//Created by libAntimony v2.4 model gonzalezheydrich_steingard_kohane_model_1994_version01__environment(time_) // Variable initializations: time_ = ; end model gonzalezheydrich_steingard_kohane_model_1994_version01__cortisol(cortisol, ACTH, time_) // Rate Rules: cortisol' = (k1 * ACTH + k2) - k3 * cortisol; // Variable initializations: cortisol = 0.0; k1 = 5E5; k2 = 0.01; k3 = 0.01; ACTH = ; time_ = ; end model gonzalezheydrich_steingard_kohane_model_1994_version01__ACTH(ACTH, CRH, cortisol, time_) // Rate Rules: ACTH' = (k4 * CRH + k5) - (k6 * ACTH + (k4 * CRH + k5) * ((Imax * cortisol) / (Kd + cortisol))); // Variable initializations: ACTH = 0.0; k4 = 10.0; k5 = 4E-3; k6 = 0.035; Kd = 0.004; Imax = 0.99; CRH = ; cortisol = ; time_ = ; end model gonzalezheydrich_steingard_kohane_model_1994_version01__CRH(CRH, time_) // Rate Rules: CRH' = (pulse + k7) - k8 * CRH; // Variable initializations: CRH = 50.0; k7 = 1E-6; k8 = 0.01; pulse = 50.0; time_ = ; end model *gonzalezheydrich_steingard_kohane_model_1994_version01____main() // Sub-modules, and any changes to those submodules: environment: gonzalezheydrich_steingard_kohane_model_1994_version01__environment(time_); cortisol: gonzalezheydrich_steingard_kohane_model_1994_version01__cortisol(cortisol0, ACTH0, time_); ACTH: gonzalezheydrich_steingard_kohane_model_1994_version01__ACTH(ACTH0, CRH0, cortisol0, time_); CRH: gonzalezheydrich_steingard_kohane_model_1994_version01__CRH(CRH0, time_); end