// Created by libAntimony v2.8.0 model *Bray1995_chemotaxis_receptorlinkedcomplex() // Compartments and Species: compartment cell; species AA in cell, AAp in cell, W in cell, WAA in cell, WAAp in cell, WWAA in cell; species WWAAp in cell, TT in cell, TTW in cell, TTWW in cell, TTWAA in cell; species TTWAAp in cell, TTAA in cell, TTAAp in cell, TTWWAA in cell, TTWWAAp in cell; species Y in cell, Yp in cell, Z in cell, B in cell, Bp in cell, SetYp in cell; // Assignment Rules: Bias := 1 - Yp^Hill/(2.333*SetYp^Hill + Yp^Hill); // Reactions: complex_r1: TTW -> TT + W; cell*(complex_r1_k1*TTW - complex_r1_k2*TT*W); complex_r2: WAA -> W + AA; cell*(complex_r2_k1*WAA - complex_r2_k2*W*AA); complex_r3: TTWAA -> TT + WAA; cell*(complex_r3_k1*TTWAA - complex_r3_k2*TT*WAA); complex_r4: TTWWAA -> TTW + WAA; cell*(complex_r4_k1*TTWWAA - complex_r4_k2*TTW*WAA); complex_r5: TTWWAA -> TTWW + AA; cell*(complex_r5_k1*TTWWAA - complex_r5_k2*TTWW*AA); complex_r6: TTWWAA -> TT + WWAA; cell*(complex_r6_k1*TTWWAA - complex_r6_k2*TT*WWAA); complex_r7: TTAA -> TT + AA; cell*(complex_r7_k1*TTAA - complex_r7_k2*TT*AA); complex_r8: TTWAA -> TTW + AA; cell*(complex_r8_k1*TTWAA - complex_r8_k2*TTW*AA); complex_r9: TTWWAA -> TTWAA + W; cell*(complex_r9_k1*TTWWAA - complex_r9_k2*TTWAA*W); complex_r10: TTWW -> TTW + W; cell*(complex_r10_k1*TTWW - complex_r10_k2*TTW*W); complex_r11: WWAA -> W + WAA; cell*(complex_r11_k1*WWAA - complex_r11_k2*W*WAA); complex_r12: TTWAA -> TTAA + W; cell*(complex_r12_k1*TTWAA - complex_r12_k2*TTAA*W); phosphorylation_r1: TTWWAA => TTWWAAp; cell*phosphorylation_r1_k1*TTWWAA; phosphorylation_r2: AA => AAp; cell*phosphorylation_r2_k1*AA; phosphorylation_r3: WAA => WAAp; cell*phosphorylation_r3_k1*WAA; phosphorylation_r4: WWAA => WWAAp; cell*phosphorylation_r4_k1*WWAA; phosphorylation_r5: TTAA => TTAAp; cell*phosphorylation_r5_k1*TTAA; phosphorylation_r6: TTWAA => TTWAAp; cell*phosphorylation_r6_k1*TTWAA; phosphorylation_r7: Y => Yp; cell*phosphorylation_r7_k1*Y; phosphorylation_r8: Yp => Y; cell*phosphorylation_r8_k1*Yp; phosphorylation_r9: Yp + Z => Y + Z; cell*phosphorylation_r9_k1*Yp*Z; phosphorylation_r10: Bp => B; cell*phosphorylation_r10_k1*Bp; phosphotransfer_r1: B + AAp => Bp + AA; cell*phosphotransfer_r1_k1*B*AAp; phosphotransfer_r2: B + WAAp => Bp + WAA; cell*phosphotransfer_r2_k1*B*WAAp; phosphotransfer_r3: B + WWAAp => Bp + WWAA; cell*phosphotransfer_r3_k1*B*WWAAp; phosphotransfer_r4: B + TTAAp => Bp + TTAA; cell*phosphotransfer_r4_k1*B*TTAAp; phosphotransfer_r5: B + TTWAAp => Bp + TTWAA; cell*phosphotransfer_r5_k1*B*TTWAAp; phosphotransfer_r6: B + TTWWAAp => Bp + TTWWAA; cell*phosphotransfer_r6_k1*B*TTWWAAp; phosphotransfer_r7: Y + AAp => Yp + AA; cell*phosphotransfer_r7_k1*Y*AAp; phosphotransfer_r8: Y + WAAp => Yp + WAA; cell*phosphotransfer_r8_k1*Y*WAAp; phosphotransfer_r9: Y + WWAAp => Yp + WWAA; cell*phosphotransfer_r9_k1*Y*WWAAp; phosphotransfer_r10: Y + TTAAp => Yp + TTAA; cell*phosphotransfer_r10_k1*Y*TTAAp; phosphotransfer_r11: Y + TTWAAp => Yp + TTWAA; cell*phosphotransfer_r11_k1*Y*TTWAAp; phosphotransfer_r12: Y + TTWWAAp => Yp + TTWWAA; cell*phosphotransfer_r12_k1*Y*TTWWAAp; // Species initializations: AA = 2.5e-006; AAp = 0; W = 5e-006; WAA = 0; WAAp = 0; WWAA = 0; WWAAp = 0; TT = 2.5e-006; TTW = 0; TTWW = 0; TTWAA = 0; TTWAAp = 