// Created by libAntimony v2.8.0
model *BIOMD0000000462()

  // Compartments and Species:
  compartment cell;
  substanceOnly species Abeta in cell, AbDim in cell, AbP in cell, $Source in cell;
  substanceOnly species $Sink in cell, Nep in cell;

  // Reactions:
  Abetaproduction: $Source => Abeta; kprod*Source;
  AbetaDegradation: Abeta + Nep => $Sink + Nep; kdeg*Abeta*Nep*0.001;
  AbetaDimerisation: 2Abeta => AbDim; kdimer*Abeta*(Abeta - 1)*0.5;
  AbetaDedimerisation: AbDim => 2Abeta; kdedimer*AbDim;
  AbetaPlaqueFormation: 2AbDim => 4AbP; kpf*AbDim*(AbDim - 1)*0.5;
  AbetaPlaqueGrowth: Abeta + AbP => 2AbP; (kpg*Abeta*AbP^2)/(kpghalf^2 + AbP^2);
  AbetaDisaggregation: AbP => Abeta; kdisagg*AbP;
  NepDegradation: Nep => $Sink; kdegNep*Nep;

  // Species initializations:
  Abeta = 0;
  AbDim = 0;
  AbP = 0;
  Source = 1/cell;
  Sink = 1/cell;
  Nep = 1000/cell;

  // Compartment initializations:
  cell = 1;

  // Variable initializations:
  kprod = 1.86e-005;
  kdeg = 2.1e-005;
  kdimer = 1.1783e-007;
  kdedimer = 8.4655e-006;
  kdisagg = 5.4357e-005;
  kpf = 2.785e-006;
  kpg = 0.00574;
  kpghalf = 4;
  kdegNep = 1.8e-010;

  // Other declarations:
  const cell, kprod, kdeg, kdimer, kdedimer, kdisagg, kpf, kpg, kpghalf, kdegNep;

  // Unit definitions:
  unit substance = item;

  // Display Names:
  Abeta is "AbetaMonomer";
  AbDim is "AbetaDimer";
  AbP is "AbetaPlaque";
  Nep is "Neprilysin";
end