// Created by libAntimony v2.8.0 model *MODEL1309060000() // Compartments and Species: compartment compartment01; species Ras2_GDP in compartment01, Cdc25 in compartment01, Ras2_GDP_Cdc25 in compartment01; species Ras2_Cdc25 in compartment01, $GDP in compartment01, $GTP in compartment01; species Ras2_GTP_Cdc25 in compartment01, Ras2_GTP in compartment01, Ira2 in compartment01; species Ras2_GTP_Ira2 in compartment01, CYR1 in compartment01, Ras2_GTP_CYR1 in compartment01; species $ATP in compartment01, cAMP in compartment01, PKA in compartment01; species cAMP_PKA in compartment01, IIcAMP_PKA in compartment01, IIIcAMP_PKA in compartment01; species IVcAMP_PKA in compartment01, C in compartment01, R_2cAMP in compartment01; species R in compartment01, R_C in compartment01, Pde1 in compartment01; species Pde1f in compartment01, cAMP_Pde1f in compartment01, AMP in compartment01; species PPA2 in compartment01, Pde2 in compartment01, cAMP_Pde2 in compartment01; species Cdc25f in compartment01, Ira2P in compartment01, Ras2_GTP_Ira2P in compartment01; // Reactions: R0: Ras2_GDP + Cdc25 => Ras2_GDP_Cdc25; K0*Ras2_GDP*Cdc25; R1: Ras2_GDP_Cdc25 => Ras2_GDP + Cdc25; K1*Ras2_GDP_Cdc25; R2: Ras2_GDP_Cdc25 => Ras2_Cdc25 + $GDP; K2*Ras2_GDP_Cdc25; R3: Ras2_Cdc25 + $GDP => Ras2_GDP_Cdc25; K3*Ras2_Cdc25*GDP; R4: Ras2_Cdc25 + $GTP => Ras2_GTP_Cdc25; K4*Ras2_Cdc25*GTP; R5: Ras2_GTP_Cdc25 => Ras2_Cdc25 + $GTP; K5*Ras2_GTP_Cdc25; R6: Ras2_GTP_Cdc25 => Cdc25 + Ras2_GTP; K6*Ras2_GTP_Cdc25; R7: Cdc25 + Ras2_GTP => Ras2_GTP_Cdc25; K7*Cdc25*Ras2_GTP; R8: Ras2_GTP + Ira2 => Ras2_GTP_Ira2; K8*Ras2_GTP*Ira2; R9: Ras2_GTP_Ira2 => Ras2_GDP + Ira2; K9*Ras2_GTP_Ira2; R10: Ras2_GTP + CYR1 => Ras2_GTP_CYR1; K10*Ras2_GTP*CYR1; R11: Ras2_GTP_CYR1 + $ATP => Ras2_GTP_CYR1 + cAMP; K11*Ras2_GTP_CYR1*ATP; R12: Ira2 + Ras2_GTP_CYR1 => Ras2_GDP + Ira2 + CYR1; K12*Ira2*Ras2_GTP_CYR1; R13: cAMP + PKA => cAMP_PKA; K13*cAMP*PKA; R14: cAMP + cAMP_PKA => IIcAMP_PKA; K14*cAMP*cAMP_PKA; R15: cAMP + IIcAMP_PKA => IIIcAMP_PKA; K15*cAMP*IIcAMP_PKA; R16: cAMP + IIIcAMP_PKA => IVcAMP_PKA; K16*cAMP*IIIcAMP_PKA; R17: IVcAMP_PKA => cAMP + IIIcAMP_PKA; K17*IVcAMP_PKA; R18: IIIcAMP_PKA => cAMP + IIcAMP_PKA; K18*IIIcAMP_PKA; R19: IIcAMP_PKA => cAMP + cAMP_PKA; K19*IIcAMP_PKA; R20: cAMP_PKA => cAMP + PKA; K20*cAMP_PKA; R21: IVcAMP_PKA => 2C + 2R_2cAMP; K21*IVcAMP_PKA; R22: R_2cAMP => 2cAMP + R; K22*R_2cAMP; R23: C + R => R_C; K23*C*R; R24: 2R_C => PKA; K24*((R_C*(R_C - 1))/2); R25: C + Pde1 => C + Pde1f; K25*C*Pde1; R26: cAMP + Pde1f => cAMP_Pde1f; K26*cAMP*Pde1f; R27: cAMP_Pde1f => cAMP + Pde1f; K27*cAMP_Pde1f; R28: cAMP_Pde1f => Pde1f + AMP; K28*cAMP_Pde1f; R29: Pde1f + PPA2 => Pde1 + PPA2; K29*Pde1f*PPA2; R30: cAMP + Pde2 => cAMP_Pde2; K30*cAMP*Pde2; R31: cAMP_Pde2 => cAMP + Pde2; K31*cAMP_Pde2; R32: cAMP_Pde2 => AMP + Pde2; K32*cAMP_Pde2; R33: Cdc25 + C => C + Cdc25f; K33*Cdc25*C; R34: PPA2 + Cdc25f => Cdc25 + PPA2; K34*PPA2*Cdc25f; R35: Ira2 + C => C + Ira2P; K35*Ira2*C; R36: Ras2_GTP + Ira2P => Ras2_GTP_Ira2P; K36*Ras2_GTP*Ira2P; R37: Ras2_GTP_Ira2P => Ras2_GDP + Ira2P; K37*Ras2_GTP_Ira2P; R38: Ira2P => Ira2; K38*Ira2P; // Species initializations: Ras2_GDP = 20000/compartment01; Cdc25 = 300/compartment01; Ras2_GDP_Cdc25 = 0; Ras2_Cdc25 = 0; GDP = 1500000/compartment01; GTP = 5000000/compartment01; Ras2_GTP_Cdc25 = 0; Ras2_GTP = 0; Ira2 = 200/compartment01; Ras2_GTP_Ira2 = 0; CYR1 = 200/compartment01; Ras2_GTP_CYR1 = 0; ATP = 24000000/compartment01; cAMP = 0; PKA = 2500/compartment01; cAMP_PKA = 0; IIcAMP_PKA = 0; IIIcAMP_PKA = 0; IVcAMP_PKA = 0; C = 0; R_2cAMP = 0; R = 0; R_C = 0; Pde1 = 1400/compartment01; Pde1f = 0; cAMP_Pde1f = 0; AMP = 0; PPA2 = 4000/compartment01; Pde2 = 6500/compartment01; cAMP_Pde2 = 0; Cdc25f = 0; Ira2P = 0; Ras2_GTP_Ira2P = 0; // Compartment initializations: compartment01 = 1; // Variable initializations: K0 = 1; K0 has per_second; K1 = 1; K1 has per_second; K2 = 1.5; K2 has per_second; K3 = 1; K3 has per_second; K4 = 1; K4 has per_second; K5 = 1; K5 has per_second; K6 = 1; K6 has per_second; K7 = 1; K7 has per_second; K8 = 0.01; K8 has per_second; K9 = 0.25; K9 has per_second; K10 = 0.001; K10 has per_second; K11 = 2.1e-006; K11 has per_second; K12 = 0.001; K12 has per_second; K13 = 1e-005; K13 has per_second; K14 = 1e-005; K14 has per_second; K15 = 1e-005; K15 has per_second; K16 = 1e-005; K16 has per_second; K17 = 0.1; K17 has per_second; K18 = 0.1; K18 has per_second; K19 = 0.1; K19 has per_second; K20 = 0.1; K20 has per_second; K21 = 1; K21 has per_second; K22 = 1; K22 has per_second; K23 = 0.75; K23 has per_second; K24 = 1; K24 has per_second; K25 = 1e-006; K25 has per_second; K26 = 0.1; K26 has per_second; K27 = 0.1; K27 has per_second; K28 = 7.5; K28 has per_second; K29 = 0.0001; K29 has per_second; K30 = 0.0001; K30 has per_second; K31 = 1; K31 has per_second; K32 = 1.7; K32 has per_second; K33 = 1; K33 has per_second; K34 = 0.01; K34 has per_second; K35 = 0.001; K35 has per_second; K36 = 1.25; K36 has per_second; K37 = 2.5; K37 has per_second; K38 = 10; K38 has per_second; // Other declarations: const compartment01, K0, K1, K2, K3, K4, K5, K6, K7, K8, K9, K10, K11, K12; const K13, K14, K15, K16, K17, K18, K19, K20, K21, K22, K23, K24, K25, K26; const K27, K28, K29, K30, K31, K32, K33, K34, K35, K36, K37, K38; // Unit definitions: unit volume = dimensionless; unit substance = dimensionless; unit per_second = 1 / second; end