// Created by libAntimony v2.8.0
model *Das2010___Effect_of_a_gamma_secretase_inhibitor_on_Amyloid_beta_dynamics()

  // Compartments and Species:
  compartment CSF, Plasma;
  species $C in CSF, $P in Plasma;

  // Assignment Rules:
  g_t := piecewise(time/tauCSF*aCSF*exp(-bCSF*tauCSF), time < tauCSF, aCSF*exp(-bCSF*time));
  f_t := piecewise(time/tauplasma*aplasma*exp(-bplasma*tauplasma), time < tauplasma, aplasma*exp(-bplasma*time));

  // Rate Rules:
  C' = Sc/(1 + g_t/Ki) - k1*C + J;
  P' = k1*r*C - J*r - deltap*P*l;
  l' = epsilon*(1/(1 + alpha*f_t) - l);

  // Species initializations:
  C = 1;
  P = 1;

  // Compartment initializations:
  CSF = 1;
  Plasma = 1;

  // Variable initializations:
  Sc = 1.16;
  Ki = 0.0232;
  k1 = 1.13;
  J = 0;
  r = 0.43;
  deltap = 0.55;
  l = 1;
  epsilon = 0.0206;
  alpha = 0.522;
  tauCSF = 2.06;
  aCSF = 4.92;
  bCSF = 0.259;
  tauplasma = 1.66;
  aplasma = 187;
  bplasma = 0.089;

  // Other declarations:
  var g_t, l, f_t;
  const CSF, Plasma, Sc, Ki, k1, J, r, deltap, epsilon, alpha, tauCSF, aCSF;
  const bCSF, tauplasma, aplasma, bplasma;

  // Unit definitions:
  unit volume = 1e-3 litre;
  unit time_unit = 3600 second;
  unit substance = 1e-3 mole;

  // Display Names:
  time_unit is "time";
  g_t is "g(t)";
  f_t is "f(t)";
end