// Created by libAntimony v2.8.0 model *Wolf2000_Glycolytic_Oscillations() // Compartments and Species: compartment compartment_; species s1 in compartment_, at_ in compartment_, s2 in compartment_, s3 in compartment_; species na in compartment_, s4 in compartment_, s5 in compartment_, s6 in compartment_; species s6o in compartment_; // Reactions: v1: s1 + 2at_ -> s2; (compartment_*k1*s1*at_)/(1 + (at_/ki)^n); v2: s2 -> 2s3; compartment_*k2*s2; v3: s3 + na -> s4 + at_; compartment_*((k31*k32*s3*na*(atot - at_) - k33*k34*s4*at_*(ntot - na))/(k33*(ntot - na) + k32*(atot - at_))); v4: s4 -> s5 + at_; compartment_*k4*s4*(atot - at_); v5: s5 -> s6; compartment_*k5*s5; v7: at_ -> ; compartment_*k7*at_; v8: s3 -> na; compartment_*k8*s3*(ntot - na); v9: s6o -> ; compartment_*k9*s6o; v10: s6 -> 0.1s6o; compartment_*k10*(s6 - s6o); v6: s6 -> na; compartment_*k6*s6*(ntot - na); v0: -> s1; compartment_*k0; // Species initializations: s1 = 1; at_ = 2; s2 = 5; s3 = 0.6; na = 0.6; s4 = 0.7; s5 = 8; s6 = 0.08; s6o = 0.02; // Compartment initializations: compartment_ = 1; // Variable initializations: k0 = 50; k0 has mM_min_1; k1 = 550; k1 has mM_1_min_1; k2 = 9.8; k2 has min_1; k31 = 323.8; k31 has mM_1_min_1; k33 = 57823.1; k33 has mM_1_min_1; k32 = 76411.1; k32 has mM_1_min_1; k34 = 23.7; k34 has mM_1_min_1; k4 = 80; k4 has mM_1_min_1; k5 = 9.7; k5 has min_1; k6 = 2000; k6 has mM_1_min_1; k7 = 28; k7 has min_1; k8 = 85.7; k8 has mM_1_min_1; k9 = 80; k9 has min_1; k10 = 375; k10 has min_1; atot = 4; atot has mM; ntot = 1; ntot has mM; n = 4; n has dimensionless; ki = 1; ki has mM; // Other declarations: const compartment_, k0, k1, k2, k31, k33, k32, k34, k4, k5, k6, k7, k8; const k9, k10, atot, ntot, n, ki; // Unit definitions: unit substance = 1e-3 mole; unit time_unit = 60 second; unit mM = 1e-3 mole / litre; unit mM_min_1 = 1e-3 mole / (litre * 60 second); unit min_1 = 1 / 60 second; unit mM_1_min_1 = litre / (1e-3 mole * 60 second); // Display Names: substance is "milli mole"; time_unit is "min"; s1 is "Glucose"; at_ is "ATP"; s2 is "F16P"; s3 is "Triose_Gly3Phos_DHAP"; na is "NAD"; s4 is "3PG"; s5 is "Pyruvate"; s6 is "Acetaldehyde"; s6o is "extracellular acetaldehyde"; end