// Created by libAntimony v2.8.0 model *Rattanakul2003_BoneFormationModel() // Compartments and Species: compartment Compartment_; species $x in Compartment_, $y in Compartment_, $z in Compartment_; // Rate Rules: x' = a1/(k1 + y) - b1*x; y' = epsilon*(((a2 + a3*x)*y*z)/(k2 + x^2) - b2*y); z' = epsilon*delta*(a4*x - (b3*z + (a5*x*z)/(k3 + x))); // Species initializations: x = 2; y = 1; z = 0.15; // Compartment initializations: Compartment_ = 1; Compartment_ has litre; // Variable initializations: a1 = 0.05; k1 = 0.1; b1 = 0.1; epsilon = 0.1; a2 = 0.009; a3 = 0.675; k2 = 0.5; b2 = 0.3; delta = 0.9; a4 = 0.01; b3 = 0.01; a5 = 0.005; k3 = 0.025; // Other declarations: const Compartment_, a1, k1, b1, epsilon, a2, a3, k2, b2, delta, a4, b3; const a5, k3; // Unit definitions: unit minute = 60 second; unit time_unit = 60 second; // Display Names: time_unit is "time"; x is "PTH"; y is "active osteoclasts"; z is "active osteoblasts"; end