0; TTAA = 0; TTAAp = 0; TTWWAA = 0; TTWWAAp = 0; Y = 1e-005; Yp = 0; Z = 2e-005; B = 2e-006; Bp = 0; SetYp = 1.63e-006; // Compartment initializations: cell = 1.41; // Variable initializations: Hill = 4; Bias has dimensionless; complex_r1_k1 = 0.00365; complex_r1_k1 has persec; complex_r1_k2 = 1000000; complex_r1_k2 has perMpersec; complex_r2_k1 = 0.00894; complex_r2_k1 has persec; complex_r2_k2 = 1000000; complex_r2_k2 has perMpersec; complex_r3_k1 = 297; complex_r3_k1 has persec; complex_r3_k2 = 1000000; complex_r3_k2 has perMpersec; complex_r4_k1 = 0.64; complex_r4_k1 has persec; complex_r4_k2 = 1000000; complex_r4_k2 has perMpersec; complex_r5_k1 = 0.112; complex_r5_k1 has persec; complex_r5_k2 = 1000000; complex_r5_k2 has perMpersec; complex_r6_k1 = 0.0229; complex_r6_k1 has persec; complex_r6_k2 = 1000000; complex_r6_k2 has perMpersec; complex_r7_k1 = 39.3; complex_r7_k1 has persec; complex_r7_k2 = 1000000; complex_r7_k2 has perMpersec; complex_r8_k1 = 727; complex_r8_k1 has persec; complex_r8_k2 = 1000000; complex_r8_k2 has perMpersec; complex_r9_k1 = 7.87e-006; complex_r9_k1 has persec; complex_r9_k2 = 1000000; complex_r9_k2 has perMpersec; complex_r10_k1 = 0.0511; complex_r10_k1 has persec; complex_r10_k2 = 1000000; complex_r10_k2 has perMpersec; complex_r11_k1 = 0.102; complex_r11_k1 has persec; complex_r11_k2 = 1000000; complex_r11_k2 has perMpersec; complex_r12_k1 = 0.0676; complex_r12_k1 has persec; complex_r12_k2 = 1000000; complex_r12_k2 has perMpersec; phosphorylation_r1_k1 = 15.5; phosphorylation_r1_k1 has persec; phosphorylation_r2_k1 = 0.0227; phosphorylation_r2_k1 has persec; phosphorylation_r3_k1 = 0.0227; phosphorylation_r3_k1 has persec; phosphorylation_r4_k1 = 0.0227; phosphorylation_r4_k1 has persec; phosphorylation_r5_k1 = 0.0227; phosphorylation_r5_k1 has persec; phosphorylation_r6_k1 = 0.0227; phosphorylation_r6_k1 has persec; phosphorylation_r7_k1 = 0.00124; phosphorylation_r7_k1 has persec; phosphorylation_r8_k1 = 0.037; phosphorylation_r8_k1 has persec; phosphorylation_r9_k1 = 500000; phosphorylation_r9_k1 has perMpersec; phosphorylation_r10_k1 = 0.35; phosphorylation_r10_k1 has persec; phosphotransfer_r1_k1 = 6000000; phosphotransfer_r1_k1 has perMpersec; phosphotransfer_r2_k1 = 6000000; phosphotransfer_r2_k1 has perMpersec; phosphotransfer_r3_k1 = 6000000; phosphotransfer_r3_k1 has perMpersec; phosphotransfer_r4_k1 = 6000000; phosphotransfer_r4_k1 has perMpersec; phosphotransfer_r5_k1 = 6000000; phosphotransfer_r5_k1 has perMpersec; phosphotransfer_r6_k1 = 6000000; phosphotransfer_r6_k1 has perMpersec; phosphotransfer_r7_k1 = 30000000; phosphotransfer_r7_k1 has perMpersec; phosphotransfer_r8_k1 = 30000000; phosphotransfer_r8_k1 has perMpersec; phosphotransfer_r9_k1 = 30000000; phosphotransfer_r9_k1 has perMpersec; phosphotransfer_r10_k1 = 30000000; phosphotransfer_r10_k1 has perMpersec; phosphotransfer_r11_k1 = 30000000; phosphotransfer_r11_k1 has perMpersec; phosphotransfer_r12_k1 = 30000000; phosphotransfer_r12_k1 has perMpersec; // Other declarations: var Bias; const cell, Hill; // Unit definitions: unit perMpersec = litre / (mole * second); unit persec = 1 / second; unit volume = 1e-15 litre; unit M = mole / litre; unit Mpersec = mole / (litre * second); // Display Names: volume is "femtolitre"; SetYp is "setYp"; end