//Created by libAntimony v2.4
model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__environment(time_)

  // Variable initializations:
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__NatP(NatP, v1, v2, v5, time_)

  // Rate Rules:
  NatP' = (v1 + v5) - v2;

  // Variable initializations:
  NatP = 6000000;
  v1 = ;
  v2 = ;
  v5 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__MisP(MisP, v2, v3, v4, v6, v7, time_)

  // Rate Rules:
  MisP' = (v2 + v4) - (v3 + v6 + 2 * v7);

  // Variable initializations:
  MisP = 0;
  v2 = ;
  v3 = ;
  v4 = ;
  v6 = ;
  v7 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__MCom(MCom, v3, v4, v5, time_)

  // Rate Rules:
  MCom' = v3 - (v4 + v5);

  // Variable initializations:
  MCom = 0;
  v3 = ;
  v4 = ;
  v5 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__Hsp90(Hsp90, v5, v4, v9, v16, v3, v8, v17, time_)

  // Rate Rules:
  Hsp90' = (v5 + v4 + v9 + v16) - (v3 + v8 + v17);

  // Variable initializations:
  Hsp90 = 300000;
  v5 = ;
  v4 = ;
  v9 = ;
  v16 = ;
  v3 = ;
  v8 = ;
  v17 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__HCom(HCom, v8, v9, time_)

  // Rate Rules:
  HCom' = v8 - v9;

  // Variable initializations:
  HCom = 5900;
  v8 = ;
  v9 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__HSF1(HSF1, v13, v12, v8, v9, v10, v11, time_)

  // Rate Rules:
  HSF1' = (v9 + 2 * v13 + v12) - (v8 + 2 * v10 + v11);

  // Variable initializations:
  HSF1 = 100;
  v13 = ;
  v12 = ;
  v8 = ;
  v9 = ;
  v10 = ;
  v11 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__DiH(DiH, v10, v11, v12, v13, time_)

  // Rate Rules:
  DiH' = (v10 + v12) - (v11 + v13);

  // Variable initializations:
  DiH = 0;
  v10 = ;
  v11 = ;
  v12 = ;
  v13 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__TriH(TriH, v11, v12, v14, v15, time_)

  // Rate Rules:
  TriH' = (v11 + v15) - (v12 + v14);

  // Variable initializations:
  TriH = 0;
  v11 = ;
  v12 = ;
  v14 = ;
  v15 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__HSE_TriH(HSE_TriH, v14, v15, v16, time_)

  // Rate Rules:
  HSE_TriH' = (v14 + v16) - (v15 + v16);

  // Variable initializations:
  HSE_TriH = 0;
  v14 = ;
  v15 = ;
  v16 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__HSE(HSE, v14, v15, time_)

  // Rate Rules:
  HSE' = v15 - v14;

  // Variable initializations:
  HSE = 1;
  v14 = ;
  v15 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__AggP(AggP, v7, v7b, time_)

  // Rate Rules:
  AggP' = (v7 + 2 * v7b) - v7b;

  // Variable initializations:
  AggP = 0;
  v7 = ;
  v7b = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__ROS(ROS, v2, v20, v21, time_)

  // Rate Rules:
  ROS' = (v2 + v20) - (v2 + v21);

  // Variable initializations:
  ROS = 100;
  v2 = ;
  v20 = ;
  v21 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__ATP(ATP, v5, v6, v17, v18, v19, time_)

  // Rate Rules:
  ATP' = v18 - (v5 + v6 + v17 + v19);

  // Variable initializations:
  ATP = 10000;
  v5 = ;
  v6 = ;
  v17 = ;
  v18 = ;
  v19 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__ADP(ADP, v5, v6, v17, v18, v19, time_)

  // Rate Rules:
  ADP' = (v5 + v6 + v17 + v19) - v18;

  // Variable initializations:
  ADP = 1000;
  v5 = ;
  v6 = ;
  v17 = ;
  v18 = ;
  v19 = ;
  time_ = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v1(v1)

  // Assignment Rules:
  v1 := k1;

  // Variable initializations:
  k1 = 10;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v2(v2, NatP, ROS)

  // Assignment Rules:
  v2 := k2 * NatP * ROS;

  // Variable initializations:
  k2 = 0.00002;
  NatP = ;
  ROS = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v3(v3, MisP, Hsp90)

  // Assignment Rules:
  v3 := k3 * MisP * Hsp90;

  // Variable initializations:
  k3 = 50;
  MisP = ;
  Hsp90 = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v4(v4, MCom)

  // Assignment Rules:
  v4 := k4 * MCom;

  // Variable initializations:
  k4 = 0.00001;
  MCom = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v5(v5, MCom, ATP)

  // Assignment Rules:
  v5 := k5 * MCom * ATP;

  // Variable initializations:
  k5 = 4e-6;
  MCom = ;
  ATP = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v6(v6, MisP, ATP)

  // Assignment Rules:
  v6 := k6 * MisP * ATP;

  // Variable initializations:
  k6 = 6e-7;
  MisP = ;
  ATP = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v7(v7, MisP)

  // Assignment Rules:
  v7 := k7 * MisP * MisP;

