// Created by libAntimony v2.8.0 model *Zatorsky2006_p53_Model6() // Compartments and Species: compartment compartment_; species x in compartment_, y in compartment_; // Rate Rules: S' = beta_S - alpha_S*y*S; // Reactions: R1: => x; (compartment_*beta_x*S^n)/(S^n + 1)*psi; R3: x => ; compartment_*alpha_xy*y*x; R4: => y; compartment_*beta_y*psi*delay(x, tau); R5: y => ; compartment_*alpha_y*y; // Species initializations: x = 0; y = 0.9; // Compartment initializations: compartment_ = 1; // Variable initializations: beta_x = 0.9; psi = 1; alpha_xy = 1.4; beta_y = 1; alpha_y = 0.7; tau = 0.9; S = 0; beta_S = 0.9; alpha_S = 2.7; n = 4; // Other declarations: var S; const compartment_, beta_x, psi, alpha_xy, beta_y, alpha_y, tau, beta_S; const alpha_S, n; // Unit definitions: unit substance = item; unit time_unit = 3600 second; // Display Names: substance is "dimensionless"; time_unit is "hours"; compartment_ is "cell"; x is "p53"; y is "Mdm2"; R1 is "p53 production"; R3 is "Mdm2 dependent p53 degradation"; R4 is "p53 dependent Mdm2 production"; R5 is "Mdm2 degradation"; end