$-\mathrm{flux\_GP}$ $\mathrm{flux\_GP}-\mathrm{V\_PGLM}$ $\mathrm{V\_PGLM}-\mathrm{V\_PGI}$ $\mathrm{V\_PGI}-\mathrm{V\_PFK}$ $\mathrm{V\_PFK}-\mathrm{V\_ALD}$ $\mathrm{V\_ALD}+\mathrm{V\_TPI}$ $\mathrm{V\_ALD}-\mathrm{V\_TPI}+\mathrm{V\_GAPDH}$ $\mathrm{V\_GAPDH}-\mathrm{V\_PGK}$ $\mathrm{V\_PGK}-\mathrm{V\_PGM}$ $\mathrm{V\_PGM}-\mathrm{V\_ENOL}$ $\mathrm{V\_ENOL}-\mathrm{V\_PK}$ $\mathrm{V\_PK}-\mathrm{V\_LDH}$ $\mathrm{V\_LDH}-\mathrm{output}$ $0.2\mathrm{LAC}$ $\mathrm{V\_ATPase}-\mathrm{flux\_GP}+\mathrm{V\_GAPDH}$ $\mathrm{V\_PFK}+2\mathrm{V\_ADK}+\mathrm{V\_CK}+\mathrm{V\_ATPase}+-(\mathrm{V\_PGK}+\mathrm{V\_PK})$ $\mathrm{V\_PGK}+\mathrm{V\_PK}+-(\mathrm{V\_PFK}+\mathrm{V\_ADK}+\mathrm{V\_CK}+\mathrm{V\_ATPase})$ $-\mathrm{V\_ADK}$ $\mathrm{V\_CK}$ $-\mathrm{V\_CK}$ $\mathrm{V\_GAPDH}-\mathrm{V\_LDH}$ $\mathrm{V\_LDH}-\mathrm{V\_GAPDH}$ $\mathrm{frac\_a}\mathrm{V\_GPa}+\mathrm{frac\_b}\mathrm{V\_GPb}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{GLY}\mathrm{Pi\_}}{\mathrm{Ki\_GLY\_f}\mathrm{K\_Pi}}-\mathrm{V\_max\_r}\frac{\mathrm{GLY}\mathrm{G1P}}{\mathrm{Ki\_GLY\_b}\mathrm{Ki\_G1P}}}{1+\frac{\mathrm{GLY}}{\mathrm{Ki\_GLY\_f}}+\frac{\mathrm{Pi\_}}{\mathrm{Ki\_Pi}}+\frac{\mathrm{GLY}}{\mathrm{Ki\_GLY\_b}}+\frac{\mathrm{G1P}}{\mathrm{Ki\_G1P}}+\frac{\mathrm{GLY}\mathrm{Pi\_}}{\mathrm{K\_GLY\_f}\mathrm{Ki\_Pi}}+\frac{\mathrm{GLY}\mathrm{G1P}}{\mathrm{K\_GLY\_b}\mathrm{Ki\_G1P}}}$ $\frac{\mathrm{V\_max\_f}\mathrm{K\_GLY\_b}\mathrm{Ki\_G1P}}{\mathrm{Ki\_GLY\_f}\mathrm{K\_Pi}\mathrm{Keq\_GP}}$ $1.9E-6$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{GLY}\mathrm{Pi\_}}{\mathrm{Ki\_GLY\_f}\mathrm{K\_Pi}}-\mathrm{V\_max\_r}\frac{\mathrm{GLY}\mathrm{G1P}}{\mathrm{Ki\_GLY\_b}\mathrm{Ki\_G1P}}}{1+\frac{\mathrm{GLY}}{\mathrm{Ki\_GLY\_f}}+\frac{\mathrm{Pi\_}}{\mathrm{Ki\_Pi}}+\frac{\mathrm{GLY}}{\mathrm{Ki\_GLY\_b}}+\frac{\mathrm{G1P}}{\mathrm{Ki\_G1P}}+\frac{\mathrm{GLY}\mathrm{Pi\_}}{\mathrm{K\_GLY\_f}\mathrm{Ki\_Pi}}+\frac{\mathrm{GLY}\mathrm{G1P}}{\mathrm{K\_GLY\_b}\mathrm{Ki\_G1P}}}\frac{\frac{\mathrm{AMP}^{\mathrm{nH}}}{\mathrm{K\_AMP}}}{1+\frac{\mathrm{AMP}^{\mathrm{nH}}}{\mathrm{K\_AMP}}}$ $\frac{\mathrm{V\_max\_f}\mathrm{Ki\_GLY\_b}\mathrm{K\_G1P}}{\mathrm{K\_GLY\_f}\mathrm{Ki\_Pi}\mathrm{Keq\_GP}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{G1P}}{\mathrm{K\_G1P}}-\mathrm{V\_max\_r}\frac{\mathrm{G6P}}{\mathrm{K\_G6P}}}{1+\frac{\mathrm{G1P}}{\mathrm{K\_G1P}}+\frac{\mathrm{G6P}}{\mathrm{K\_G6P}}}$ $\frac{\mathrm{V\_max\_f}\mathrm{K\_G6P}}{\mathrm{K\_G1P}\mathrm{Keq\_PGLM}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{G6P}}{\mathrm{K\_G6P}}-\mathrm{V\_max\_r}\frac{\mathrm{F6P}}{\mathrm{K\_F6P}}}{1+\frac{\mathrm{G6P}}{\mathrm{K\_G6P}}+\frac{\mathrm{F6P}}{\mathrm{K\_F6P}}}$ $\frac{\mathrm{V\_max\_r}\mathrm{K\_G6P}\mathrm{Keq\_PGI}}{\mathrm{K\_F6P}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{ATP}\mathrm{F6P}}{\mathrm{K\_ATP}\mathrm{K\_F6P}}-\mathrm{V\_max\_r}\frac{\mathrm{ADP}\mathrm{FBP}}{\mathrm{K\_ADP}\mathrm{K\_FBP}}}{\mathrm{delta}}\frac{1+\mathrm{alpha}L\left(\frac{\mathrm{delta\_}}{\mathrm{delta}}\right)^3}{1+L\left(\frac{\mathrm{delta\_}}{\mathrm{delta}}\right)^4}$ $\frac{\mathrm{V\_max\_f}\mathrm{K\_ADP}\mathrm{K\_FBP}}{\mathrm{K\_ATP}\mathrm{K\_F6P}}$ $\frac{\mathrm{K\_F6P}\mathrm{K\_ATP}}{\mathrm{K\_F6P\_}\mathrm{K\_ATP\_}}$ $\mathrm{Lo}(\frac{1+\frac{\mathrm{ATP}}{\mathrm{Ki\_ATP}}}{1+d\frac{\mathrm{ATP}}{\mathrm{Ki\_ATP}}}\frac{1+\mathrm{var\_e}\frac{\mathrm{AMP}}{\mathrm{Ka\_AMP}}}{1+\frac{\mathrm{AMP}}{\mathrm{Ka\_AMP}}})^4$ $(1+\frac{\mathrm{F6P}}{\mathrm{K\_F6P}})(1+\frac{\mathrm{ATP}}{\mathrm{K\_ATP}})+\frac{\mathrm{ADP}}{\mathrm{K\_ADP}}+\frac{\mathrm{FBP}}{\mathrm{K\_FBP}}(1+\frac{\mathrm{ADP}}{\mathrm{K\_ADP}})$ $(1+\frac{\mathrm{F6P}}{\mathrm{K\_F6P\_}})(1+\frac{\mathrm{ATP}}{\mathrm{K\_ATP\_}})+\frac{\mathrm{ADP}}{\mathrm{K\_ADP\_}}+\frac{\mathrm{FBP}}{\mathrm{K\_FBP\_}}(1+\frac{\mathrm{ADP}}{\mathrm{K\_ADP\_}})$ $9.5E-5$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{FBP}}{\mathrm{K\_FBP}}-\mathrm{V\_max\_r}\frac{\mathrm{DHAP}\mathrm{GAP}}{\mathrm{K\_DHAP}\mathrm{K\_GAP}}}{1+\frac{\mathrm{FBP}}{\mathrm{K\_FBP}}+\frac{\mathrm{DHAP}}{\mathrm{K\_DHAP}}+\frac{\mathrm{GAP}}{\mathrm{K\_GAP}}}$ $\frac{\mathrm{V\_max\_f}\mathrm{K\_DHAP}\mathrm{K\_GAP}}{\mathrm{K\_FBP}\mathrm{Keq\_ALD}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{GAP}}{\mathrm{K\_GAP}}-\mathrm{V\_max\_r}\frac{\mathrm{DHAP}}{\mathrm{K\_DHAP}}}{1+\frac{\mathrm{DHAP}}{\mathrm{K\_DHAP}}+\frac{\mathrm{GAP}}{\mathrm{K\_GAP}}}$ $\frac{\mathrm{V\_max\_f}\mathrm{K\_DHAP}}{\mathrm{K\_GAP}\mathrm{Keq\_TPI}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{GAP}\mathrm{NAD}\mathrm{Pi\_}}{\mathrm{K\_GAP}\mathrm{K\_NAD}\mathrm{K\_Pi}}-\mathrm{V\_max\_r}\frac{\mathrm{Thirteen\_BPG}\mathrm{NADH}}{\mathrm{K\_Thirteen\_BPG}\mathrm{K\_NADH}}}{\mathrm{D\_GAPDH}}$ $1+\frac{\mathrm{GAP}}{\mathrm{K\_GAP}}+\frac{\mathrm{NAD}}{\mathrm{K\_NAD}}+\frac{\mathrm{Pi\_}}{\mathrm{K\_Pi}}+\frac{\mathrm{GAP}\mathrm{NAD}}{\mathrm{K\_GAP}\mathrm{K\_NAD}}+\frac{\mathrm{GAP}\mathrm{NAD}\mathrm{Pi\_}}{\mathrm{K\_GAP}\mathrm{K\_NAD}\mathrm{K\_Pi}}+\frac{\mathrm{Thirteen\_BPG}}{\mathrm{K\_Thirteen\_BPG}}+\frac{\mathrm{NADH}}{\mathrm{K\_NADH}}+\frac{\mathrm{Thirteen\_BPG}\mathrm{NADH}}{\mathrm{K\_Thirteen\_BPG}\mathrm{K\_NADH}}$ $\frac{\mathrm{V\_max\_f}\times 1\mathrm{K\_Thirteen\_BPG}\mathrm{K\_NADH}}{\mathrm{K\_GAP}\mathrm{K\_NAD}\mathrm{K\_Pi}\mathrm{Keq\_GAPDH}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{Thirteen\_BPG}\mathrm{ADP}}{\mathrm{K\_Thirteen\_BPG}\mathrm{K\_ADP}}-\mathrm{V\_max\_r}\frac{\mathrm{three\_PG}\mathrm{ATP}}{\mathrm{K\_three\_PG}\mathrm{K\_ATP}}}{1+\frac{\mathrm{Thirteen\_BPG}}{\mathrm{K\_Thirteen\_BPG}}+\frac{\mathrm{ADP}}{\mathrm{K\_ADP}}+\frac{\mathrm{Thirteen\_BPG}\mathrm{ADP}}{\mathrm{K\_Thirteen\_BPG}\mathrm{K\_ADP}}+\frac{\mathrm{three\_PG}}{\mathrm{K\_three\_PG}}+\frac{\mathrm{ATP}}{\mathrm{K\_ATP}}+\frac{\mathrm{three\_PG}\mathrm{ATP}}{\mathrm{K\_three\_PG}\mathrm{K\_ATP}}}$ $\frac{\mathrm{V\_max\_r}\mathrm{K\_Thirteen\_BPG}\mathrm{K\_ADP}\mathrm{Keq\_PGK}}{\mathrm{K\_three\_PG}\mathrm{K\_ATP}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{three\_PG}}{\mathrm{K\_three\_PG}}-\mathrm{V\_max\_r}\frac{\mathrm{two\_PG}}{\mathrm{K\_two\_PG}}}{1+\frac{\mathrm{three\_PG}}{\mathrm{K\_three\_PG}}+\frac{\mathrm{two\_PG}}{\mathrm{K\_two\_PG}}}$ $\frac{\mathrm{V\_max\_f}\mathrm{K\_two\_PG}}{\mathrm{K\_three\_PG}\mathrm{Keq\_PGM}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{two\_PG}}{\mathrm{K\_two\_PG}}-\mathrm{V\_max\_r}\frac{\mathrm{PEP}}{\mathrm{K\_PEP}}}{1+\frac{\mathrm{two\_PG}}{\mathrm{K\_two\_PG}}+\frac{\mathrm{PEP}}{\mathrm{K\_PEP}}}$ $\frac{\mathrm{V\_max\_f}\mathrm{K\_PEP}}{\mathrm{K\_two\_PG}\mathrm{Keq\_ENOL}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{PEP}\mathrm{ADP}}{\mathrm{K\_PEP}\mathrm{K\_ADP}}-\mathrm{V\_max\_r}\frac{\mathrm{PYR}\mathrm{ATP}}{\mathrm{K\_PYR}\mathrm{K\_ATP}}}{1+\frac{\mathrm{PEP}}{\mathrm{K\_PEP}}+\frac{\mathrm{ADP}}{\mathrm{K\_ADP}}+\frac{\mathrm{PEP}\mathrm{ADP}}{\mathrm{K\_PEP}\mathrm{K\_ADP}}+\frac{\mathrm{PYR}}{\mathrm{K\_PYR}}+\frac{\mathrm{ATP}}{\mathrm{K\_ATP}}+\frac{\mathrm{PYR}\mathrm{ATP}}{\mathrm{K\_PYR}\mathrm{K\_ATP}}}$ $\frac{\mathrm{V\_max\_f}\mathrm{K\_ATP}\mathrm{K\_PYR}}{\mathrm{K\_PEP}\mathrm{K\_ADP}\mathrm{Keq\_PK}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{PYR}\mathrm{NADH}}{\mathrm{K\_PYR}\mathrm{K\_NADH}}-\mathrm{V\_max\_r}\frac{\mathrm{LAC}\mathrm{NAD}}{\mathrm{K\_LAC}\mathrm{K\_NAD}}}{1+\frac{\mathrm{PYR}}{\mathrm{K\_PYR}}+\frac{\mathrm{NADH}}{\mathrm{K\_NADH}}+\frac{\mathrm{PYR}\mathrm{NADH}}{\mathrm{K\_PYR}\mathrm{K\_NADH}}+\frac{\mathrm{LAC}}{\mathrm{K\_LAC}}+\frac{\mathrm{NAD}}{\mathrm{K\_NAD}}+\frac{\mathrm{LAC}\mathrm{NAD}}{\mathrm{K\_LAC}\mathrm{K\_NAD}}}$ $\frac{\mathrm{V\_max\_f}\mathrm{K\_LAC}\mathrm{K\_NAD}}{\mathrm{K\_PYR}\mathrm{K\_NADH}\mathrm{Keq\_LDH}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{ATP}\mathrm{Cr}}{\mathrm{Ki\_ATP}\mathrm{K\_Cr}}-\mathrm{V\_max\_r}\frac{\mathrm{ADP}\mathrm{PCr}}{\mathrm{Ki\_ADP}\mathrm{K\_PCr}}}{1+\frac{\mathrm{ADP}}{\mathrm{Ki\_ADP}}+\frac{\mathrm{PCr}}{\mathrm{Ki\_PCr}}+\frac{\mathrm{ADP}\mathrm{PCr}}{\mathrm{Ki\_ADP}\mathrm{K\_PCr}}+\frac{\mathrm{ATP}}{\mathrm{Ki\_ATP}}+\frac{\mathrm{ATP}\mathrm{Cr}}{\mathrm{Ki\_ATP}\mathrm{K\_Cr}}}$ $\frac{\mathrm{V\_max\_r}\mathrm{Ki\_ATP}\mathrm{K\_Cr}\mathrm{Keq\_CK}}{\mathrm{Ki\_ADP}\mathrm{K\_PCr}}$ $\frac{\mathrm{V\_max\_f}\frac{\mathrm{ATP}\mathrm{AMP}}{\mathrm{K\_ATP}\mathrm{K\_AMP}}-\mathrm{V\_max\_r}\frac{\mathrm{ADP}^2}{\mathrm{K\_ADP}^2}}{1+\frac{\mathrm{ATP}}{\mathrm{K\_ATP}}+\frac{\mathrm{AMP}}{\mathrm{K\_AMP}}+\frac{\mathrm{ATP}\mathrm{AMP}}{\mathrm{K\_ATP}\mathrm{K\_AMP}}+\frac{2\mathrm{ADP}}{\mathrm{K\_ADP}}+\frac{\mathrm{ADP}^2}{\mathrm{K\_ADP}^2}}$ $\frac{\mathrm{V\_max\_f}\mathrm{K\_ADP}^2}{\mathrm{K\_ATP}\mathrm{K\_AMP}\mathrm{Keq\_ADK}}$