  // Variable initializations:
  k7 = 1e-7;
  MisP = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v7b(v7b, MisP, AggP)

  // Assignment Rules:
  v7b := k7 * MisP * AggP;

  // Variable initializations:
  k7 = 1e-7;
  MisP = ;
  AggP = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v8(v8, HSF1, Hsp90)

  // Assignment Rules:
  v8 := k8 * HSF1 * Hsp90;

  // Variable initializations:
  k8 = 500;
  HSF1 = ;
  Hsp90 = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v9(v9, HCom)

  // Assignment Rules:
  v9 := k9 * HCom;

  // Variable initializations:
  k9 = 1;
  HCom = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v10(v10, HSF1)

  // Assignment Rules:
  v10 := k10 * HSF1 * HSF1;

  // Variable initializations:
  k10 = 0.01;
  HSF1 = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v11(v11, HSF1, DiH)

  // Assignment Rules:
  v11 := k11 * DiH * HSF1;

  // Variable initializations:
  k11 = 100;
  HSF1 = ;
  DiH = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v12(v12, TriH)

  // Assignment Rules:
  v12 := k12 * TriH;

  // Variable initializations:
  k12 = 0.5;
  TriH = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v13(v13, DiH)

  // Assignment Rules:
  v13 := k13 * DiH;

  // Variable initializations:
  k13 = 0.5;
  DiH = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v14(v14, HSE, TriH)

  // Assignment Rules:
  v14 := k14 * HSE * TriH;

  // Variable initializations:
  k14 = 0.05;
  HSE = ;
  TriH = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v15(v15, HSE_TriH)

  // Assignment Rules:
  v15 := k15 * HSE_TriH;

  // Variable initializations:
  k15 = 0.08;
  HSE_TriH = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v16(v16, HSE_TriH)

  // Assignment Rules:
  v16 := k16 * HSE_TriH;

  // Variable initializations:
  k16 = 1000;
  HSE_TriH = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v17(v17, Hsp90, ATP)

  // Assignment Rules:
  v17 := k17 * Hsp90 * ATP;

  // Variable initializations:
  k17 = 8.02e-9;
  Hsp90 = ;
  ATP = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v18(v18, ADP)

  // Assignment Rules:
  v18 := k18 * ADP;

  // Variable initializations:
  k18 = 12;
  ADP = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v19(v19, ATP)

  // Assignment Rules:
  v19 := k19 * ATP;

  // Variable initializations:
  k19 = 0.02;
  ATP = ;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v20(v20)

  // Assignment Rules:
  v20 := k20;

  // Variable initializations:
  k20 = 0.1;
end

model proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v21(v21, ROS)

  // Assignment Rules:
  v21 := k21 * ROS;

  // Variable initializations:
  k21 = 0.00001;
  ROS = ;
end

model *proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005____main()

  // Sub-modules, and any changes to those submodules:
  environment: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__environment(time_);
  NatP: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__NatP(NatP0, v110, v22, v50, time_);
  MisP: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__MisP(MisP0, v22, v30, v40, v60, v70, time_);
  MCom: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__MCom(MCom0, v30, v40, v50, time_);
  Hsp90: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__Hsp90(Hsp900, v50, v40, v90, v160, v30, v80, v170, time_);
  HCom: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__HCom(HCom0, v80, v90, time_);
  HSF1: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__HSF1(HSF10, v130, v120, v80, v90, v100, v111, time_);
  DiH: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__DiH(DiH0, v100, v111, v120, v130, time_);
  TriH: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__TriH(TriH0, v111, v120, v140, v150, time_);
  HSE_TriH: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__HSE_TriH(HSE_TriH0, v140, v150, v160, time_);
  HSE: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__HSE(HSE0, v140, v150, time_);
  AggP: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__AggP(AggP0, v70, v7b0, time_);
  ROS: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__ROS(ROS0, v22, v200, v210, time_);
  ATP: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__ATP(ATP0, v50, v60, v170, v180, v190, time_);
  ADP: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__ADP(ADP0, v50, v60, v170, v180, v190, time_);
  v1: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v1(v110);
  v2: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v2(v22, NatP0, ROS0);
  v3: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v3(v30, MisP0, Hsp900);
  v4: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v4(v40, MCom0);
  v5: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v5(v50, MCom0, ATP0);
  v6: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v6(v60, MisP0, ATP0);
  v7: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v7(v70, MisP0);
  v7b: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v7b(v7b0, MisP0, AggP0);
  v8: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v8(v80, HSF10, Hsp900);
  v9: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v9(v90, HCom0);
  v10: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v10(v100, HSF10);
  v11: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v11(v111, HSF10, DiH0);
  v12: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v12(v120, TriH0);
  v13: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v13(v130, DiH0);
  v14: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v14(v140, HSE0, TriH0);
  v15: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v15(v150, HSE_TriH0);
  v16: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v16(v160, HSE_TriH0);
  v17: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v17(v170, Hsp900, ATP0);
  v18: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v18(v180, ADP0);
  v19: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v19(v190, ATP0);
  v20: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v20(v200);
  v21: proctor_soti_boys_gillespie_shanley_wilkinson_kirkwood_2005__v21(v210, ROS0);
end