm{beta\_m}}$ $\frac{\mathrm{alpha\_m}}{\mathrm{alpha\_m}+\mathrm{beta\_m}}$ $\frac{\mathrm{h\_infinity}-h}{\mathrm{tau\_h}}$ $\begin{cases}0.135e^{\frac{80+V}{-6.8}} & \text{if $V< -40$}\\ 0 & \text{otherwise}\end{cases}$ $\begin{cases}3.56e^{0.079V}+3.1E5e^{0.35V} & \text{if $V< -40$}\\ \frac{1}{0.13(1+e^{\frac{V+10.66}{-11.1}})} & \text{otherwise}\end{cases}$ $\frac{1}{\mathrm{alpha\_h}+\mathrm{beta\_h}}$ $\frac{\mathrm{alpha\_h}}{\mathrm{alpha\_h}+\mathrm{beta\_h}}$ $\frac{\mathrm{j\_infinity}-j}{\mathrm{tau\_j}}$ $\begin{cases}\frac{\frac{(-1.2714E5e^{0.2444V}-3.474E-5e^{-0.04391V})(V+37.78)}{1}}{1+e^{0.311(V+79.23)}} & \text{if $V< -40$}\\ 0 & \text{otherwise}\end{cases}$ $\begin{cases}\frac{0.1212e^{-0.01052V}}{1+e^{-0.1378(V+40.14)}} & \text{if $V< -40$}\\ \frac{0.3e^{-2.535E-7V}}{1+e^{-0.1(V+32)}} & \text{otherwise}\end{cases}$ $\frac{1}{\mathrm{alpha\_j}+\mathrm{beta\_j}}$ $\frac{\mathrm{alpha\_j}}{\mathrm{alpha\_j}+\mathrm{beta\_j}}$ $\mathrm{i\_Na\_jct}+\mathrm{i\_Na\_SL}$ $\mathrm{Fx\_Na\_jct}\mathrm{G\_INa}\mathrm{openProb}(V-\mathrm{E\_Na\_jct})$ $\mathrm{Fx\_Na\_SL}\mathrm{G\_INa}\mathrm{openProb}(V-\mathrm{E\_Na\_SL})$ $m^{3}hj$ $\mathrm{i\_Nab\_jct}+\mathrm{i\_Nab\_SL}$ $\mathrm{Fx\_NaBk\_jct}\mathrm{G\_NaBk}(V-\mathrm{E\_Na\_jct})$ $\mathrm{Fx\_NaBk\_SL}\mathrm{G\_NaBk}(V-\mathrm{E\_Na\_SL})$ $\mathrm{i\_NaK\_jct}+\mathrm{i\_NaK\_SL}$ $\frac{\frac{\mathrm{Fx\_NaK\_jct}\mathrm{Q\_NaK}\mathrm{I\_NaK\_max}\mathrm{f\_NaK}}{1+\left(\frac{\mathrm{Q\_Km\_Nai}\mathrm{Km\_Nai}}{\mathrm{Na\_jct}}\right)^{\mathrm{H\_NaK}}}\mathrm{Ko}}{\mathrm{Ko}+\mathrm{Km\_Ko}}$ $\frac{\frac{\mathrm{Fx\_NaK\_SL}\mathrm{Q\_NaK}\mathrm{I\_NaK\_max}\mathrm{f\_NaK}}{1+\left(\frac{\mathrm{Q\_Km\_Nai}\mathrm{Km\_Nai}}{\mathrm{Na\_SL}}\right)^{\mathrm{H\_NaK}}}\mathrm{Ko}}{\mathrm{Ko}+\mathrm{Km\_Ko}}$ $\frac{1}{1+0.1245e^{\frac{-0.1VF}{RT}}+0.0365\mathrm{sigma}e^{\frac{-VF}{RT}}}$ $\mathrm{Q10\_NaK}^{\left(\frac{T-310}{10}\right)}$ $\mathrm{Q10\_Km\_Nai}^{\left(\frac{T-310}{10}\right)}$ $\frac{e^{\frac{\mathrm{Nao}}{67.3}}-1}{7}$ $\frac{\mathrm{Xr\_infinity}-\mathrm{Xr}}{\mathrm{tau\_Xr}}$ $\frac{1}{1+e^{\frac{-(50+V)}{7.5}}}$ $\frac{1}{\frac{0.00138(V+7)}{1-e^{-0.123(V+7)}}+\frac{0.00061(V+10)}{e^{0.145(V+10)}-1}}$ $\frac{1}{1+e^{\frac{33+V}{22.4}}}$ $\mathrm{G\_IKr}\mathrm{Xr}\mathrm{Rr}(V-\mathrm{E\_K})$ $0.03\sqrt{\frac{\mathrm{Ko}}{5.4}}$ $\frac{\mathrm{Xs\_infinity}-\mathrm{Xs}}{\mathrm{tau\_Xs}}$ $\frac{1}{1+e^{\frac{-(V-1.5)}{16.7}}}$ $\frac{1}{\frac{7.19E-5(V+30)}{1-e^{-0.148(V+30)}}+\frac{1.31E-4(V+30)}{-1+e^{0.0687(V+30)}}}$ $\mathrm{i\_Ks\_jct}+\mathrm{i\_Ks\_SL}$ $\mathrm{Fx\_Ks\_jct}\mathrm{G\_Ks\_jct}\mathrm{Xs}^2(V-\mathrm{E\_Ks})$ $\mathrm{Fx\_Ks\_SL}\mathrm{G\_Ks\_SL}\mathrm{Xs}^2(V-\mathrm{E\_Ks})$ $0.07(0.057+\frac{0.19}{1+e^{-7.2+\frac{\mathrm{pCa\_SL}}{0.6}}})$ $0.07(0.057+\frac{0.19}{1+e^{-7.2+\frac{\mathrm{pCa\_jct}}{0.6}}})$ $\frac{RT}{F}\ln \left(\frac{\mathrm{Ko}+\mathrm{pKNa}\mathrm{Nao}}{\mathrm{Ki}+\mathrm{pKNa}\mathrm{Na\_jct}}\right)$ $\frac{RT}{F}\ln \left(\frac{\mathrm{Ko}+\mathrm{pKNa}\mathrm{Nao}}{\mathrm{Ki}+\mathrm{pKNa}\mathrm{Na\_SL}}\right)$ $\frac{RT}{F}\ln \left(\frac{\mathrm{Ko}+\mathrm{pKNa}\mathrm{Nao}}{\mathrm{Ki}+\mathrm{pKNa}\mathrm{Nai}}\right)$ $-\ln (\frac{\mathrm{Ca\_jct}}{1}+3)$ $-\ln (\frac{\mathrm{Ca\_SL}}{1}+3)$ $\frac{\mathrm{X\_tos\_infinity}-\mathrm{X\_tos}}{\mathrm{tau\_X\_tos}}$ $\frac{1}{1+e^{\frac{-(V+3)}{15}}}$ $\frac{9}{1+e^{\frac{V+3}{15}}}+0.5$ $\frac{\mathrm{Y\_tos\_infinity}-\mathrm{Y\_tos}}{\mathrm{tau\_Y\_tos}}$ $\frac{1}{1+e^{\frac{V+33.5}{10}}}$ $\frac{3000}{1+e^{\frac{V+60}{10}}}+30$ $\frac{\mathrm{R\_tos\_infinity}-\mathrm{R\_tos}}{\mathrm{tau\_R\_tos}}$ $\frac{1}{1+e^{\frac{V+33.5}{10}}}$ $\mathrm{R\_tos\_infinity}$ $\frac{2.8E3}{1+e^{\frac{V+60}{10}}}+220$ $\mathrm{G\_tos}\mathrm{X\_tos}(\mathrm{Y\_tos}+0.5\mathrm{R\_tos})(V-\mathrm{E\_K})$ $\frac{\mathrm{X\_tof\_infinity}-\mathrm{X\_tof}}{\mathrm{tau\_X\_tof}}$ $\frac{1}{1+e^{\frac{-(V+3)}{15}}}$ $3.5e^{-\left(\frac{V}{30}\right)^2}+1.5$ $\frac{\mathrm{Y\_tof\_infinity}-\mathrm{Y\_tof}}{\mathrm{tau\_Y\_tof}}$ $\frac{1}{1+e^{\frac{V+33.5}{10}}}$ $\frac{20}{1+e^{\frac{V+33.5}{10}}}+20$ $\mathrm{G\_tof}\mathrm{X\_tof}\mathrm{Y\_tof}(V-\mathrm{E\_K})$ $\frac{\mathrm{alpha\_K1}}{\mathrm{alpha\_K1}+\mathrm{beta\_K1}}$ $\frac{1.02}{1+e^{0.2385(V-\mathrm{E\_K}+59.215)}}$ $\frac{0.49124e^{0.08032(V-\mathrm{E\_K}+5.476)}+1e^{0.06175(V-\mathrm{E\_K}+594.31)}}{1+e^{-0.5143(V-\mathrm{E\_K}+4.753)}}$ $\mathrm{G\_K1}\mathrm{K1\_infinity}(V-\mathrm{E\_K})$ $0.9\sqrt{\frac{\mathrm{Ko}}{5.4}}$ $\frac{\mathrm{g\_Kp}(V-\mathrm{E\_K})}{1+e^{7.488-\frac{V}{5.98}}}$ $\mathrm{G\_Cl}(V-\mathrm{E\_Cl})(\frac{\mathrm{Fx\_Cl\_jct}}{1+\frac{\mathrm{Kd\_ClCa}}{\mathrm{Ca\_jct}}}+\frac{\mathrm{Fx\_Cl\_SL}}{1+\frac{\mathrm{Kd\_ClCa}}{\mathrm{Ca\_SL}}})$ $\mathrm{G\_ClBk}(V-\mathrm{E\_Cl})$ $\frac{\mathrm{d\_infinity}-d}{\mathrm{tau\_d}}$ $\frac{1}{1+e^{\frac{-(V+14.5)}{6}}}$ $\frac{1\mathrm{d\_infinity}(1-e^{\frac{-(V+14.5)}{6}})}{0.035(V+14.5)}$ $\frac{\mathrm{f\_infinity}-f}{\mathrm{tau\_f}}$ $\frac{1}{1+e^{\frac{V+35.06}{3.6}}}+\frac{0.6}{1+e^{\frac{50-V}{20}}}$ $\frac{1}{0.0197e^{-(0.0337(V+14.5))^2}+0.02}$ $1-\mathrm{fCaB\_SL}$ $1-\mathrm{fCaB\_jct}$ $1.7\mathrm{Ca\_SL}(1-\mathrm{fCaB\_SL})-11.9\mathrm{fCaB\_SL}$ $1.7\mathrm{Ca\_jct}(1-\mathrm{fCaB\_jct})-11.9\mathrm{fCaB\_jct}$ $\mathrm{i\_CaL\_Ca\_SL}+\mathrm{i\_CaL\_Ca\_jct}+\mathrm{i\_CaL\_Na\_SL}+\mathrm{i\_CaL\_Na\_jct}+\mathrm{i\_CaL\_K}$ $\frac{\mathrm{temp}\mathrm{fCa\_SL}\mathrm{Fx\_ICaL\_SL}\mathrm{PCa}\times 4(\mathrm{gamma\_Cai}\mathrm{Ca\_SL}e^{\frac{2VF}{RT}}-\mathrm{gamma\_Cao}\mathrm{Cao})}{e^{\frac{2VF}{RT}}-1}$ $\frac{\mathrm{temp}\mathrm{fCa\_jct}\mathrm{Fx\_ICaL\_jct}\mathrm{PCa}\times 4(\mathrm{gamma\_Cai}\mathrm{Ca\_jct}e^{\frac{2VF}{RT}}-\mathrm{gamma\_Cao}\mathrm{Cao})}{e^{\frac{2VF}{RT}}-1}$ $\frac{\mathrm{temp}\mathrm{fCa\_SL}\mathrm{Fx\_ICaL\_SL}\mathrm{PNa}(\mathrm{gamma\_Nai}\mathrm{Na\_SL}e^{\frac{VF}{RT}}-\mathrm{gamma\_Nao}\mathrm{Nao})}{e^{\frac{VF}{RT}}-1}$ $\frac{\mathrm{temp}\mathrm{fCa\_jct}\mathrm{Fx\_ICaL\_jct}\mathrm{PNa}(\mathrm{gamma\_Nai}\mathrm{Na\_jct}e^{\frac{VF}{RT}}-\mathrm{gamma\_Nao}\mathrm{Nao})}{e^{\frac{VF}{RT}}-1}$ $\frac{\mathrm{temp}(\mathrm{fCa\_SL}\mathrm{Fx\_ICaL\_SL}+\mathrm{fCa\_jct}\mathrm{Fx\_ICaL\_jct})\mathrm{PK}(\mathrm{gamma\_Ki}\mathrm{Ki}e^{\frac{VF}{RT}}-\mathrm{gamma\_Ko}\mathrm{Ko})}{e^{\frac{VF}{RT}}-1}$ $\mathrm{Q10\_CaL}^{\left(\frac{T-310}{10}\right)}$ $\frac{df\mathrm{Q\_CaL}VF^2}{RT}$ $\mathrm{i\_NaCa\_jct}+\mathrm{i\_NaCa\_SL}$ $\frac{\mathrm{Fx\_NCX\_SL}\mathrm{V\_max}\mathrm{Ka\_SL}\mathrm{Q\_NCX}\mathrm{temp\_SL}}{\mathrm{K\_mCai}\mathrm{Nao}^{\mathrm{HNa}}(1+\left(\frac{\mathrm{Na\_SL}}{\mathrm{K\_mNai}}\right)^{\mathrm{HNa}})+\mathrm{K\_mNao}^{\mathrm{HNa}}\mathrm{Ca\_SL}(1+\frac{\mathrm{Ca\_SL}}{\mathrm{K\_mCai}})+\mathrm{K\_mCao}\mathrm{Na\_SL}^{\mathrm{HNa}}+\mathrm{Na\_SL}^{\mathrm{HNa}}\mathrm{Cao}+\mathrm{Nao}^{\mathrm{HNa}}\mathrm{Ca\_SL}}$ $\frac{\mathrm{Fx\_NCX\_jct}\mathrm{V\_max}\mathrm{Ka\_jct}\mathrm{Q\_NCX}\mathrm{temp\_jct}}{\mathrm{K\_mCai}\mathrm{Nao}^{\mathrm{HNa}}(1+\left(\frac{\mathrm{Na\_jct}}{\mathrm{K\_mNai}}\right)^{\mathrm{HNa}})+\mathrm{K\_mNao}^{\mathrm{HNa}}\mathrm{Ca\_jct}(1+\frac{\mathrm{Ca\_jct}}{\mathrm{K\_mCai}})+\mathrm{K\_mCao}\mathrm{Na\_jct}^{\mathrm{HNa}}+\mathrm{Na\_jct}^{\mathrm{HNa}}\mathrm{Cao}+\mathrm{Nao}^{\mathrm{HNa}}\mathrm{Ca\_jct}}$ $\mathrm{Q10\_NCX}^{\left(\frac{T-310}{10}\right)}$ $\frac{1}{1+\left(\frac{\mathrm{Kd\_act}}{\mathrm{Ca\_SL}}\right)^3}$ $\frac{1}{1+\left(\frac{\mathrm{Kd\_act}}{\mathrm{Ca\_jct}}\right)^3}$ $\frac{e^{\frac{\mathrm{eta}VF}{RT}}\mathrm{Na\_jct}^{\mathrm{HNa}}\mathrm{Cao}-e^{\frac{(\mathrm{eta}-1)VF}{RT}}\mathrm{Nao}^{\mathrm{HNa}}\mathrm{Ca\_jct}}{1+\mathrm{ksat}e^{\frac{(\mathrm{eta}-1)VF}{RT}}}$ $\frac{e^{\frac{\mathrm{eta}VF}{RT}}\mathrm{Na\_SL}^{\mathrm{HNa}}\mathrm{Cao}-e^{\frac{(\mathrm{eta}-1)VF}{RT}}\mathrm{Nao}^{\mathrm{HNa}}\mathrm{Ca\_SL}}{1+\mathrm{ksat}e^{\frac{(\mathrm{eta}-1)VF}{RT}}}$ $\mathrm{i\_Cap\_jct}+\mathrm{i\_Cap\_SL}$ $\frac{\mathrm{Q\_SLCaP}\mathrm{V\_maxAF}\mathrm{Fx\_SLCaP\_SL}}{1+\left(\frac{\mathrm{Km}}{\mathrm{Ca\_SL}}\right)^H}$ $\frac{\mathrm{Q\_SLCaP}\mathrm{V\_maxAF}\mathrm{Fx\_SLCaP\_jct}}{1+\left(\frac{\mathrm{Km}}{\mathrm{Ca\_jct}}\right)^H}$ $\mathrm{Q10\_SLCaP}^{\left(\frac{T-310}{10}\right)}$ $\frac{\mathrm{V\_max}\mathrm{Vol\_cytosol}\times 2F}{\mathrm{Cm}}$ $\mathrm{i\_Cab\_SL}+\mathrm{i\_Cab\_jct}$ $\mathrm{G\_CaBk}\mathrm{Fx\_CaBk\_jct}(V-\mathrm{E\_Ca\_jct})$ $\mathrm{G\_CaBk}\mathrm{Fx\_CaBk\_SL}(V-\mathrm{E\_Ca\_SL})$ $\mathrm{ks}O(\mathrm{Ca\_SR}-\mathrm{Ca\_jct})$ $\mathrm{kim}\mathrm{RI}-\mathrm{kiSRCa}\mathrm{Ca\_jct}R-\mathrm{koSRCa}\mathrm{Ca\_jct}^{2}R-\mathrm{kom}O$ $\mathrm{kiSRCa}\mathrm{Ca\_jct}O-\mathrm{kim}I-\mathrm{kom}I-\mathrm{koSRCa}\mathrm{Ca\_jct}^2\mathrm{RI}$ $1-R-O-I$ $\mathrm{koSRCa}\mathrm{Ca\_jct}^{2}R-\mathrm{kom}O-\mathrm{kiSRCa}\mathrm{Ca\_jct}O-\mathrm{kim}I$ $\mathrm{Max\_SR}-\frac{\mathrm{Max\_SR}-\mathrm{Min\_SR}}{1+\left(\frac{\mathrm{EC50\_SR}}{\mathrm{Ca\_SR}}\right)^{\mathrm{HSR}}}$ $\frac{\mathrm{koCa}}{\mathrm{kCaSR}}$ $\mathrm{kiCa}\mathrm{kCaSR}$ $\mathrm{KSRleak}(\mathrm{Ca\_SR}-\mathrm{Ca\_jct})$ $\frac{\frac{\mathrm{Q\_SRCaP}\mathrm{V\_max}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_SR}}(\left(\frac{\mathrm{Cai}}{\mathrm{Kmf}}\right)^H-\left(\frac{\mathrm{Ca\_SR}}{\mathrm{Kmr}}\right)^H)}{1+\left(\frac{\mathrm{Cai}}{\mathrm{Kmf}}\right)^H+\left(\frac{\mathrm{Ca\_SR}}{\mathrm{Kmr}}\right)^H}$ $\mathrm{Q10\_SRCaP}^{\left(\frac{T-310}{10}\right)}$ $(\mathrm{Na\_jct}-\mathrm{Na\_SL})\mathrm{j\_Na\_jct\_SL}$ $(\mathrm{Na\_SL}-\mathrm{Nai})\mathrm{j\_Na\_SL\_cytosol}$ $(\mathrm{Ca\_jct}-\mathrm{Ca\_SL})\mathrm{j\_Ca\_jct\_SL}$ $(\mathrm{Ca\_SL}-\mathrm{Cai})\mathrm{j\_Ca\_SL\_cytosol}$ $\frac{\mathrm{D\_Na\_jct\_SL}\mathrm{A\_jct\_SL}}{\mathrm{x\_jct\_SL}}$ $\frac{\mathrm{D\_Na\_SL\_cytosol}\mathrm{A\_SL\_cytosol}}{\mathrm{x\_SL\_cytosol}}$ $\frac{\mathrm{D\_Ca\_jct\_SL}\mathrm{A\_jct\_SL}}{\mathrm{x\_jct\_SL}}$ $\frac{\mathrm{D\_Ca\_SL\_cytosol}\mathrm{A\_SL\_cytosol}}{\mathrm{x\_SL\_cytosol}}$ $1.8313E-14$ $1.6386E-12$ $8.2413E-13$ $3.7243E-12$ $\frac{-\mathrm{Cm}(\mathrm{i\_Na\_SL}+3\mathrm{i\_NaCa\_SL}+\mathrm{i\_Nab\_SL}+3\mathrm{i\_NaK\_SL}+\mathrm{i\_CaL\_Na\_SL})}{\mathrm{Vol\_SL}F}+\frac{\mathrm{J\_Na\_jct\_SL}-\mathrm{J\_Na\_SL\_cytosol}}{\mathrm{Vol\_SL}}-\mathrm{dNa\_SL\_buf}$ $\frac{-\mathrm{Cm}(\mathrm{i\_Na\_jct}+3\mathrm{i\_NaCa\_jct}+\mathrm{i\_Nab\_jct}+3\mathrm{i\_NaK\_jct}+\mathrm{i\_CaL\_Na\_jct})}{\mathrm{Vol\_jct}F}-\frac{\mathrm{J\_Na\_jct\_SL}}{\mathrm{Vol\_jct}}-\mathrm{dNa\_jct\_buf}$ $\mathrm{dNa\_SL\_buf}$ $\mathrm{dNa\_jct\_buf}$ $\frac{\mathrm{J\_Na\_SL\_cytosol}}{\mathrm{Vol\_cytosol}}$ $\mathrm{kon}\mathrm{Na\_jct}(\mathrm{Bmax\_jct}-\mathrm{Na\_jct\_buf})-\mathrm{koff}\mathrm{Na\_jct\_buf}$ $\mathrm{kon}\mathrm{Na\_SL}(\mathrm{Bmax\_SL}-\mathrm{Na\_SL\_buf})-\mathrm{koff}\mathrm{Na\_SL\_buf}$ $\mathrm{dCa\_TroponinC}$ $\mathrm{dCa\_TroponinC\_Ca\_Mg}$ $\mathrm{dMg\_TroponinC\_Ca\_Mg}$ $\mathrm{dCa\_Calmodulin}$ $\mathrm{dCa\_Myosin}$ $\mathrm{dMg\_Myosin}$ $\mathrm{dCa\_SRB}$ $\mathrm{kon\_TroponinC}\mathrm{Cai}(\mathrm{Bmax\_TroponinC}-\mathrm{Ca\_TroponinC})-\mathrm{koff\_TroponinC}\mathrm{Ca\_TroponinC}$ $\mathrm{kon\_TroponinC\_Ca\_Mg\_Ca}\mathrm{Cai}(\mathrm{Bmax\_TroponinC\_Ca\_Mg\_Ca}-\mathrm{Ca\_TroponinC\_Ca\_Mg}+\mathrm{Mg\_TroponinC\_Ca\_Mg})-\mathrm{koff\_TroponinC\_Ca\_Mg\_Ca}\mathrm{Ca\_TroponinC\_Ca\_Mg}$ $\mathrm{kon\_TroponinC\_Ca\_Mg\_Mg}\mathrm{Mgi}(\mathrm{Bmax\_TroponinC\_Ca\_Mg\_Mg}-\mathrm{Ca\_TroponinC\_Ca\_Mg}+\mathrm{Mg\_TroponinC\_Ca\_Mg})-\mathrm{koff\_TroponinC\_Ca\_Mg\_Mg}\mathrm{Mg\_TroponinC\_Ca\_Mg}$ $\mathrm{kon\_Calmodulin}\mathrm{Cai}(\mathrm{Bmax\_Calmodulin}-\mathrm{Ca\_Calmodulin})-\mathrm{koff\_Calmodulin}\mathrm{Ca\_Calmodulin}$ $\mathrm{kon\_Myosin\_Ca}\mathrm{Cai}(\mathrm{Bmax\_Myosin\_Ca}-\mathrm{Ca\_Myosin}+\mathrm{Mg\_Myosin})-\mathrm{koff\_Myosin\_Ca}\mathrm{Ca\_Myosin}$ $\mathrm{kon\_Myosin\_Mg}\mathrm{Mgi}(\mathrm{Bmax\_Myosin\_Mg}-\mathrm{Ca\_Myosin}+\mathrm{Mg\_Myosin})-\mathrm{koff\_Myosin\_Mg}\mathrm{Mg\_Myosin}$ $\mathrm{kon\_SRB}\mathrm{Cai}(\mathrm{Bmax\_SRB}-\mathrm{Ca\_SRB})-\mathrm{koff\_SRB}\mathrm{Ca\_SRB}$ $\mathrm{dCa\_TroponinC}+\mathrm{dCa\_TroponinC\_Ca\_Mg}+\mathrm{dMg\_TroponinC\_Ca\_Mg}+\mathrm{dCa\_Calmodulin}+\mathrm{dCa\_Myosin}+\mathrm{dMg\_Myosin}+\mathrm{dCa\_SRB}$ $\mathrm{dCa\_Indo1\_Cytosol}$ $\mathrm{dCa\_Indo1\_SL}$ $\mathrm{dCa\_Indo1\_jct}$ $\mathrm{dCa\_Fluo3\_Cytosol}$ $\mathrm{dCa\_Fluo3\_SL}$ $\mathrm{dCa\_Fluo3\_jct}$ $\mathrm{Ca\_Indo1\_Cytosol}+\frac{\mathrm{Ca\_Indo1\_jct}\mathrm{Vol\_jct}}{\mathrm{Vol\_cytosol}}+\frac{\mathrm{Ca\_Indo1\_SL}\mathrm{Vol\_SL}}{\mathrm{Vol\_cytosol}}$ $\mathrm{Ca\_Fluo3\_Cytosol}+\frac{\mathrm{Ca\_Fluo3\_jct}\mathrm{Vol\_jct}}{\mathrm{Vol\_cytosol}}+\frac{\mathrm{Ca\_Fluo3\_SL}\mathrm{Vol\_SL}}{\mathrm{Vol\_cytosol}}$ $\mathrm{kon\_Indo1}(\mathrm{Indo1}-\mathrm{Indo1Bound})\mathrm{Cai}(\mathrm{Bmax\_Indo1\_Cytosol}-\mathrm{Ca\_Indo1\_Cytosol})-\mathrm{koff\_Indo1}\mathrm{Ca\_Indo1\_Cytosol}$ $\mathrm{kon\_Indo1}(\mathrm{Indo1}-\mathrm{Indo1Bound})\mathrm{Ca\_jct}(\frac{\mathrm{Bmax\_Indo1\_jct}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_jct}}-\mathrm{Ca\_Indo1\_jct})-\mathrm{koff\_Indo1}\mathrm{Ca\_Indo1\_jct}$ $\mathrm{kon\_Indo1}(\mathrm{Indo1}-\mathrm{Indo1Bound})\mathrm{Ca\_SL}(\frac{\mathrm{Bmax\_Indo1\_SL}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_SL}}-\mathrm{Ca\_Indo1\_SL})-\mathrm{koff\_Indo1}\mathrm{Ca\_Indo1\_SL}$ $\mathrm{kon\_Fluo3}(\mathrm{Fluo3}-\mathrm{Fluo3Bound})\mathrm{Cai}(\mathrm{Bmax\_Fluo3\_Cytosol}-\mathrm{Ca\_Fluo3\_Cytosol})-\mathrm{koff\_Fluo3}\mathrm{Ca\_Fluo3\_Cytosol}$ $\mathrm{kon\_Fluo3}(\mathrm{Fluo3}-\mathrm{Fluo3Bound})\mathrm{Ca\_jct}(\frac{\mathrm{Bmax\_Fluo3\_jct}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_jct}}-\mathrm{Ca\_Fluo3\_jct})-\mathrm{koff\_Fluo3}\mathrm{Ca\_Fluo3\_jct}$ $\mathrm{kon\_Fluo3}(\mathrm{Fluo3}-\mathrm{Fluo3Bound})\mathrm{Ca\_SL}(\frac{\mathrm{Bmax\_Fluo3\_SL}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_SL}}-\mathrm{Ca\_Fluo3\_SL})-\mathrm{koff\_Fluo3}\mathrm{Ca\_Fluo3\_SL}$ $\mathrm{j\_pump\_SR}-\frac{\mathrm{j\_leak\_SR}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_SR}}+\mathrm{j\_rel\_SR}-\mathrm{dCalsequestrin}$ $\frac{-\mathrm{i\_Ca\_SL\_tot}\mathrm{Cm}}{\mathrm{Vol\_SL}\times 2F}+\frac{\mathrm{J\_Ca\_jct\_SL}-\mathrm{J\_Ca\_SL\_cytosol}}{\mathrm{Vol\_SL}}-1\mathrm{dCa\_SL\_tot\_bound}$ $\frac{-\mathrm{i\_Ca\_jct\_tot}\mathrm{Cm}}{\mathrm{Vol\_jct}\times 2F}-\frac{\mathrm{J\_Ca\_jct\_SL}}{\mathrm{Vol\_jct}}+\frac{\mathrm{j\_rel\_SR}\mathrm{Vol\_SR}}{\mathrm{Vol\_jct}}+\frac{\mathrm{j\_leak\_SR}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_jct}}-1\mathrm{dCa\_jct\_tot\_bound}$ $\frac{-\mathrm{j\_pump\_SR}\mathrm{Vol\_SR}}{\mathrm{Vol\_cytosol}}+\frac{\mathrm{J\_Ca\_SL\_cytosol}}{\mathrm{Vol\_cytosol}}-1\mathrm{dCa\_cytosol\_tot\_bound}$ $\mathrm{dCa\_SLB\_SL}$ $\mathrm{dCa\_SLB\_jct}$ $\mathrm{dCa\_SLHigh\_SL}$ $\mathrm{dCa\_SLHigh\_jct}$ $\mathrm{dCalsequestrin}$ $\mathrm{kon\_Calsequestrin}\mathrm{Ca\_SR}(\frac{\mathrm{Bmax\_Calsequestrin}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_SR}}-\mathrm{Ca\_Calsequestrin})-\mathrm{koff\_Calsequestrin}\mathrm{Ca\_Calsequestrin}$ $\mathrm{kon\_SL}\mathrm{Ca\_SL}(\frac{\mathrm{Bmax\_SLB\_SL}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_SL}}-\mathrm{Ca\_SLB\_SL})-\mathrm{koff\_SLB}\mathrm{Ca\_SLB\_SL}$ $\mathrm{kon\_SL}\mathrm{Ca\_jct}(\frac{\mathrm{Bmax\_SLB\_jct}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_jct}}-\mathrm{Ca\_SLB\_jct})-\mathrm{koff\_SLB}\mathrm{Ca\_SLB\_jct}$ $\mathrm{kon\_SL}\mathrm{Ca\_SL}(\frac{\mathrm{Bmax\_SLHigh\_SL}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_SL}}-\mathrm{Ca\_SLHigh\_SL})-\mathrm{koff\_SLHigh}\mathrm{Ca\_SLHigh\_SL}$ $\mathrm{kon\_SL}\mathrm{Ca\_jct}(\frac{\mathrm{Bmax\_SLHigh\_jct}\mathrm{Vol\_cytosol}}{\mathrm{Vol\_jct}}-\mathrm{Ca\_SLHigh\_jct})-\mathrm{koff\_SLHigh}\mathrm{Ca\_SLHigh\_jct}$ $\mathrm{dCa\_SLB\_jct}+\mathrm{dCa\_SLHigh\_jct}$ $\mathrm{dCa\_SLB\_SL}+\mathrm{dCa\_SLHigh\_SL}$ $\mathrm{i\_CaL\_Ca\_jct}-2\mathrm{i\_NaCa\_jct}+\mathrm{i\_Cab\_jct}+\mathrm{i\_Cap\_jct}$ $\mathrm{i\_CaL\_Ca\_SL}-2\mathrm{i\_NaCa\_SL}+\mathrm{i\_Cab\_SL}+\mathrm{i\_Cap\_SL}$